Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | KU003416 |
| Korean Unigene Clone | UG-0095-G02 | |
| Original Clone | S13KMS5s1-1-F09 | |
| Vector | pCNS | |
| Gene | PLAUR | |
| Gene Description | plasminogen activator, urokinase receptor | |
| Clone sequence size | 1508 (bp) | |
| Fullness | F | |
| Mutation | Deletion | |
| Amino acid - mutation | ||
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 1508 |
| Sequence | AATTCGTATAACAAAACTGCCTCCTTCCTGAGGCCAGAAGGAGAG AAGACGTGCAGGGACCCCGCGCACAGGAGCTGCCCTCGCGACATG GGTCACCCGCCGCTGCTGCCGCTGCTGCTGCTGCTCCACACCTGC GTCCCAGCCTCTTGGGGCCTGCGGTGCATGCAGTGTAAGACCAAC GGGGATTGCCGTGTGGAAGAGTGCGCCCTGGGACAGGACCTCTGC AGGACCACGATCGTGCGCTTGTGGGAAGAAGGAGAAGAGCTGGAG CTGGTGGAGAAAAGCTGTACCCACTCAGAGAAGACCAACAGGACC CTGAGCTATCGGACTGGCTTGAAGATCACCAGCCTTACCGAGGTT GTGTGTGGGTTAGACTTGTGCAACCAGGGCAACTCTGGCCGGGCT GTCACCTATTCCCGAAGCCGTTACCTCGAATGCATTTCCTGTGGC TCATCAGACATGAGCTGTGAGAGGGGCCGGCACCAGAGCCTGCAG TGCCGCAGCCCTGAAGAACAGTGCCTGGATGTGGTGACCCACTGG ATCCAGGAAGGTGAAGAAGGGCGTCCAAAGGATGACCGCCACCTC CGTGGCTGTGGCTACCTTCCCGGCTGCCCGGGCTCCAATGGTTTC CACAACAACGACACCTTCCACTTCCTGAAATGCTGCAACACCACC AAATGCAACGAGGGCCCAATCCTGGAGCTTGAAAATCTGCCGCAG AATGGCCGCCAGTGTTACAGCTGCAAGGGGAACAGCACCCATGGA TGCTCCTCTGAAGAGACTTTCCTCATTGACTGCCGAGGCCCCATG AATCAATGTCTGGTAGCCACCGGCACTCACGAACCGAAAAACCAA AGCTATATGGTAAGAGGCTGTGCAACCGCCTCAATGTGCCAACAT GCCCACCTGGGTGACGCCTTCAGCATGAACCACATTGATGTCTCC TGCTGTACTAAAAGTGGCTGTAACCACCCAGACCTGGATGTCCAG TACCGCAGTGGGGCTGCTCCTCAGCCTGGCCCTGCCCATCTCAGC CTCACCATCACCCTGCTAATGACTGCCAGACTGTGGGGAGGCACT CTCCTCTGGACCTAAACCTGAAATCCCCCTCTCTGCCCTGGCTGG ATCCGGGGGACCCCTTTGCCCTTCCCTCGGCTCCCAGCCCTACAG ACTTGCTGTGTGACCTCAGGCCAGTGTGCCGACCTCTCTGGGCCT CAGTTTTCCCAGCTATGAAAACAGCTATCTCACAAAGTTGTGTGA AGCAGAAGAGAAAAGCTGGAGGAAGGCCGTGGGCCAATGGGAGAG CTCTTGTTATTATTAATATTGTTGCCGCTGTTGTGTTGTTGTTAT TAATTAATATTCATATTATTTATTTTATACTTACATAAAGATTTT GTACCAGTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 19 | |||||||||||
| Location | 19q13 | ||||||||||||
| Strand |
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| Database links | RefSeq | XM_011527028 | |||||||||||
| KEGG Genes | 5329 | ||||||||||||
| GeneCard | PLAUR |
| sequence | sequence of CDS | |
| sequence of protein | ||
| Database link | RefSeq | XM_011527028 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. [provided by RefSeq, Jul 2008] |
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