Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | KU000262 |
| Korean Unigene Clone | UG-0014-E03 | |
| Original Clone | S2SNU668s1-25-C01 | |
| Vector | pCNS | |
| Gene | TIMP1 | |
| Gene Description | TIMP metallopeptidase inhibitor 1 | |
| Clone sequence size | 896 (bp) | |
| Fullness | F | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 896 |
| Sequence | GAGTAATGCATCCAGGAAGCCTGGAGGCCTGTGGTTTCCGCACCC GCTGCCACCCCCGCCCCTAGCGTGGACATTTATCCTCTAGCGCTC AGGCCCTGCCGCCATCGCCGCAGATCCAGCGCCCAGAGAGACACC AGAGAACCCACCATGGCCCCCTTTGAGCCCCTGGCTTCTGGCATC CTGTTGTTGCTGTGGCTGATAGCCCCCAGCAGGGCCTGCACCTGT GTCCCACCCCACCCACAGACGGCCTTCTGCAATTCCGACCTCGTC ATCAGGGCCAAGTTCGTGGGGACACCAGAAGTCAACCAGACCACC TTATACCAGCGTTATGAGATCAAGATGACCAAGATGTATAAAGGG TTCCAAGCCTTAGGGGATGCCGCTGACATCCGGTTCGTCTACACC CCCGCCATGGAGAGTGTCTGCGGATACTTCCACAGGTCCCACAAC CGCAGCGAGGAGTTTCTCATTGCTGGAAAACTGCAGGATGGACTC TTGCACATCACTACCTGCAGTTTTGTGGCTCCCTGGAACAGCCTG AGCTTAGCTCAGCGCCGGGGCTTCACCAAGACCTACACTGTTGGC TGTGAGGAATGCACAGTGTTTCCCTGTTTATCCATCCCCTGCAAA CTGCAGAGTGGCACTCATTGCTTGTGGACGGACCAGCTCCTCCAA GGCTCTGAAAAGGGCTTCCAGTCCCGTCACCTTGCCTGCCTGCCT CGGGAGCCAGGGCTGTGCACCTGGCAGTCCCTGCGGTCCCAGATA GCCTGAATCCTGCCCGGAGTGGAAGCTGAAGCCTGCACAGTGTCC ACCCTGTTCCCACTCCCATCTTTCTTCCGGACAATGAAATAAAGA GTTACCACCCAGCAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | X | |||||||||||
| Location | Xp11.3-p11.23 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_003254 | |||||||||||
| KEGG Genes | 7076 | ||||||||||||
| GeneCard | TIMP1 |
| sequence | sequence of CDS | ATGGCCCCCTTTGAGCCCCTGGCTTCTGGCATCCTGTTGTTGCTGTGGCTGATAGCCCCCAGCAGGGCCTGCACCTGTGTCCCACCCCACCCACAGACGGCCTTCTGCAATTCCGACCTCGTCATCAGGGCCAAGTTCGTGGGGACACCAGAAGTCAACCAGACCACCTTATACCAGCGTTATGAGATCAAGATGACCAAGATGTATAAAGGGTTCCAAGCCTTAGGGGATGCCGCTGACATCCGGTTCGTCTACACCCCCGCCATGGAGAGTGTCTGCGGATACTTCCACAGGTCCCACAACCGCAGCGAGGAGTTTCTCATTGCTGGAAAACTGCAGGATGGACTCTTGCACATCACTACCTGCAGTTTTGTGGCTCCCTGGAACAGCCTGAGCTTAGCTCAGCGCCGGGGCTTCACCAAGACCTACACTGTTGGCTGTGAGGAATGCACAGTGTTTCCCTGTTTATCCATCCCCTGCAAACTGCAGAGTGGCACTCATTGCTTGTGGACGGACCAGCTCCTCCAAGGCTCTGAAAAGGGCTTCCAGTCCCGTCACCTTGCCTGCCTGCCTCGGGAGCCAGGGCTGTGCACCTGGCAGTCCCTGCGGTCCCAGATAGCCTGA |
| sequence of protein | MAPFEPLASGILLLLWLIAPSRACTCVPPHPQTAFCNSDLVIRAKFVGTPEVNQTTLYQRYEIKMTKMYKGFQALGDAADIRFVYTPAMESVCGYFHRSHNRSEEFLIAGKLQDGLLHITTCSFVAPWNSLSLAQRRGFTKTYTVGCEECTVFPCLSIPCKLQSGTHCLWTDQLLQGSEKGFQSRHLACLPREPGLCTWQSLRSQIA | |
| Database link | RefSeq | NM_003254 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008] |
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