Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU004003 |
| Korean Unigene Clone | IRAT-43-F07 | |
| Original Clone | IRAK-49-I09 | |
| Vector | pCMV-SPORT6 | |
| Gene | IL2RB | |
| Gene Description | interleukin 2 receptor subunit beta | |
| Clone sequence size | 4035 (bp) | |
| Fullness | F | |
| Mutation | 873 | |
| Amino acid - mutation | GGC(G)-> GGT(G) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 4035 |
| Sequence | GGGCCCTGGAGAGATGGCCACGGTCCCAGCACCGGGGAGGACTGG AGAGCGCGCGCTGCCACCGCCCCATGTCTCAGCCAGGGCTTCCTT CCTCGGCTCCACCCTGTGGATGTAATGGCGGCCCCTGCTCTGTCC TGGCGTCTGCCCCTCCTCATCCTCCTCCTGCCCCTGGCTACCTCT TGGGCATCTGCAGCGGTGAATGGCACTTCCCAGTTCACATGCTTC TACAACTCGAGAGCCAACATCTCCTGTGTCTGGAGCCAAGATGGG GCTCTGCAGGACACTTCCTGCCAAGTCCATGCCTGGCCGGACAGA CGGCGGTGGAACCAAACCTGTGAGCTGCTCCCCGTGAGTCAAGCA TCCTGGGCCTGCAACCTGATCCTCGGAGCCCCAGATTCTCAGAAA CTGACCACAGTTGACATCGTCACCCTGAGGGTGCTGTGCCGTGAG GGGGTGCGATGGAGGGTGATGGCCATCCAGGACTTCAAGCCCTTT GAGAACCTTCGCCTGATGGCCCCCATCTCCCTCCAAGTTGTCCAC GTGGAGACCCACAGATGCAACATAAGCTGGGAAATCTCCCAAGCC TCCCACTACTTTGAAAGACACCTGGAGTTCGAGGCCCGGACGCTG TCCCCAGGCCACACCTGGGAGGAGGCCCCCCTGCTGACTCTCAAG CAGAAGCAGGAATGGATCTGCCTGGAGACGCTCACCCCAGACACC CAGTATGAGTTTCAGGTGCGGGTCAAGCCTCTGCAAGGCGAGTTC ACGACCTGGAGCCCCTGGAGCCAGCCCCTGGCCTTCAGGACAAAG CCTGCAGCCCTTGGGAAGGACACCATTCCGTGGCTCGGCCACCTC CTCGTGGGTCTCAGCGGGGCTTTTGGCTTCATCATCTTAGTGTAC TTGCTGATCAACTGCAGGAACACCGGGCCATGGCTGAAGAAGGTC CTGAAGTGTAACACCCCAGACCCCTCGAAGTTCTTTTCCCAGCTG AGCTCAGAGCATGGAGGAGACGTCCAGAAGTGGCTCTCTTCGCCC TTCCCCTCATCGTCCTTCAGCCCTGGCGGCCTGGCACCTGAGATC TCGCCACTAGAAGTGCTGGAGAGGGACAAGGTGACGCAGCTGCTC CTGCAGCAGGACAAGGTGCCTGAGCCCGCATCCTTAAGCAGCAAC CACTCGCTGACCAGCTGCTTCACCAACCAGGGTTACTTCTTCTTC CACCTCCCGGATGCCTTGGAGATAGAGGCCTGCCAGGTGTACTTT ACTTACGACCCCTACTCAGAGGAAGACCCTGATGAGGGTGTGGCC GGGGCACCCACAGGGTCTTCCCCCCAACCCCTGCAGCCTCTGTCA GGGGAGGACGACGCCTACTGCACCTTCCCCTCCAGGGATGACCTG CTGCTCTTCTCCCCCAGTCTCCTCGGTGGCCCCAGCCCCCCAAGC ACTGCCCCTGGGGGCAGTGGGGCCGGTGAAGAGAGGATGCCCCCT TCTTTGCAAGAAAGAGTCCCCAGAGACTGGGACCCCCAGCCCCTG GGGCCTCCCACCCCAGGAGTCCCAGACCTGGTGGATTTTCAGCCA CCCCCTGAGCTGGTGCTGCGAGAGGCTGGGGAGGAGGTCCCTGAC GCTGGCCCCAGGGAGGGAGTCAGTTTCCCCTGGTCCAGGCCTCCT GGGCAGGGGGAGTTCAGGGCCCTTAATGCTCGCCTGCCCCTGAAC ACTGATGCCTACTTGTCCCTCCAAGAACTCCAGGGTCAGGACCCA ACTCACTTGGTGTAGACAGATGGCCAGGGTGGGAGGCAGGCAGCT GCCTGCTCTGCGCCGAGCCTCAGAAGGACCCTGTTGAGGGTCCTC AGTCCACTGCTGAGGACACTCAGTGTCCAGTTGCAGCTGGACTTC TCCACCCGGATGGCCCCCACCCAGTCCTGCACACTTGGTCCATCC ATTTCCAAACCTCCACTGCTGCTCCCGGGTCCTGCTGCCCGAGCC AGGAACTGTGTGTGTTGCAGGGGGGCAGTAACTCCCCAACTCCCT CGTTAATCACAGGATCCCACGAATTTAGGCTCAGAAGCATCGCTC CTCTCCAGCCCTGCAGCTATTCACCAATATCAGTCCTCGCGGCTC TCCAGGGCTCCCTGCCCTGACCTCTTCCCTGGGTTTTCTGCCCCA GCCTCCTCCTTCCCTCCCCTCCCCGTCCACAGGGCAGCCTGAGCG TGCTTTCCAAAACCCAAATATGGCCACGCTCCCCCTCGGTTCAAA ACCTTGCACAGGTCCCACTGCCCTCAGCCCCACTTCTCAGCCTGG TACTTGTACCTCCGGTGTCGTGTGGGGACATCCCCTTCTGCAATC CTCCCTACCGTCCTCCTGAGCCACTCAGAGCTCCCTCACACCCCC TCTGTTGCACATGCTATTCCCTGGGGCTGCTGTGCGCTCCCCCTC ATCTAGGTGACAAACTTCCCTGACTCTTCAAGTGCCGGTTTTGCT TCTCCTGGAGGGAAGCACTGCCTCCCTTAATCTGCCAGAAACTTC TAGCGTCAGTGCTGGAGGGAGAAGCTGTCAGGGACCCAGGGCGCC TGGAGAAAGAGGCCCTGTTACTATTCCTTTGGGATCTCTGAGGCC TCAGAGTGCTTGGCTGCTGTATCTTTAATGCTGGGGCCCAAGTAA GGGCACAGATCCCCCCACAAAGTGGATGCCTGCTGCATCTTCCCA CAGTGGCTTCACAGACCCACAAGAGAAGCTGATGGGGAGTAAACC CTGGAGTCCGAGGCCCAGGCAGCAGCCCCGCCTAGTGGTGGGCCC TGATGCTGCCAGGCCTGGGACCTCCCACTGCCCCCTCCACTGGAG GGGTCTCCTCTGCAGCTCAGGGACTGGCACACTGGCCTCCAGAAG GGCAGCTCCACAGGGCAGGGCCTCATTATTTTTCACTGCCCCAGA CACAGTGCCCAACACCCCGTCGTATACCCTGGATGAACGAATTAA TTACCTGGCACCACCTCGTCTGGGCTCCCTGCGCCTGACATTCAC ACAGAGAGGCAGAGTCCCGTGCCCATTAGGTCTGGCATGCCCCCT CCTGCAAGGGGCTCAACCCCCTACCCCGACCCCTCCACGTATCTT TCCTAGGCAGATCACGTTGCAATGGCTCAAACAACATTCCACCCC AGCAGGACAGTGACCCCAGTCCCAGCTAACTCTGACCTGGGAGCC CTCAGGCACCTGCACTTACAGGCCTTGCTCACAGCTGATTGGGCA CCTGACCACACGCCCCCACGGGCTCTGACCAGCAGCCTATGAGGG GGTTTGGCACCAAGCTCTGTCCAATCAGGTAGGCTGGGCCTGAAC TAGCCAATCAGATCAACTCTGTCTTGGGCGTTTGAACTCAGGGAG GGAGGCCCTTGGGAGCAGGTGCTTGTGGACAAGGCTCCACAAGCG TTGAGCCTTGGAAAGGTAGACAAGCGTTGAGCCACTAAGCAGAGG ACCTTGGGTTCCCAATACAAAAATACCTACTGCTGAGAGGGCTGC TGACCATTTGGTCAGGATTCCTGTTGCCTTTATATCCAAAATAAA CTCCCCTTTCTTGAGGTTGTCTGAGTCTTGGGTCTATGCCTTGAA AAAAGCTGAATTATTGGACAGTCTCACCTCCTGCCATAGGGTCCT GAATGTTTCAGACCACAAGGGGCTCCACACCTTTGCTGTGTGTTC TGGGGCAACCTACTAATCCTCTCTGCAAGTCGGTCTCCTTATCCC CCCAAATGGAAATTGTATTTGCCTTCTCCACTTTGGGAGGCTCCC ACTTCTTGGGAGGGTTACATTTTTTAAGTCTTAATCATTTGTGAC ATATGTATCTATACATCCGTATCTTTTAATGATCCGTGTGTACCA TCTTTGTGATTATTTTCTTAATATTTTTTCTTTAAGTCAGTTCAT TTTCGTTGAAATACATTTATTTAAAGAAAAATCTTTGTTACTCTG TAAATGAAAAAACCCATTTTCGCTATAAATAAAAGGTAACTGTAC AAAATAAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 22 | |||||||||||
| Location | 22q13.1 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_000878 | |||||||||||
| KEGG Genes | 3560 | ||||||||||||
| GeneCard | IL2RB |
| sequence | sequence of CDS | ATGGCGGCCCCTGCTCTGTCCTGGCGTCTGCCCCTCCTCATCCTCCTCCTGCCCCTGGCTACCTCTTGGGCATCTGCAGCGGTGAATGGCACTTCCCAGTTCACATGCTTCTACAACTCGAGAGCCAACATCTCCTGTGTCTGGAGCCAAGATGGGGCTCTGCAGGACACTTCCTGCCAAGTCCATGCCTGGCCGGACAGACGGCGGTGGAACCAAACCTGTGAGCTGCTCCCCGTGAGTCAAGCATCCTGGGCCTGCAACCTGATCCTCGGAGCCCCAGATTCTCAGAAACTGACCACAGTTGACATCGTCACCCTGAGGGTGCTGTGCCGTGAGGGGGTGCGATGGAGGGTGATGGCCATCCAGGACTTCAAGCCCTTTGAGAACCTTCGCCTGATGGCCCCCATCTCCCTCCAAGTTGTCCACGTGGAGACCCACAGATGCAACATAAGCTGGGAAATCTCCCAAGCCTCCCACTACTTTGAAAGACACCTGGAGTTCGAGGCCCGGACGCTGTCCCCAGGCCACACCTGGGAGGAGGCCCCCCTGCTGACTCTCAAGCAGAAGCAGGAATGGATCTGCCTGGAGACGCTCACCCCAGACACCCAGTATGAGTTTCAGGTGCGGGTCAAGCCTCTGCAAGGCGAGTTCACGACCTGGAGCCCCTGGAGCCAGCCCCTGGCCTTCAGGACAAAGCCTGCAGCCCTTGGGAAGGACACCATTCCGTGGCTCGGCCACCTCCTCGTGGGCCTCAGCGGGGCTTTTGGCTTCATCATCTTAGTGTACTTGCTGATCAACTGCAGGAACACCGGGCCATGGCTGAAGAAGGTCCTGAAGTGTAACACCCCAGACCCCTCGAAGTTCTTTTCCCAGCTGAGCTCAGAGCATGGAGGAGACGTCCAGAAGTGGCTCTCTTCGCCCTTCCCCTCATCGTCCTTCAGCCCTGGCGGCCTGGCACCTGAGATCTCGCCACTAGAAGTGCTGGAGAGGGACAAGGTGACGCAGCTGCTCCTGCAGCAGGACAAGGTGCCTGAGCCCGCATCCTTAAGCAGCAACCACTCGCTGACCAGCTGCTTCACCAACCAGGGTTACTTCTTCTTCCACCTCCCGGATGCCTTGGAGATAGAGGCCTGCCAGGTGTACTTTACTTACGACCCCTACTCAGAGGAAGACCCTGATGAGGGTGTGGCCGGGGCACCCACAGGGTCTTCCCCCCAACCCCTGCAGCCTCTGTCAGGGGAGGACGACGCCTACTGCACCTTCCCCTCCAGGGATGACCTGCTGCTCTTCTCCCCCAGTCTCCTCGGTGGCCCCAGCCCCCCAAGCACTGCCCCTGGGGGCAGTGGGGCCGGTGAAGAGAGGATGCCCCCTTCTTTGCAAGAAAGAGTCCCCAGAGACTGGGACCCCCAGCCCCTGGGGCCTCCCACCCCAGGAGTCCCAGACCTGGTGGATTTTCAGCCACCCCCTGAGCTGGTGCTGCGAGAGGCTGGGGAGGAGGTCCCTGACGCTGGCCCCAGGGAGGGAGTCAGTTTCCCCTGGTCCAGGCCTCCTGGGCAGGGGGAGTTCAGGGCCCTTAATGCTCGCCTGCCCCTGAACACTGATGCCTACTTGTCCCTCCAAGAACTCCAGGGTCAGGACCCAACTCACTTGGTGTAG |
| sequence of protein | MAAPALSWRLPLLILLLPLATSWASAAVNGTSQFTCFYNSRANISCVWSQDGALQDTSCQVHAWPDRRRWNQTCELLPVSQASWACNLILGAPDSQKLTTVDIVTLRVLCREGVRWRVMAIQDFKPFENLRLMAPISLQVVHVETHRCNISWEISQASHYFERHLEFEARTLSPGHTWEEAPLLTLKQKQEWICLETLTPDTQYEFQVRVKPLQGEFTTWSPWSQPLAFRTKPAALGKDTIPWLGHLLVGLSGAFGFIILVYLLINCRNTGPWLKKVLKCNTPDPSKFFSQLSSEHGGDVQKWLSSPFPSSSFSPGGLAPEISPLEVLERDKVTQLLLQQDKVPEPASLSSNHSLTSCFTNQGYFFFHLPDALEIEACQVYFTYDPYSEEDPDEGVAGAPTGSSPQPLQPLSGEDDAYCTFPSRDDLLLFSPSLLGGPSPPSTAPGGSGAGEERMPPSLQERVPRDWDPQPLGPPTPGVPDLVDFQPPPELVLREAGEEVPDAGPREGVSFPWSRPPGQGEFRALNARLPLNTDAYLSLQELQGQDPTHLV | |
| Database link | RefSeq | NM_000878 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq, Jul 2008] |
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