Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU001599 |
| Korean Unigene Clone | IRAT-17-F03 | |
| Original Clone | IRAK-22-B10 | |
| Vector | pCMV-SPORT6 | |
| Gene | IL6 | |
| Gene Description | interleukin 6 | |
| Clone sequence size | 1127 (bp) | |
| Fullness | F | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 1127 |
| Sequence | CCCACCGGGAACGAAAGAGAAGCTCTATCTCCCCTCCAGGAGCCC AGCTATGAACTCCTTCTCCACAAGCGCCTTCGGTCCAGTTGCCTT CTCCCTGGGGCTGCTCCTGGTGTTGCCTGCTGCCTTCCCTGCCCC AGTACCCCCAGGAGAAGATTCCAAAGATGTAGCCGCCCCACACAG ACAGCCACTCACCTCTTCAGAACGAATTGACAAACAAATTCGGTA CATCCTCGACGGCATCTCAGCCCTGAGAAAGGAGACATGTAACAA GAGTAACATGTGTGAAAGCAGCAAAGAGGCACTGGCAGAAAACAA CCTGAACCTTCCAAAGATGGCTGAAAAAGATGGATGCTTCCAATC TGGATTCAATGAGGAGACTTGCCTGGTGAAAATCATCACTGGTCT TTTGGAGTTTGAGGTATACCTAGAGTACCTCCAGAACAGATTTGA GAGTAGTGAGGAACAAGCCAGAGCTGTGCAGATGAGTACAAAAGT CCTGATCCAGTTCCTGCAGAAAAAGGCAAAGAATCTAGATGCAAT AACCACCCCTGACCCAACCACAAATGCCAGCCTGCTGACGAAGCT GCAGGCACAGAACCAGTGGCTGCAGGACATGACAACTCATCTCAT TCTGCGCAGCTTTAAGGAGTTCCTGCAGTCCAGCCTGAGGGCTCT TCGGCAAATGTAGCATGGGCACCTCAGATTGTTGTTGTTAATGGG CATTCCTTCTTCTGGTCAGAAACCTGTCCACTGGGCACAGAACTT ATGTTGTTCTCTATGGAGAACTAAAAGTATGAGCGTTAGGACACT ATTTTAATTATTTTTAATTTATTAATATTTAAATATGTGAAGCTG AGTTAATTTATGTAAGTCATATTTATATTTTTAAGAAGTACCACT TGAAACATTTTATGTATTAGTTTTGAAATAATAATGGAAAGTGGC TATGCAGTTTGAATATCCTTTGTTTCAGAGCCAGATCATTTCTTG GAAAGTGTAGGCTTACCTCAAATAAATGGCTAACTTATACATATT TTTAAAGAAATATTTATATTGTATTTATATAATGTATAAATGGTT TTTATACCAATAAATGGCATTTTAAAAAATTCAAAAAAAAAAAAA AA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 7 | |||||||||||
| Location | 7p21 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_000600 | |||||||||||
| KEGG Genes | 3569 | ||||||||||||
| GeneCard | IL6 |
| sequence | sequence of CDS | ATGAACTCCTTCTCCACAAGCGCCTTCGGTCCAGTTGCCTTCTCCCTGGGGCTGCTCCTGGTGTTGCCTGCTGCCTTCCCTGCCCCAGTACCCCCAGGAGAAGATTCCAAAGATGTAGCCGCCCCACACAGACAGCCACTCACCTCTTCAGAACGAATTGACAAACAAATTCGGTACATCCTCGACGGCATCTCAGCCCTGAGAAAGGAGACATGTAACAAGAGTAACATGTGTGAAAGCAGCAAAGAGGCACTGGCAGAAAACAACCTGAACCTTCCAAAGATGGCTGAAAAAGATGGATGCTTCCAATCTGGATTCAATGAGGAGACTTGCCTGGTGAAAATCATCACTGGTCTTTTGGAGTTTGAGGTATACCTAGAGTACCTCCAGAACAGATTTGAGAGTAGTGAGGAACAAGCCAGAGCTGTGCAGATGAGTACAAAAGTCCTGATCCAGTTCCTGCAGAAAAAGGCAAAGAATCTAGATGCAATAACCACCCCTGACCCAACCACAAATGCCAGCCTGCTGACGAAGCTGCAGGCACAGAACCAGTGGCTGCAGGACATGACAACTCATCTCATTCTGCGCAGCTTTAAGGAGTTCCTGCAGTCCAGCCTGAGGGCTCTTCGGCAAATGTAG |
| sequence of protein | MNSFSTSAFGPVAFSLGLLLVLPAAFPAPVPPGEDSKDVAAPHRQPLTSSERIDKQIRYILDGISALRKETCNKSNMCESSKEALAENNLNLPKMAEKDGCFQSGFNEETCLVKIITGLLEFEVYLEYLQNRFESSEEQARAVQMSTKVLIQFLQKKAKNLDAITTPDPTTNASLLTKLQAQNQWLQDMTTHLILRSFKEFLQSSLRALRQM | |
| Database link | RefSeq | NM_000600 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015] |
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