Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hIU006981 |
| Korean Unigene Clone | 21-4-A-F06 | |
| Original Clone | INCYTE:2182901 | |
| Vector | pINCY | |
| Gene | DEFA6 | |
| Gene Description | defensin alpha 6 | |
| Clone sequence size | 456 (bp) | |
| Fullness | F | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 456 |
| Sequence | CAGCGACCCTAGCCATGAGAACCCTCACCATCCTCACTGCTGTTC TCCTCGTGGCCCTCCAGGCCAAGGCTGAGCCACTCCAAGCTGAGG ATGATCCACTGCAGGCAAAAGCTTATGAGGCTGATGCCCAGGAGC AGCGTGGGGCAAATGACCAGGACTTTGCCGTCTCCTTTGCAGAGG ATGCAAGCTCAAGTCTTAGAGCTTTGGGCTCAACAAGGGCTTTCA CTTGCCATTGCAGAAGGTCCTGTTATTCAACAGAATATTCCTATG GGACCTGCACTGTCATGGGTATTAACCACAGATTCTGCTGCCTCT GAGGGATGAGAACAGAGAGAAATATATTCATAATTTACTTTATGA CCTAGAAGGAAACTGTCGTGTGTCCCATACATTGCCATCAACTTT GTTTCCTCATCTCAAATAAAGTCCTTTCAGCAAGTTAAAAAAAAA AAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 8 | |||||||||||
| Location | 8p23.1 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_001926 | |||||||||||
| KEGG Genes | 1671 | ||||||||||||
| GeneCard | DEFA6 |
| sequence | sequence of CDS | ATGAGAACCCTCACCATCCTCACTGCTGTTCTCCTCGTGGCCCTCCAGGCCAAGGCTGAGCCACTCCAAGCTGAGGATGATCCACTGCAGGCAAAAGCTTATGAGGCTGATGCCCAGGAGCAGCGTGGGGCAAATGACCAGGACTTTGCCGTCTCCTTTGCAGAGGATGCAAGCTCAAGTCTTAGAGCTTTGGGCTCAACAAGGGCTTTCACTTGCCATTGCAGAAGGTCCTGTTATTCAACAGAATATTCCTATGGGACCTGCACTGTCATGGGTATTAACCACAGATTCTGCTGCCTCTGA |
| sequence of protein | MRTLTILTAVLLVALQAKAEPLQAEDDPLQAKAYEADAQEQRGANDQDFAVSFAEDASSSLRALGSTRAFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL | |
| Database link | RefSeq | NM_001926 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 6, is highly expressed in the secretory granules of Paneth cells of the small intestine, and likely plays a role in host defense of human bowel. [provided by RefSeq, Oct 2014] |
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