Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | KU002102 |
| Korean Unigene Clone | UG-0001-H08 | |
| Original Clone | S1SNU5-6-E01 | |
| Vector | pCNS | |
| Gene | CDKN2C | |
| Gene Description | cyclin dependent kinase inhibitor 2C | |
| Clone sequence size | 2201 (bp) | |
| Fullness | F | |
| Mutation | Insertion | |
| Amino acid - mutation | ||
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 2201 |
| Sequence | CTCCTTAAAACTCTGCCGTTAAAATGGGGGCGGGTTTTTCAACTC AAAAAGCGCTCAATTTTTTTCTTTTCAAAAAAAGCTGATGAGGTC GGAAAAAAGGGAGAAGAAACCGGCACCCTCTCTGAGAGGCAACAG AAGCAGCAATTGTTTCAGCGAAAAAAGCAGCAAGGGAGGGAGTGA AGGAAAAAAGCAAAAAAGGGGGCGACACGCAAGTGCCTGTAGGGG TGAAAGGAGCAGGGACCGGCGATCTAGGGGGGGATCAGCTACAAA AGAAACTGTCACTGGGAGCGGTGCGGCCAAGGAGGAAGCAGTGCT GCCAGGCTCTGCTCCAGGGCACAGCTGGCTGGCGGCTGCCCTGTC CGCAGCAAAGGGGCACAGGCCGGGGACCGCGAGAGGTGGCAAAGT GGCACCGGGCGCCGAGGCTGCTGAGCGCTCGCCGAGACGGCGACC GGACTGGCTGCCCCGGAACTGCGGCGACTCTCCCTACTCAGAACT TGGCCTACGTTTCCCAGGACTCTCCCCATCTCCAGAGGCCCCCAC AAAACCGGGAAAGGAAGGAAAGGACAGCGGCGGCAGCAGCTCAAT GAGTGCCTACAGCAGAAAGCCTGAACGAGCTCGGTCGTAGGCGGG AAGTTCCCGGGGGGGCTGCCCAGTGCAGCCGCAATGCTGCCGCGA GCTGCCCCAGCAGTCCGGGCTCCGTAGACGCTTTCCGCATCACTC TCCTTCCTCGGGCTGCCGGGAGTCCCGGGACCTGGCGGGGCCGGC ATGACGGGCTTCTCGGGGGCCCGCCGCACGCCCGGCAGCCTCCGG AGACGCGCGCCGAGCCCGGCTCCCACGGCCTCTGAGGCTCGGCGG GGCTGCGGCTGCCTGGCGGGCGGGCTCCGGAGCTTTCCTGAGCGG CATTAGCCCACGGCTTGGCCCGGACGCGACCAAAGGCTCTTCTGG AGAAGCCCAGAGCACTGGGCAATCGTTACGACCTGTAACTTGAGG GCCACCGAACTGCTACTCCCGTTCGCCTTTGGCGATCATCTTTTA ACCCTCCGGAGCACGTCAGCATCCAGCCACCGCGGCGCTCTCCCA GCAGCGGAGGACCCAGGACTATCCCTTCGGCGAGACGGATGGAAA CCGAGCCCCCTGGAGGACCTGCCCCTGCAGTTCTGCCTCACACGG CTCAAGTCACCACCGTGAACTGCCCCTGCAGTTCTGCCTCACACG GCTCAAGTCACCACCGCTTTAAAGGGACCCTAAAGAATGGCCGAG CCTTGGGGGAACCAGTTGGCGTCCGCAGCTGCCAGGGGGGACCTA GAGCAACTTACTAGTTTGTTGCAAAATAATGTAAACGTCAATGCA CAAAATGGATTTGGAAGGACTGCGCTGCAGGTTATGAAACTTGGA AATCCCGAGATTGCCAGGAGACTGCTGCTACTTAGAGGTGCTAAT CCCGATTTGAAAGACCGAACTGGTTTCGCTGTCATTCATGATGCG GCCAGAGCAGGTTTCCTGGACACTTTACAGACTTTGCTGGAGTTT CAAGCTGATGTTAACATCGAGGATAATGAAGGGAACCTGCCCTTG CACTTGGCTGCCAAAGAAGGCCACCTCCGGGTGGTGGAGTTCCTG GTGAAGCACACGGCCAGCAATGTGGGGCATCGGAACCATAAGGGG GACACCGCCTGTGATTTGGCCAGGCTCTATGGGAGGAATGAGGTT GTTAGCCTGATGCAGGCAAACGGGGCTGGGGGAGCCACAAATCTT CAATAAACGTGGGGAGGGCTCCCCCACGTTGCCTCTACTTTATCA ATTAACTGAGTAGCTCTCCTGACTTTTAATGTCATTTGTTAAAAT ACAGTTCTGTCATATGTTAAGCAGCTAAATTTTCTGAAACTGCAT AAGTGAAAATCTTACAACAGGCTTATGAATATATTTAAGCAACAT CTTTTTAACCTGCAAAATCTGTTCTAACATGTAATTGCAGATAAC TTTGACTTTCTTCTGAATATTTTATCCTTTCCTTGGCTTTTCCCT TGCTTGAGACTTTGTTTTTAAAATGGTTTGTCCTGATGCTTTTGT CTAATTAAAACACTTTCAAAACAGGAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 1 | |||||||||||
| Location | 1p32 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_001262 | |||||||||||
| KEGG Genes | 1031 | ||||||||||||
| GeneCard | CDKN2C |
| sequence | sequence of CDS | ATGGCCGAGCCTTGGGGGAACGAGTTGGCGTCCGCAGCTGCCAGGGGGGACCTAGAGCAACTTACTAGTTTGTTGCAAAATAATGTAAACGTCAATGCACAAAATGGATTTGGAAGGACTGCGCTGCAGGTTATGAAACTTGGAAATCCCGAGATTGCCAGGAGACTGCTACTTAGAGGTGCTAATCCCGATTTGAAAGACCGAACTGGTTTCGCTGTCATTCATGATGCGGCCAGAGCAGGTTTCCTGGACACTTTACAGACTTTGCTGGAGTTTCAAGCTGATGTTAACATCGAGGATAATGAAGGGAACCTGCCCTTGCACTTGGCTGCCAAAGAAGGCCACCTCCGGGTGGTGGAGTTCCTGGTGAAGCACACGGCCAGCAATGTGGGGCATCGGAACCATAAGGGGGACACCGCCTGTGATTTGGCCAGGCTCTATGGGAGGAATGAGGTTGTTAGCCTGATGCAGGCAAACGGGGCTGGGGGAGCCACAAATCTTCAATAA |
| sequence of protein | MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ | |
| Database link | RefSeq | NM_001262 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008] |
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