Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | KU035253 |
| Korean Unigene Clone | UG-0366-H05 | |
| Original Clone | S10SNU1-18-C07 | |
| Vector | pME18S-FL3 | |
| Gene | PON2 | |
| Gene Description | paraoxonase 2 | |
| Clone sequence size | 1654 (bp) | |
| Fullness | F | |
| Mutation | Insertion | |
| Amino acid - mutation | ||
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 1654 |
| Sequence | AAGATGGCACCGCCCACGGAGCTGCTGGCCAGGCCGGAGCGAGGC AGCGCGCCCGGCTCCCGCGCCATGGGGCGGCTGGTGGCTGTGGGC TTGCTGGGGATCGCGCTGGCGCTCCTGGGCGAGAGGCTTCTGGCA CTCAGAAATCGACTTAAAGCCTCCAGAGAAGTAGAATCTGTAGAC CTTCCACACTGCCACCTGATTAAAGGAATTGAAGCTGGCTCTGAA GATATTGACATACTTCCCAATGGTCTGGCTTTTTTTAGTGTGGGT CTAAAATTCCCAGGACTCCACAGCTTTGCACCAGATAAGCCTGGA GGAATACTAATGATGGATCTAAAAGAAGAAAAACCAAGGGCACGG GAATTAAGAATCAGTCGTGGGTTTGATTTGGCCTCATTCAATCCA CATGGCATCAGCACTTTCATAGACAACGAATTCAAGAATACAGTG GAAATTTTTAAATTTGAAGAAGCAGAAAATTCTCTGTTGCATCTG AAAACAGTCAAACATGAGCTTCTTCCAAGTGTGAATGACATCACA GCTGTTGGACCGGCACATTTCTATGCCACAAATGACCACTACTTC TCTGATCCTTTCTTAAAGTATTTAGAAACATACTTGAACTTACAC TGGGGCAAATGTTGTTTACTACAGTCCAAATGAAGTTAAAGTGGT AGCAGAAGGATTTGATTCAGCAAATGGGATCAATATTTCACCTGA TGATAAGTATATCTATGTTGCTGACATATTGGCTCATGAAATTCA TGTTTTGGAAAAACACACTAATATGAATTTAACTCAGTTGAAGGT ACTTGAGCTGGATACACTGGTGGATAATTTATCTATTGATCCTTC CTCGGGGGACATCTGGGTAGGCTGTCATCCTAATGGCCAGAAGCT CTTCGTGTATGACCCGAACAATCCTCCCTCGTCAGAGGTTCTCCG CATCCAGAACATTCTATCTGAGAAGCCTACAGTGACTACAGTTTA TGCCAACAATGGGTCTGTTCTCCAAGGAAGTTCTGTAGCCTCAGT GTATGATGGGAAGCTGCTCATAGGCACTTTATACCACAGAGCCTT GTATTGTGAACTCTAAATTGTACTTTTGGCATGAAAGTGCGATAA CTTAACAATTAATTTTCTATGAATTGCTAATTCTGAGGGAATTTA ACCAGCAACATTGACCCAGAAATGTATGGCATGTGTAGTTAATTT TATTCCAGTAAGGAACGGCCCTTTTAGTTCTTAGAGCACTTTTAA CAAAAAAGGAAAATGAACAGGTTCTTTAAAATGCCAAGCAAGGGA CAGAAAAGAAAGCTGCTTTCGAATAAAGTGAATACATTTTGCACA AAGTAAGCCTCACCTTTGCCTTCCAACTGCCAGAACATGGATTCC ACTGAAATAGAGTGAATTATATTTCCTTAAAATGTGAGTGACCTC ACTTCTGGCACTGTGACTACTATGGCTGTTTAGAACTACTGATTT TCCTTAAAATGTGAGTGACCTCACTTCTGGCACTGTGACTACTAT GGCTGTTTAGAACTACTGATAATAACGTATTTTGATGTTTTGTAC TTACATCTTTGTTTACCATTAAAAAGTTGGAGTTATATTAAAGAC TAACTAAAATCCCAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 7 | |||||||||||
| Location | 7q21.3 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_001018161 | |||||||||||
| KEGG Genes | 5445 | ||||||||||||
| GeneCard | PON2 |
| sequence | sequence of CDS | ATGGGGCGGCTGGTGGCTGTGGGCTTGCTGGGGATCGCGCTGGCGCTCCTGGGCGAGAGGCTTCTGGCACTCAGAAATCGACTTAAAGCCTCCAGAGAAGTAGAATCTGTAGACCTTCCACACTGCCACCTGATTAAAGGAATTGAAGCTGGCTCTGAAGATATTGACATACTTCCCAATGGTCTGGCTTTTTTTAGTGTGGGTCTAAAATTCCCAGGACTCCACAGCTTTGCACCAGATAAGCCTGGAGGAATACTAATGATGGATCTAAAAGAAGAAAAACCAAGGGCACGGGAATTAAGAATCAGTCGTGGGTTTGATTTGGCCTCATTCAATCCACATGGCATCAGCACTTTCATAGACAACGAATTCAAGAATACAGTGGAAATTTTTAAATTTGAAGAAGCAGAAAATTCTCTGTTGCATCTGAAAACAGTCAAACATGAGCTTCTTCCAAGTGTGAATGACATCACAGCTGTTGGACCGGCACATTTCTATGCCACAAATGACCACTACTTCTCTGATCCTTTCTTAAAGTATTTAGAAACATACTTGAACTTACACTGGGCAAATGTTGTTTACTACAGTCCAAATGAAGTTAAAGTGGTAGCAGAAGGATTTGATTCAGCAAATGGGATCAATATTTCACCTGATGATAAGTATATCTATGTTGCTGACATATTGGCTCATGAAATTCATGTTTTGGAAAAACACACTAATATGAATTTAACTCAGTTGAAGGTACTTGAGCTGGATACACTGGTGGATAATTTATCTATTGATCCTTCCTCGGGGGACATCTGGGTAGGCTGTCATCCTAATGGCCAGAAGCTCTTCGTGTATGACCCGAACAATCCTCCCTCGTCAGAGGTTCTCCGCATCCAGAACATTCTATCTGAGAAGCCTACAGTGACTACAGTTTATGCCAACAATGGGTCTGTTCTCCAAGGAAGTTCTGTAGCCTCAGTGTATGATGGGAAGCTGCTCATAGGCACTTTATACCACAGAGCCTTGTATTGTGAACTCTAA |
| sequence of protein | MGRLVAVGLLGIALALLGERLLALRNRLKASREVESVDLPHCHLIKGIEAGSEDIDILPNGLAFFSVGLKFPGLHSFAPDKPGGILMMDLKEEKPRARELRISRGFDLASFNPHGISTFIDNEFKNTVEIFKFEEAENSLLHLKTVKHELLPSVNDITAVGPAHFYATNDHYFSDPFLKYLETYLNLHWANVVYYSPNEVKVVAEGFDSANGINISPDDKYIYVADILAHEIHVLEKHTNMNLTQLKVLELDTLVDNLSIDPSSGDIWVGCHPNGQKLFVYDPNNPPSSEVLRIQNILSEKPTVTTVYANNGSVLQGSSVASVYDGKLLIGTLYHRALYCEL | |
| Database link | RefSeq | NM_001018161 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008] |
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