Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | KU005018 |
| Korean Unigene Clone | UG-0091-E04 | |
| Original Clone | S13KMS5-15-B01 | |
| Vector | pCNS | |
| Gene | MSLN | |
| Gene Description | mesothelin | |
| Clone sequence size | 2195 (bp) | |
| Fullness | F | |
| Mutation | 1979 | |
| Amino acid - mutation | CAA(Q)-> TAA(Stop) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 2195 |
| Sequence | CTTTCTGCCTGGCCGGCCACTCCCGTCTGCTGTGACGCGCGGACA GAGAGCTACCGGTGGACCCACGGTGCCTCCCTCCCTGGGATCTAC ACAGACCATGGCCTTGCCAACGGCTCGACCCCTGTTGGGGTCCTG TGGGACCCCCGCCCTCGGCAGCCTCCTGTTCCTGCTCTTCAGCCT CGGATGGGTGCAGCCCTCGAGGACCCTGGCTGGAGAGACAGGGCA GGAGGCTGCGCCCCTGGACGGAGTCCTGGCCAACCCACCTAACAT TTCCAGCCTCTCCCCTCGCCAACTCCTTGGCTTCCCGTGTGCGGA GGTGTCCGGCCTGAGCACGGAGCGTGTCCGGGAGCTGGCTGTGGC CTTGGCACAGAAGAATGTCAAGCTCTCAACAGAGCAGCTGCGCTG TCTGGCTCACCGGCTCTCTGAGCCCCCCGAGGACCTGGACGCCCT CCCATTGGACCTGCTGCTATTCCTCAACCCAGATGCGTTCTCGGG GCCCCAGGCCTGCACCCGTTTCTTCTCCCGCATCACGAAGGCCAA TGTGGACCTGCTCCCGAGGGGGGCTCCCGAGCGACAGCGGCTGCT GCCTGCGGCTCTGGCCTGCTGGGGTGTGCGGGGGTCTCTGCTGAG CGAGGCTGATGTGCGGGCTCTGGGAGGCCTGGCTTGCGACCTGCC TGGGCGCTTTGTGGCCGAGTCGGCCGAAGTGCTGCTACCCCGGCT GGTGAGCTGCCCGGGACCCCTGGACCAGGACCAGCAGGAGGCAGC CAGGGCGGCTCTGCAGGGCGGGGGACCCCCCTACGGCCCCCCGTC GACATGGTCTGTCTCCACGATGGACGCTCTGCGGGGCCTGCTGCC CGTGCTGGGCCAGCCCATCATCCGCAGCATCCCGCAGGGCATCGT GGCCGCGTGGCGGCAACGCTCCTCTCGGGACCCATCCTGGCGGCA GCCTGAACGGACCATCCTCCGGCCGCGGTTCCGGCGGGAAGTGGA GAAGACAGCCTGTCCTTCAGGCAAGAAGGCCCGCGAGATAGACGA GAGCCTCATCTTCTACAAGAAGTGGGAGCTGGAAGCCTGCGTGGA TGCGGCCCTGCTGGCCACCCAGATGGACCGCGTGAACGCCATCCC CTTCACCTACGAGCAGCTGGACGTCCTAAAGCATAAACTGGATGA GCTCTACCCACAAGGTTACCCCGAGTCTGTGATCCAGCACCTGGG CTACCTCTTCCTCAAGATGAGCCCTGAGGACATTCGCAAGTGGAA TGTGACGTCCCTGGAGACCCTGAAGGCTTTGCTTGAAGTCAACAA AGGGCACGAAATGAGTCCTCAGGTGGCCACCCTGATCGACCGCTT TGTGAAGGGAAGGGGCCAGCTAGACAAAGACACCCTAGACACCCT GACCGCCTTCTACCCTGGGTACCTGTGCTCCCTCAGCCCCGAGGA GCTGAGCTCCGTGCCCCCCAGCAGCATCTGGGCGGTCAGGCCCCA GGACCTGGACACGTGTGACCCAAGGCAGCTGGACGTCCTCTATCC CAAGGCCCGCCTTGCTTTCCAGAACATGAACGGGTCCGAATACTT CGTGAAGATCCAGTCCTTCCTGGGTGGGGCCCCCACGGAGGATTT GAAGGCGCTCAGTCAGCAGAATGTGAGCATGGACTTGGCCACGTT CATGAAGCTGCGGACGGATGCGGTGCTGCCGTTGACTGTGGCTGA GGTGCAGAAACTTCTGGGACCCCACGTGGAGGGCCTGAAGGCGGA GGAGCGGCACCGCCCGGTGCGGGACTGGATCCTACGGCAGCGGCA GGACGACCTGGACACGCTGGGGCTGGGGCTACAGGGCGGCATCCC CAACGGCTACCTGGTCCTAGACCTCAGCATGTAAGAGGCCCTCTC GGGGACGCCCTGCCTCCTAGGACCTGGACCTGTTCTCACCGTCCT GGCACTGCTCCTAGCCTCCACCCTGGCCTGAGGGCCCCACTCCCT TGCTGGCCCCAGCCCTGCTGGGGATCCCCGCCTGGCCAGGAGCAG GCACGGGTGGTCCCCGTTCCACCCCAAGAGAACTCGCGCTCAGTA AACGGGAACATGCCCCCTGCAGACAAAAAATAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 16 | |||||||||||
| Location | 16p13.3 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_005823 | |||||||||||
| KEGG Genes | 10232 | ||||||||||||
| GeneCard | MSLN |
| sequence | sequence of CDS | ATGGCCTTGCCAACGGCTCGACCCCTGTTGGGGTCCTGTGGGACCCCCGCCCTCGGCAGCCTCCTGTTCCTGCTCTTCAGCCTCGGATGGGTGCAGCCCTCGAGGACCCTGGCTGGAGAGACAGGGCAGGAGGCTGCGCCCCTGGACGGAGTCCTGGCCAACCCACCTAACATTTCCAGCCTCTCCCCTCGCCAACTCCTTGGCTTCCCGTGTGCGGAGGTGTCCGGCCTGAGCACGGAGCGTGTCCGGGAGCTGGCTGTGGCCTTGGCACAGAAGAATGTCAAGCTCTCAACAGAGCAGCTGCGCTGTCTGGCTCACCGGCTCTCTGAGCCCCCCGAGGACCTGGACGCCCTCCCATTGGACCTGCTGCTATTCCTCAACCCAGATGCGTTCTCGGGGCCCCAGGCCTGCACCCGTTTCTTCTCCCGCATCACGAAGGCCAATGTGGACCTGCTCCCGAGGGGGGCTCCCGAGCGACAGCGGCTGCTGCCTGCGGCTCTGGCCTGCTGGGGTGTGCGGGGGTCTCTGCTGAGCGAGGCTGATGTGCGGGCTCTGGGAGGCCTGGCTTGCGACCTGCCTGGGCGCTTTGTGGCCGAGTCGGCCGAAGTGCTGCTACCCCGGCTGGTGAGCTGCCCGGGACCCCTGGACCAGGACCAGCAGGAGGCAGCCAGGGCGGCTCTGCAGGGCGGGGGACCCCCCTACGGCCCCCCGTCGACATGGTCTGTCTCCACGATGGACGCTCTGCGGGGCCTGCTGCCCGTGCTGGGCCAGCCCATCATCCGCAGCATCCCGCAGGGCATCGTGGCCGCGTGGCGGCAACGCTCCTCTCGGGACCCATCCTGGCGGCAGCCTGAACGGACCATCCTCCGGCCGCGGTTCCGGCGGGAAGTGGAGAAGACAGCCTGTCCTTCAGGCAAGAAGGCCCGCGAGATAGACGAGAGCCTCATCTTCTACAAGAAGTGGGAGCTGGAAGCCTGCGTGGATGCGGCCCTGCTGGCCACCCAGATGGACCGCGTGAACGCCATCCCCTTCACCTACGAGCAGCTGGACGTCCTAAAGCATAAACTGGATGAGCTCTACCCACAAGGTTACCCCGAGTCTGTGATCCAGCACCTGGGCTACCTCTTCCTCAAGATGAGCCCTGAGGACATTCGCAAGTGGAATGTGACGTCCCTGGAGACCCTGAAGGCTTTGCTTGAAGTCAACAAAGGGCACGAAATGAGTCCTCAGGTGGCCACCCTGATCGACCGCTTTGTGAAGGGAAGGGGCCAGCTAGACAAAGACACCCTAGACACCCTGACCGCCTTCTACCCTGGGTACCTGTGCTCCCTCAGCCCCGAGGAGCTGAGCTCCGTGCCCCCCAGCAGCATCTGGGCGGTCAGGCCCCAGGACCTGGACACGTGTGACCCAAGGCAGCTGGACGTCCTCTATCCCAAGGCCCGCCTTGCTTTCCAGAACATGAACGGGTCCGAATACTTCGTGAAGATCCAGTCCTTCCTGGGTGGGGCCCCCACGGAGGATTTGAAGGCGCTCAGTCAGCAGAATGTGAGCATGGACTTGGCCACGTTCATGAAGCTGCGGACGGATGCGGTGCTGCCGTTGACTGTGGCTGAGGTGCAGAAACTTCTGGGACCCCACGTGGAGGGCCTGAAGGCGGAGGAGCGGCACCGCCCGGTGCGGGACTGGATCCTACGGCAGCGGCAGGACGACCTGGACACGCTGGGGCTGGGGCTACAGGGCGGCATCCCCAACGGCTACCTGGTCCTAGACCTCAGCATGCAAGAGGCCCTCTCGGGGACGCCCTGCCTCCTAGGACCTGGACCTGTTCTCACCGTCCTGGCACTGCTCCTAGCCTCCACCCTGGCCTGA |
| sequence of protein | MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISSLSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPLDLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTWSVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKTACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELYPQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLSMQEALSGTPCLLGPGPVLTVLALLLASTLA | |
| Database link | RefSeq | NM_005823 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016] |
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