Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU002194 |
| Korean Unigene Clone | IRAT-23-G10 | |
| Original Clone | IRAK-32-I09 | |
| Vector | pBluescriptR | |
| Gene | ACVR1C | |
| Gene Description | activin A receptor type 1C | |
| Clone sequence size | 3267 (bp) | |
| Fullness | F | |
| Mutation | 332,911,1085,1211 | |
| Amino acid - mutation | TTC(F)-> TTT(F),TCT(S)-> TAT(Y),GTG(V)-> ATG(M),GTG(V)-> GTA(V) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 3267 |
| Sequence | GGTCACCGCCCGGCTGCGGGGCCAGTGGCAGGAGCGCCACGCACC GCCAGCCGCAGGGGGCGTGGGATGGGGGCGGCCGGGGAGGGGGGC GCCCACACTGACTAGAGCCAACCGCGCACTTCAAAAGGGTGTCGG TGCCGCGCTCCCCTCCCGCGGCCCGGGAACTTCAAAGCGGGCCGT GCTGCCCCGGCTGCCTCGCTCTGCTCTGGGGCCTCGCAGCCCCGG CGCGGCCGCCTGGTGGCGATGACCCGGGCGCTCTGCTCAGCGCTC CGCCAGGCTCTCCTGCTGCTCGCAGCGGCCGCCGAGCTCTCGCCA GGACTGAAGTGTGTATGTCTTTTGTGTGATTCTTCAAACTTTACC TGCCAAACAGAAGGAGCATGTTGGGCATCAGTCATGCTAACCAAT GGAAAAGAGCAGGTGATCAAATCCTGTGTCTCCCTTCCAGAACTG AATGCTCAAGTCTTCTGTCATAGTTCCAACAATGTTACCAAAACC GAATGCTGCTTCACAGATTTTTGCAACAACATAACACTGCACCTT CCAACAGCATCACCAAATGCCCCAAAACTTGGACCCATGGAGCTG GCCATCATTATTACTGTGCCTGTTTGCCTCCTGTCCATAGCTGCG ATGCTGACAGTATGGGCATGCCAGGGTCGACAGTGCTCCTACAGG AAGAAAAAGAGACCAAATGTGGAGGAACCACTCTCTGAGTGCAAT CTGGTAAATGCTGGAAAAACTCTGAAAGATCTGATTTATGATGTG ACCGCCTCTGGATCTGGCTCTGGTCTACCTCTGTTGGTTCAAAGG ACAATTGCAAGGACGATTGTGCTTCAGGAAATAGTAGGAAAAGGT AGATTTGGTGAGGTGTGGCATGGAAGATGGTGTGGGGAAGATGTG GCTGTGAAAATATTCTCCTCCAGAGATGAAAGATATTGGTTTCGT GAGGCAGAAATTTACCAGACGGTCATGCTGCGACATGAAAACATC CTTGGTTTCATTGCTGCTGACAACAAAGATAATGGAACTTGGACT CAACTTTGGCTGGTATCTGAATATCATGAACAGGGCTCCTTATAT GACTATTTGAATAGAAATATAGTGACCATGGCTGGAATGATCAAG CTGGCGCTCTCAATTGCTAGTGGTCTGGCACACCTTCATATGGAG ATTGTTGGTACACAAGGTAAACCTGCTATTGCTCATCGAGACATA AAATCAAAGAATATCTTAGTAAAAAAGTGTGAAACTTGTGCCATA GCGGACTTAGGGTTGGCTGTGAAGCATGATTCAATACTGAACACT ATCGACATACCTCAGAATCCTAAAGTGGGAACCAAGAGGTATATG GCTCCTGAAATGCTTGATGATACAATGAATGTGAATATCTTTGAG TCCTTCAAACGAGCTGACATCTATTCTGTTGGTCTGGTTTACTGG GAAATAGCCCGGAGGTGTTCAGTCGGAGGAATTGTTGAGGAGTAC CAATTGCCTTATTATGACATGGTGCCTTCAGATCCCTCGATAGAG GAAATGAGAAAGGTTGTTTGTGACCAGAAGTTTCGACCAAGTATC CCAAACCAGTGGCAAAGTTGTGAAGCACTCCGAGTCATGGGGAGA ATAATGCGTGAGTGTTGGTATGCCAACGGAGCGGCCCGCCTAACT GCTCTTCGTATTAAGAAGACTATATCTCAACTTTGTGTCAAAGAA GACTGCAAAGCCTAATGATGATAATTATGTTAAAAAGAAATCTCT CATAGCTTTCTTTTCCATTTTCCCCTTTATGTGAATGTTTTTGCC ATTTTTTTTTTGTTCTACCTCAAAGATAAGACAGTACAGTATTTA AGTGCCCATAAGGCAGCATGAAAAGATAACTCTAAAGTTAAGCAT GGGCAGGAGTTGACTTCATCCAATCTCTATGTTATGTTTAATTTT ATTTTGAAAGCAACACCTCAACTCATCTTTTTATTTAATAAGGAA GAAATATATTACAAAAGTATAAAATAAGCTCTATAAAAATGTTAT AGTCATTAAGTTTTTATTTTACTTGAACCAAGAGCACATGAATGA ACAGGAAAAGATGTAAAAACATTTTTTTCTGAGATGAAAACATAT TAATTAAACATGCAAATTAGAGCATGCTATCTTTAGGTGATGCAA TCTATGTTTCCCCCTTTTTAAGTTAGCAGGACTTTTTAAAAATAA ATATTGCTCTAAACTTTAATATATCGAACGTGAGAGTGGAGCTGC TTAGTGGAAGATGTAAGTGAGGTGGGTGTCCCATGTGCTTGGTCT CCCCTTCTGCTGTTCTCCTGTTCTTCATAATCCACTACTGCAGCA GTCCCTGAACCACTAAACTTGTTCCTTTCATTTACAAAAGAGATA CCTGACATCCTGAGACACTGAGAAATGTCCTGAAGTCACACAGCT AATGGCAGAACTGGCACTAGGTCCAAATCTTGTGATAATGAACAC CGTAAGGTTAGCTAGCTTCCTACTTTCCCTTGAATAGTGCTTTTC TCCCTATGTAATATCTTTTATTATGATATTTGTGGTTTAGAAGGC ATATTGAGTTATTTTGCAGAATCATAATGGACCCGCACAAAATCT CAGAACCATATCTGTTGACATTTTTTCTCATAGAAATATCATGGT TACCCCATTTGTTAATGAGCATTAATGTTTTCTGAACACTTCCAA AGATTAATCAAACATAAATATTCATTGTCTGAAAATGTCTTTAAG ATACAATTCAGAGGTCCCTATTTCCTTTGTACATACACACTTAGA AAGAAAAGACAGAAAAGGAAGAGGAAGGAAGGAAATATTTTGAGA ATATATTGAGAAGAATTAAGAAAACTCTTCAATGAAGTGTTAACA ACCAAACCCTACAGACGGTATCAGAAACAGCAAATAGATATTCCT CTACCCTTTCACAGTGAGTGAGTGAGTACAGAAGAATGCTCATGA TAGTTTTGCCTTCATTCTACTTTCTGTGGACACAGAGTAATGAAT ATTTAATGGGACATTAAATATGCCCTTCAAATCTATAATTTTACT TTGGTAAACGAGATTTAACATGATGTCTTTTATGCTCCTAAAACA TCTTTTTTCAAACTCCATTCCTTAGAACATTCTTCTACTGAGATG ATCCAAGACCAAAAGTGTTCTTTGGTACTTGCTTATAAAGTGATA GTACATGTTAGCATATAATGTATTTTGAAGAGTGAAGTAAATGCT ATTGATAACAGAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 2 | |||||||||||
| Location | 2q24.1 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_145259 | |||||||||||
| KEGG Genes | 130399 | ||||||||||||
| GeneCard | ACVR1C |
| sequence | sequence of CDS | ATGACCCGGGCGCTCTGCTCAGCGCTCCGCCAGGCTCTCCTGCTGCTCGCAGCGGCCGCCGAGCTCTCGCCAGGACTGAAGTGTGTATGTCTTTTGTGTGATTCTTCAAACTTCACCTGCCAAACAGAAGGAGCATGTTGGGCATCAGTCATGCTAACCAATGGAAAAGAGCAGGTGATCAAATCCTGTGTCTCCCTTCCAGAACTGAATGCTCAAGTCTTCTGTCATAGTTCCAACAATGTTACCAAAACCGAATGCTGCTTCACAGATTTTTGCAACAACATAACACTGCACCTTCCAACAGCATCACCAAATGCCCCAAAACTTGGACCCATGGAGCTGGCCATCATTATTACTGTGCCTGTTTGCCTCCTGTCCATAGCTGCGATGCTGACAGTATGGGCATGCCAGGGTCGACAGTGCTCCTACAGGAAGAAAAAGAGACCAAATGTGGAGGAACCACTCTCTGAGTGCAATCTGGTAAATGCTGGAAAAACTCTGAAAGATCTGATTTATGATGTGACCGCCTCTGGATCTGGCTCTGGTCTACCTCTGTTGGTTCAAAGGACAATTGCAAGGACGATTGTGCTTCAGGAAATAGTAGGAAAAGGTAGATTTGGTGAGGTGTGGCATGGAAGATGGTGTGGGGAAGATGTGGCTGTGAAAATATTCTCCTCCAGAGATGAAAGATCTTGGTTTCGTGAGGCAGAAATTTACCAGACGGTCATGCTGCGACATGAAAACATCCTTGGTTTCATTGCTGCTGACAACAAAGATAATGGAACTTGGACTCAACTTTGGCTGGTATCTGAATATCATGAACAGGGCTCCTTATATGACTATTTGAATAGAAATATAGTGACCGTGGCTGGAATGATCAAGCTGGCGCTCTCAATTGCTAGTGGTCTGGCACACCTTCATATGGAGATTGTTGGTACACAAGGTAAACCTGCTATTGCTCATCGAGACATAAAATCAAAGAATATCTTAGTGAAAAAGTGTGAAACTTGTGCCATAGCGGACTTAGGGTTGGCTGTGAAGCATGATTCAATACTGAACACTATCGACATACCTCAGAATCCTAAAGTGGGAACCAAGAGGTATATGGCTCCTGAAATGCTTGATGATACAATGAATGTGAATATCTTTGAGTCCTTCAAACGAGCTGACATCTATTCTGTTGGTCTGGTTTACTGGGAAATAGCCCGGAGGTGTTCAGTCGGAGGAATTGTTGAGGAGTACCAATTGCCTTATTATGACATGGTGCCTTCAGATCCCTCGATAGAGGAAATGAGAAAGGTTGTTTGTGACCAGAAGTTTCGACCAAGTATCCCAAACCAGTGGCAAAGTTGTGAAGCACTCCGAGTCATGGGGAGAATAATGCGTGAGTGTTGGTATGCCAACGGAGCGGCCCGCCTAACTGCTCTTCGTATTAAGAAGACTATATCTCAACTTTGTGTCAAAGAAGACTGCAAAGCCTAA |
| sequence of protein | MTRALCSALRQALLLLAAAAELSPGLKCVCLLCDSSNFTCQTEGACWASVMLTNGKEQVIKSCVSLPELNAQVFCHSSNNVTKTECCFTDFCNNITLHLPTASPNAPKLGPMELAIIITVPVCLLSIAAMLTVWACQGRQCSYRKKKRPNVEEPLSECNLVNAGKTLKDLIYDVTASGSGSGLPLLVQRTIARTIVLQEIVGKGRFGEVWHGRWCGEDVAVKIFSSRDERSWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSEYHEQGSLYDYLNRNIVTVAGMIKLALSIASGLAHLHMEIVGTQGKPAIAHRDIKSKNILVKKCETCAIADLGLAVKHDSILNTIDIPQNPKVGTKRYMAPEMLDDTMNVNIFESFKRADIYSVGLVYWEIARRCSVGGIVEEYQLPYYDMVPSDPSIEEMRKVVCDQKFRPSIPNQWQSCEALRVMGRIMRECWYANGAARLTALRIKKTISQLCVKEDCKA | |
| Database link | RefSeq | NM_145259 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008] |
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