Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU002412 |
| Korean Unigene Clone | IRAT-26-A12 | |
| Original Clone | IRAK-33-P14 | |
| Vector | pBluescriptR | |
| Gene | ACE | |
| Gene Description | angiotensin I converting enzyme | |
| Clone sequence size | 4874 (bp) | |
| Fullness | F | |
| Mutation | Large_Deletion | |
| Amino acid - mutation | ||
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 4874 |
| Sequence | ATTGGCCAGGGGACGGTAGCTGCAGGACTCTGCTCTCCTGCGGCC ATGGGCCAGGGTTGGGCTACTGCAGGACTTCCCAGCCTCCTCTTC CTGCTGCTCTGCTACGGGCACCCTCTGCTGGTCCCTAGCCAGGAG GCATCCCAACAGGTGACAGTCACCCATGGGACAAGCAGCCAGGCA ACAACCAGCAGCCAGACAACCACCCACCAGGCGACGGCCCACCAG GCATCAGCCCAGAGCCCAAACCTGGTGACTGATGAGGCTGAGGCC AGCAAGTTTGTGGAGGAATATGACCGGACATCCCAGGTGGTGTGG AACGAGTATGCCGAGGCCAACTGGAACTACAACACCAACATCACC ACAGAGACCAGCAAGATTCTGCTGCAGAAGAACATGCAAATAGCC AACCACACCCTGAAGTACGGCACCCAGGCCAGGAAGTTTGATGTG AACCAGTTGCAGAACACCACTATCAAGCGGATCATAAAGAAGGTT CAGGACCTAGAACGGGCAGCGCTGCCTGCCCAGGAGCTGGAGGAG TACAACAAGATCCTGTTGGATATGGAAACCACCTACAGCGTGGCC ACTGTGTGCCACCCGAATGGCAGCTGCCTGCAGCTCGAGCCAGAT CTGACGAATGTGATGGCCACATCCCGGAAATATGAAGACCTGTTA TGGGCATGGGAGGGCTGGCGAGACAAGGCGGGGAGAGCCATCCTC CAGTTTTACCCGAAATACGTGGAACTCATCAACCAGGCTGCCCGG CTCAATGGCTATGTAGATGCAGGGGACTCGTGGAGGTCTATGTAC GAGACACCATCCCTGGAGCAAGACCTGGAGCGGCTCTTCCAGGAG CTGCAGCCACTCTACCTCAACCTGCATGCCTACGTGCGCCGGGCC CTGCACCGTCACTACGGGGCCCAGCACATCAACCTGGAGGGGCCC ATTCCTGCTCACCTGCTGGGGAACATGTGGGCGCAGACCTGGTCC AACATCTATGACTTGGTGGTGCCCTTCCCTTCAGCCCCCTCGATG GACACCACAGAGGCTATGCTAAAGCAGGGCTGGACGCCCAGGAGG ATGTTTAAGGAGGCTGATGATTTCTTCACCTCCCTGGGGCTGCTG CCCGTGCCTCCTGAGTTCTGGAACAAGTCGATGCTGGAGAAGCCA ACCGACGGGCGGGAGGTGGTCTGCCACGCCTCGGCCTGGGACTTC TACAACGGCAAGGACTTCCGGATCAAGCAGTGCACCACCGTGAAC TTGGAGGACCTGGTGGTGGCCCACCACGAAATGGGCCACATCCAG TATTTCATGCAGTACAAAGACTTACCTGTGGCCTTGAGGGAGGGT GCCAACCCCGGCTTCCATGAGGCCATTGGGGACGTGCTAGCCCTC TCAGTGTCTACGCCCAAGCACCTGCACAGTCTCAACCTGCTGAGC AGTGAGGGTGGCAGCGACGAGCATGACATCAACTTTCTGATGAAG ATGGCCCTTGACAAGATCGCCTTTATCCCCTTCAGCTACCTCGTC GATCAGTGGCGCTGGAGGGTATTTGATGGAAGCATCACCAAGGAG AACTATAACCAGGAGTGGTGGAGCCTCAGGCTGAAGTACCAGGGC CTCTGCCCCCCAGTGCCCAGGACTCAAGGTGACTTTGACCCAGGG GCCAAGTTCCACATTCCTTCTAGCGTGCCTTACATCAGGTACTTC GTCAGCTTCATCATCCAGTTCCAGTTCCACGAGGCACTGTGCCAG GCAGCTGGCCACACGGGCCCCCTGCACAAGTGTGACATCTACCAG TCCAAGGAGGCCGGGCAGCGCCTGGCGACCGCCATGAAGCTGGGC TTCAGTAGGCCGTGGCCGGAAGCCATGCAGCTGATCACGGGCCAG CCCAACATGAGCGCCTCGGCCATGTTGAGCTACTTCAAGCCGCTG CTGGACTGGCTCCGCACGGAGAACGAGCTGCATGGGGAGAAGCTG GGCTGGCCGCAGTACAACTGGACGCCGAACTCCGATGACTTCTAC AATGAGACCGAGACCAAGATCTTCCTGCAGTTTTATGACCAAACA GGGATTTGGGACCATGGGGCACCACATCTCCTGCCCCCATCCCAA GCAAGAGGAACAAGGGAAGCCCCAGTGTACATGTCAAAGAGGGCT GCAAGCTCTGGGCCTCCTGGAAGCCCTAAACTTCCTCCAGCTGCA CAAGGACATGGAGAGGTCCCAGTTCATGATTTACTTTGGCACCCA GGCCCACCTGTTTAAAGTCACCCAGTTCAAGGACCCGGATGTGAA TGGCATGCTGAAACTCGAAGTCATGGCCACCTCCAGGGACAAAGA GGAGCTGCTGTGGGCCTGGCAGGGCTGGCAGGATGCCGTGGGCCG CCAGATCTGCACCACCTTCGAGCACTATGTGGAGCTCAGCAACAA GGCTGCACAGCTCAACGGAAGAGGCTGCTGAGAAAGAGAATGAGA AGAGGCTGCTGCAGACAAGTGGACAGGGAAGGCCTCTGACATTTA TCCAAGACCTGAAAGATGGGCAAAAGACGGGAAGCAAGATGTGAA AGAAGAGCAGCCTAGGCAGAGGCTCCGCGGCAGGAGGAGCCGGTG CTCTGGAAGACCTGAAAGAAGCCCAGGTTACAAAGACATGGGGGC CTTGTGGCACTCCAAGTATGAGTCGGATACCCTGGAGCAAGACCT GGAGCGGCTATTCCAGGAGCTGCGGCCACTCTACCTGAACCTGCA CACCTACGTGCGCAGGGCCCTCCACCGCCACTATGGGCCCGAGCT CATCGACCTGAGGGGGCCCATCCCTGCCCACCTCCTGGAGAACAC GTTGGCTCAGTCCTGGGTCAACATCTTAGACCCGGTCCTGCCCTT CCTGAAGAAGATCCCAGAGGATGTCACAAAGATCATGAAAGTCCA GCACTGGAAGCCAGAGAAAATGTTGGAAGAGGCTGAGACATTCTT CACCTCCTTGGCGCTGCCACCTGCCCCACCCAGTTTCTGGAAAAA GTTGATGCTAATGAGGCCAACCGATGGGCGAGAGGTGGAGTGTCA CATCTCTGCCTGGAACTTCTACCAGGACGACGATTTCAGCTAGGA GGCTGAGGCAGGAGAATCACTGGAACCTGGGAGCCGGAGGCTGCA GTGAGCCAAGATCGCACCATTGCACTCCAGCTGGGAGACACAGCA AGACTCCGTCTCAAAAGAAAAAAAAAAAAAAGAACAACTGCCAAG AATAAAGAAGTGCGCGGAAGTGACCACAGAAGACCCGCTCTCCAT CTTCCACGAAATGGGCCATTCCAGTACTTCCTGCAGTACAAGAAC CTCTCCATCATCTTCCGCGCAGGTGCCAACCCAGCCTTTGAAGAG GCTGTGGGGTCTGTGATCACCCTCTCGGCCTCCTCCCACAAGCAC CTGCTCAACATAGGCCTGCTCAGCCTCTAGCACCAGGACTCAGAG GATGAGGTCAATTTCCTGATGCATATTGCCCTGGAGAAGATCGCC TTCATCCCCTTTGGCTACCTGATGGACCTCCTTCGCTGGAAGGTC TTTGACGGCACCATCTGGAAGGACATCTACAATCAGGAGTGGTGG AACCTCAGGTTGAAATACCAGGGCTTGTGCCCCGCTATTCCTCAC TCAGAGGAAGACTTTGATCCAGGTGCCAAGTTCCACTTTTCTGCA GGTACTTCCTCAGTCTGGTGCTCCAGTTCCAGTTCCACGAAACAC TGTGCAAAGCCTCGGGCCACATGGGTCCACTGCACCAGTGTGACA TCTACAACTCCAAGATTGCCGGGAAGCTCCTGGGGGATGCTCTAA AGCTGGGCTCAAGCAAGCCCTGGCCAGAGGTCCTAAAGATGCTGA CTGGGGAGTCTGAGGTGTCTACAAATGTCTTCATGACCTACTTCA AACCCCTACTGACCTGGCTGGTGACAGAACATGCAGCAAGGGGAC ATCTTAGGCTGGCCAGACTTCAGCTGTTCCTTTGAAGAAAAAGAC ACAGACAAAGTGACATTCCTGAGTCTGAAGCTGGACCCCAACCAG GCTAAATTTGGGTACTGGGTGCTGTTGGCCCTGGGCTTTGTCATG TCTCTGGTGGTGCTGGGGCTGGCCTGCAGGCTGCAGTCCCTGGAA AAACAGTCACTGACTCAAGACACTGAGATATTCAGCCCACTGCCC AATGCCTGCTTCCTGGGCATAGCCATGGAACCCTGCCAGGCTGCT AAAGGACAGTGGATGCTGCTGGGCCTCTGCCTTGTCCTGATGCTG TGCTCAATCAGCCTGGCCATCTGGATTTTCACACAGTAAAGCAGG AAGCCTCCAAGGTAACCCGGCTATGGGACTGCAGTGCCCAAGGAA TTTCTGCTCTGGTTAGAAAAAGGACTCTGCTTCAGTCCACTTCTG CTCTGGTTAGAAAAAGGACTCTGCTTCAGTCCACAGTACATAAAA TGTACTCAGCTATCAGCTCTATAAGAGCTGGATGCACATCAGGAG TGTGCCCCTCTGTAACAACTCTAGTCAGCACAGGCCATGGTGCAC AAAAGGGACTTGGAAAATGATGGAATGACCAGCCTGTCCAACAGA GGGGCAGCCAGGACATCTCTGCCCTCTTCTCATCCCCCAGCCACA GTGGCCAAAGAGGCCCCCACTAGGCACTGTGGCTCTGCATGACAA ACACACATCCAGCCCAGGACTCTAAGCCTCTCACCTGGACTCCAG TAAAAACCTTGCTGAGCCTCCTTGTCTATCCTTCCTCCCCCACCC ACCATTGTAAAGTTTATGTCACCAGAATATTTCTTTCATGTCTAA TTGCTTAAGAACTTGGTTGTTCATCAATTAAATCTAGATGTCCAG AAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 17 | |||||||||||
| Location | 17q23.3 | ||||||||||||
| Strand |
|
||||||||||||
| Database links | RefSeq | NM_152830 | |||||||||||
| KEGG Genes | 1636 | ||||||||||||
| GeneCard | ACE |
| sequence | sequence of CDS | ATGGGCCAGGGTTGGGCTACTGCAGGACTTCCCAGCCTCCTCTTCCTGCTGCTCTGCTACGGGCACCCTCTGCTGGTCCCCAGCCAGGAGGCATCCCAACAGGTGACAGTCACCCATGGGACAAGCAGCCAGGCAACAACCAGCAGCCAGACAACCACCCACCAGGCGACGGCCCACCAGACATCAGCCCAGAGCCCAAACCTGGTGACTGATGAGGCTGAGGCCAGCAAGTTTGTGGAGGAATATGACCGGACATCCCAGGTGGTGTGGAACGAGTATGCCGAGGCCAACTGGAACTACAACACCAACATCACCACAGAGACCAGCAAGATTCTGCTGCAGAAGAACATGCAAATAGCCAACCACACCCTGAAGTACGGCACCCAGGCCAGGAAGTTTGATGTGAACCAGTTGCAGAACACCACTATCAAGCGGATCATAAAGAAGGTTCAGGACCTAGAACGGGCAGCACTGCCTGCCCAGGAGCTGGAGGAGTACAACAAGATCCTGTTGGATATGGAAACCACCTACAGCGTGGCCACTGTGTGCCACCCGAATGGCAGCTGCCTGCAGCTCGAGCCAGATCTGACGAATGTGATGGCCACGTCCCGGAAATATGAAGACCTGTTATGGGCATGGGAGGGCTGGCGAGACAAGGCGGGGAGAGCCATCCTCCAGTTTTACCCGAAATACGTGGAACTCATCAACCAGGCTGCCCGGCTCAATGGCTATGTAGATGCAGGGGACTCGTGGAGGTCTATGTACGAGACACCATCCCTGGAGCAAGACCTGGAGCGGCTCTTCCAGGAGCTGCAGCCACTCTACCTCAACCTGCATGCCTACGTGCGCCGGGCCCTGCACCGTCACTACGGGGCCCAGCACATCAACCTGGAGGGGCCCATTCCTGCTCACCTGCTGGGGAACATGTGGGCGCAGACCTGGTCCAACATCTATGACTTGGTGGTGCCCTTCCCTTCAGCCCCCTCGATGGACACCACAGAGGCTATGCTAAAGCAGGGCTGGACGCCCAGGAGGATGTTTAAGGAGGCTGATGATTTCTTCACCTCCCTGGGGCTGCTGCCCGTGCCTCCTGAGTTCTGGAACAAGTCGATGCTGGAGAAGCCAACCGACGGGCGGGAGGTGGTCTGCCACGCCTCGGCCTGGGACTTCTACAACGGCAAGGACTTCCGGATCAAGCAGTGCACCACCGTGAACTTGGAGGACCTGGTGGTGGCCCACCACGAAATGGGCCACATCCAGTATTTCATGCAGTACAAAGACTTACCTGTGGCCTTGAGGGAGGGTGCCAACCCCGGCTTCCATGAGGCCATTGGGGACGTGCTAGCCCTCTCAGTGTCTACGCCCAAGCACCTGCACAGTCTCAACCTGCTGAGCAGTGAGGGTGGCAGCGACGAGCATGACATCAACTTTCTGATGAAGATGGCCCTTGACAAGATCGCCTTTATCCCCTTCAGCTACCTCGTCGATCAGTGGCGCTGGAGGGTATTTGATGGAAGCATCACCAAGGAGAACTATAACCAGGAGTGGTGGAGCCTCAGGCTGAAGTACCAGGGCCTCTGCCCCCCAGTGCCCAGGACTCAAGGTGACTTTGACCCAGGGGCCAAGTTCCACATTCCTTCTAGCGTGCCTTACATCAGGTACTTTGTCAGCTTCATCATCCAGTTCCAGTTCCACGAGGCACTGTGCCAGGCAGCTGGCCACACGGGCCCCCTGCACAAGTGTGACATCTACCAGTCCAAGGAGGCCGGGCAGCGCCTGGCGACCGCCATGAAGCTGGGCTTCAGTAGGCCGTGGCCGGAAGCCATGCAGCTGATCACGGGCCAGCCCAACATGAGCGCCTCGGCCATGTTGAGCTACTTCAAGCCGCTGCTGGACTGGCTCCGCACGGAGAACGAGCTGCATGGGGAGAAGCTGGGCTGGCCGCAGTACAACTGGACGCCGAACTCCGCTCGCTCAGAAGGGCCCCTCCCAGACAGCGGCCGCGTCAGCTTCCTGGGCCTGGACCTGGATGCGCAGCAGGCCCGCGTGGGCCAGTGGCTGCTGCTCTTCCTGGGCATCGCCCTGCTGGTAGCCACCCTGGGCCTCAGCCAGCGGCTCTTCAGCATCCGCCACCGCAGCCTCCACCGGCACTCCCACGGGCCCCAGTTCGGCTCCGAGGTGGAGCTGAGACACTCCTGA |
| sequence of protein | MGQGWATAGLPSLLFLLLCYGHPLLVPSQEASQQVTVTHGTSSQATTSSQTTTHQATAHQTSAQSPNLVTDEAEASKFVEEYDRTSQVVWNEYAEANWNYNTNITTETSKILLQKNMQIANHTLKYGTQARKFDVNQLQNTTIKRIIKKVQDLERAALPAQELEEYNKILLDMETTYSVATVCHPNGSCLQLEPDLTNVMATSRKYEDLLWAWEGWRDKAGRAILQFYPKYVELINQAARLNGYVDAGDSWRSMYETPSLEQDLERLFQELQPLYLNLHAYVRRALHRHYGAQHINLEGPIPAHLLGNMWAQTWSNIYDLVVPFPSAPSMDTTEAMLKQGWTPRRMFKEADDFFTSLGLLPVPPEFWNKSMLEKPTDGREVVCHASAWDFYNGKDFRIKQCTTVNLEDLVVAHHEMGHIQYFMQYKDLPVALREGANPGFHEAIGDVLALSVSTPKHLHSLNLLSSEGGSDEHDINFLMKMALDKIAFIPFSYLVDQWRWRVFDGSITKENYNQEWWSLRLKYQGLCPPVPRTQGDFDPGAKFHIPSSVPYIRYFVSFIIQFQFHEALCQAAGHTGPLHKCDIYQSKEAGQRLATAMKLGFSRPWPEAMQLITGQPNMSASAMLSYFKPLLDWLRTENELHGEKLGWPQYNWTPNSARSEGPLPDSGRVSFLGLDLDAQQARVGQWLLLFLGIALLVATLGLSQRLFSIRHRSLHRHSHGPQFGSEVELRHS | |
| Database link | RefSeq | NM_152830 |
| UniProt | ||
| CCDS |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
|
| Disease | Summary |
| This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [provided by RefSeq, May 2010] |
|
|||||||||||
