Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU000854 |
| Korean Unigene Clone | IRAT-09-H02 | |
| Original Clone | IRAK-14-G15 | |
| Vector | pCMV-SPORT6 | |
| Gene | SERPINE1 | |
| Gene Description | serpin family E member 1 | |
| Clone sequence size | 2207 (bp) | |
| Fullness | F | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 2207 |
| Sequence | GGCCAAGAGCGCTGTCAAGAAGACCCACACGCCCCCCTCCAGCAG CTGAATTCCTGCAGCTCAGCAGCCGCCGCCAGAGCAGGACGAACC GCCAATCGCAAGGCACCTCTGAGAACTTCAGGATGCAGATGTCTC CAGCCCTCACCTGCCTAGTCCTGGGCCTGGCCCTTGTCTTTGGTG AAGGGTCTGCTGTGCACCATCCCCCATCCTACGTGGCCCACCTGG CCTCAGACTTCGGGGTGAGGGTGTTTCAGCAGGTGGCGCAGGCCT CCAAGGACCGCAACGTGGTTTTCTCACCCTATGGGGTGGCCTCGG TGTTGGCCATGCTCCAGCTGACAACAGGAGGAGAAACCCAGCAGC AGATTCAAGCAGCTATGGGATTCAAGATTGATGACAAGGGCATGG CCCCCGCCCTCCGGCATCTGTACAAGGAGCTCATGGGGCCATGGA ACAAGGATGAGATCAGCACCACAGACGCGATCTTCGTCCAGCGGG ATCTGAAGCTGGTCCAGGGCTTCATGCCCCACTTCTTCAGGCTGT TCCGGAGCACGGTCAAGCAAGTGGACTTTTCAGAGGTGGAGAGAG CCAGATTCATCATCAATGACTGGGTGAAGACACACACAAAAGGTA TGATCAGCAACTTGCTTGGGAAAGGAGCCGTGGACCAGCTGACAC GGCTGGTGCTGGTGAATGCCCTCTACTTCAACGGCCAGTGGAAGA CTCCCTTCCCCGACTCCAGCACCCACCGCCGCCTCTTCCACAAAT CAGACGGCAGCACTGTCTCTGTGCCCATGATGGCTCAGACCAACA AGTTCAACTATACTGAGTTCACCACGCCCGATGGCCATTACTACG ACATCCTGGAACTGCCCTACCACGGGGACACCCTCAGCATGTTCA TTGCTGCCCCTTATGAAAAAGAGGTGCCTCTCTCTGCCCTCACCA ACATTCTGAGTGCCCAGCTCATCAGCCACTGGAAAGGCAACATGA CCAGGCTGCCCCGCCTCCTGGTTCTGCCCAAGTTCTCCCTGGAGA CTGAAGTCGACCTCAGGAAGCCCCTAGAGAACCTGGGAATGACCG ACATGTTCAGACAGTTTCAGGCTGACTTCACGAGTCTTTCAGACC AAGAGCCTCTCCACGTCGCGCAGGCGCTGCAGAAAGTGAAGATCG AGGTGAACGAGAGTGGCACGGTGGCCTCCTCATCCACAGCTGTCA TAGTCTCAGCCCGCATGGCCCCCGAGGAGATCATCATGGACAGAC CCTTCCTCTTTGTGGTCCGGCACAACCCCACAGGAACAGTCCTTT TCATGGGCCAAGTGATGGAACCCTGACCCTGGGGAAAGACGCCTT CATCTGGGACAAAACTGGAGATGCATCGGGAAAGAAGAAACTCCG AAGAAAAGAATTTTAGTGTTAATGACTCTTTCTGAAGGAAGAGAA GACATTTGCCTTTTGTTAAAAGATGGTAAACCAGATCTGTCTCCA AGACCTTGGCCTCTCCTTGGAGGACCTTTAGGTCAAACTCCCTAG TCTCCACCTGAGACCCTGGGAGAGAAGTTTGAAGCACAACTCCCT TAAGGTCTCCAAACCAGACGGTGACGCCTGCGGGACCATCTGGGG CACCTGCTTCCACCCGTCTCTCTGCCCACTCGGGTCTGCAGACCT GGTTCCCACTGAGGCCCTTTGCAGGACGGAACTACGGGGCTTACA GGAGCTTTTGTGTGCCTGGTAGAAACTATTTCTGTTCCAGTCACA TTGCCATCACTCTTGTACTGCCTGCCACCGCGGAGGAGGCTGGTG ACAGGCCAAAGGCCAGTGGAAGAAACACCCTTTCATCTCAGAGTC CACTGTGGCACTGGCCACCCCTCCCCAGTACAGGGGTGCTGCAGG TGGCAGAGTGAATGTCCCCCATCATGTGGCCCAACTCTCCTGGCC TGGCCATCTCCCTCCCCAGAAACAGTGTGCATGGGTTATTTTGGA GTGTAGGTGACTTGTTTACTCATTGAAGCAGATTTCTGCTTCCTT TTATTTTTATAGGAATAGAGGAAGAAAGGTCAGATGCGTGCCCAG CTCTTCACCCCCCAATCTCTTGGTGGGGAGGGGTGTACCTAAATA TTTATCATATCCTTGCCCTTGAGTGCTTGTTAGAGAGAAAGAGAA CTACTAAGGAAAATAATATTATTTAAACTCGCAAAAAAAAAAAAA AA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 7 | |||||||||||
| Location | 7q22.1 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_000602 | |||||||||||
| KEGG Genes | 5054 | ||||||||||||
| GeneCard | SERPINE1 |
| sequence | sequence of CDS | ATGCAGATGTCTCCAGCCCTCACCTGCCTAGTCCTGGGCCTGGCCCTTGTCTTTGGTGAAGGGTCTGCTGTGCACCATCCCCCATCCTACGTGGCCCACCTGGCCTCAGACTTCGGGGTGAGGGTGTTTCAGCAGGTGGCGCAGGCCTCCAAGGACCGCAACGTGGTTTTCTCACCCTATGGGGTGGCCTCGGTGTTGGCCATGCTCCAGCTGACAACAGGAGGAGAAACCCAGCAGCAGATTCAAGCAGCTATGGGATTCAAGATTGATGACAAGGGCATGGCCCCCGCCCTCCGGCATCTGTACAAGGAGCTCATGGGGCCATGGAACAAGGATGAGATCAGCACCACAGACGCGATCTTCGTCCAGCGGGATCTGAAGCTGGTCCAGGGCTTCATGCCCCACTTCTTCAGGCTGTTCCGGAGCACGGTCAAGCAAGTGGACTTTTCAGAGGTGGAGAGAGCCAGATTCATCATCAATGACTGGGTGAAGACACACACAAAAGGTATGATCAGCAACTTGCTTGGGAAAGGAGCCGTGGACCAGCTGACACGGCTGGTGCTGGTGAATGCCCTCTACTTCAACGGCCAGTGGAAGACTCCCTTCCCCGACTCCAGCACCCACCGCCGCCTCTTCCACAAATCAGACGGCAGCACTGTCTCTGTGCCCATGATGGCTCAGACCAACAAGTTCAACTATACTGAGTTCACCACGCCCGATGGCCATTACTACGACATCCTGGAACTGCCCTACCACGGGGACACCCTCAGCATGTTCATTGCTGCCCCTTATGAAAAAGAGGTGCCTCTCTCTGCCCTCACCAACATTCTGAGTGCCCAGCTCATCAGCCACTGGAAAGGCAACATGACCAGGCTGCCCCGCCTCCTGGTTCTGCCCAAGTTCTCCCTGGAGACTGAAGTCGACCTCAGGAAGCCCCTAGAGAACCTGGGAATGACCGACATGTTCAGACAGTTTCAGGCTGACTTCACGAGTCTTTCAGACCAAGAGCCTCTCCACGTCGCGCAGGCGCTGCAGAAAGTGAAGATCGAGGTGAACGAGAGTGGCACGGTGGCCTCCTCATCCACAGCTGTCATAGTCTCAGCCCGCATGGCCCCCGAGGAGATCATCATGGACAGACCCTTCCTCTTTGTGGTCCGGCACAACCCCACAGGAACAGTCCTTTTCATGGGCCAAGTGATGGAACCCTGA |
| sequence of protein | MQMSPALTCLVLGLALVFGEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAMGFKIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRLLVLPKFSLETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIVSARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP | |
| Database link | RefSeq | NM_000602 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] |
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