Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU002928 |
| Korean Unigene Clone | IRAT-31-D12 | |
| Original Clone | IRAK-47-L24 | |
| Vector | pBluescriptR | |
| Gene | MSH4 | |
| Gene Description | mutS homolog 4 | |
| Clone sequence size | 3283 (bp) | |
| Fullness | F | |
| Mutation | 381,1197,1671,1677 | |
| Amino acid - mutation | GAA(E)-> GAG(E),ATT(I)-> GTT(V),TAT(Y)-> TAC(Y),CTA(L)-> CTT(L) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 3283 |
| Sequence | AGCGGAGTTCTCCCGCCCGTTTCAGCGGCGCAGCTTCTGTAGTTG GGCTACTGGAGGGGTCGCTCAGAAACCTCATACTTCTCGGGTCAG GGAAGGTTTGGGAGGATGCTGAGGCCTGAGATCTCATCAACCTCG CCTTCTGCCCCGGCGGTTTCCCCGTCGTCGGGAGAAACCCGCTCA CCTCAGGGTCCCCGCTACAATTTCGGACTCCAGGAGACTCCACAG AGCCGCCCTTCGGTCCAGGTGGTCTCTGCATCCACCTGTCCTGGC ACGTCAGGAGCTGCGGGCGACCGGAGCAGCAGCAGCAGCAGCCTT CCCTGCCCCGCGCCAAACTCCCGGCCAGCTCAAGGTTCATACTTT GGAAACAAAAGAGCTTATGCAGAGAACACAGTTGCATCAAATTTT ACTTTTGGTGCAAGCTCATCTTCTGCACGAGATACTAATTATCCT CAAACACTTAAAACTCCATTGTCTACTGGAAATCCTCAGAGATCA GGTTATAAGAGCTGGACACCACAAGTGGGATATTCAGCTTCATCC TCATCTGCGATTTCTGCACACTCCCCATCAGTTATTGTAGCTGTT GTAGAAGGGAGAGGACTTGCCAGAGGTGAAATAGGAATGGCAAGT ATTGATTTAAAAAACCCCCAAATTATACTATCCCAGTTTGCAGAC AACACAACATATGCAAAGGTGATCACTAAACTTAAAATTTTATCA CCTTTGGAAATAATAATGTCAAATACTGCTTGTGCTGTGGGGAAT TCCACCAAGTTGTTCACTCTGATCACAGAAAATTTCAAGAATGTT AATTTCACTACTATCCAAAGGAAATACTTCAATGAAACAAAAGGA TTAGAGTACATTGAACAGTTATGCATAGCAGAATTCAGCACTGTC CTAATGGAGGTTCAGTCCAAGTATTACTGCCTTGCAGCTGTTGCA GCTTTGTTAAAATATGTTGAATTTATTCAAAATTCAGTTTATGCA CCAAAATCACTGAAGATTTGTTTCCAGGGTAGTGAACAGACAGCC ATGATAGATTCATCATCAGCCCAAAACCTTGAATTGTTAATTAAT AATCAAGACTATAGGAATAATCACACTCTCTTTGGTGTTCTAAAT TATACTAAGACTCCTGGAGGGAGTAGACGACTTCGTTCTAATATA TTAGAGCCTCTAGTTGATATTGAAACCGTTAACATGAGATTAGAT TGTGTTCAAGAACTACTTCAAGATGAGGAACTATTTTTTGGACTT CAATCAGTTATATCAAGATTTCTTGATACAGAGCAGCTTCTTTCT GTTTTAGTCCAAATTCCAAAGCAAGACACGGTCAATGCTGCTGAA TCAAAGATAACAAATTTAATATACTTAAAACATACCTTGGAACTT GTGGATCCTTTAAAGATTGCTATGAAGAACTGTAACACACCTTTA TTAAGAGCTTACTATGGTTCCTTGGAAGACAAGAGGTTTGGAATC ATACTTGAAAAGATTAAAACAGTAATTAATGATGATGCAAGATAC ATGAAAGGATGCCTAAACATGAGGACTCAGAAGTGCTATGCAGTG AGGTCTAACATAAATGAATTTCTTGACATAGCAAGAAGAACATAC ACAGAGATTGTAGATGACATAGCAGGAATGATATCACAACTTGGA GAAAAATACAGTCTTCCTTTAAGGACAAGTTTTAGCTCTGCTCGA GGATTTTTCATCCAGATGACTACAGATTGTATAGCCCTACCTAGT GATCAACTTCCTTCAGAATTTATTAAGATTTCTAAAGTGAAAAAT TCTTACAGCTTTACATCAGCAGATTTAATTAAAATGAATGAAAGA TGCCAAGAATCTTTGAGAGAAATCTATCACATGACTTATATGATA GTGTGCAAACTGCTTAGTGAGATTTATGAACATATTCATTGCTTA TATAAACTATCTGACACTGTGTCAATGCTGGATATGCTACTGTCA TTTGCTCATGCCTGCACTCTTTCTGACTATGTTCGACCAGAATTT ACTGATACTTTAGCAATCAAACAGGGATGGCATCCTATTCTTGAA AAAATATCTGCGGAAAAACCTATTGCCAACAATACCTATGTTACA GAAGGGAGTAATTTTTTGATCATAACTGGACCAAACATGAGTGGA AAATCCACATATTTAAAACAGATTGCTCTTTGTCAGATTATGGCC CAGATTGGATCATATGTTCCAGCAGAATATTCTTCCTTTAGAATT GCTAAACAGATTTTTACAAGAATTAGTACTGATGATGATATCGAA ACAAATTCATCAACATTTATGAAAGAAATGAAAGAGATAGCATAT ATTCTACATAATGCTAATGACAAATCGCTCATATTAATTGATGAA CTTGGCAGAGGTACTAATACGGAAGAAGGTATTGGCATTTGTTAT GCTGTTTGTGAATATCTACTGAGCTTAAAGGCATTTACACTGTTT GCTACACATTTCCTGGAACTATGCCATATTGATGCCCTGTATCCT AATGTAGAAAACATGCATTTTGAAGTTCAACATGTAAAGAATACC TCAAGAAATAAAGAAGCAATTTTGTATACCTACAAACTTTCTAAG GGACTCACAGAAGAGAAAAATTATGGATTAAAAGCTGCAGAGGTG TCATCACTTCCACCATCAATTGTCTTGGATGCCAAGGAAATCACA ACTCAAATTACGAGACAAATTTTGCAAAACCAAAGGAGTACCCCT GAGATGGAAAGACAGAGAGCTGTGTACCATCTAGCCACTAGGCTT GTTCAAACTGCTCGAAACTCTCAATTGGATCCAGACAGTTTACGA ATATATTTAAGTAACCTCAAGAAGAAGTACAAAGAAGATTTTCCC AGGACTGAACAAGTTCCAGAAAAGACTGAAGAATAATCACAATTC TAATGTAATAATATATCTTAATTCAAGGAACCTAGAATTTATTTT TCTCCTTAGAGATAAGGAAAATAACATTTGCCAAATTTCATATTT TAATTGAAAATTACATTATATTAACATCACAATTGTCATCTATAT ATTCTATATGAAAAATATTTATTATAACTTAACAAATGAGAACTA CTTAAAGGAATGGTTTTTATGTTAGGAGAAAATACAATACACCAC TTTTTTCTCACAAAAATTCACATTATTAAGACCTAAGTTCATTTA TACTTACAAGTTATAGTTTAAAATATTATTGTAAATACCCTAGTT TAATAAACACCTTTCTTTTTAGGTCTGAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 1 | |||||||||||
| Location | 1p31 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_002440 | |||||||||||
| KEGG Genes | 4438 | ||||||||||||
| GeneCard | MSH4 |
| sequence | sequence of CDS | ATGCTGAGGCCTGAGATCTCATCAACCTCGCCTTCTGCCCCGGCGGTTTCCCCGTCGTCGGGAGAAACCCGCTCACCTCAGGGTCCCCGCTACAATTTCGGACTCCAGGAGACTCCACAGAGCCGCCCTTCGGTCCAGGTGGTCTCTGCATCCACCTGTCCTGGCACGTCAGGAGCTGCGGGCGACCGGAGCAGCAGCAGCAGCAGCCTTCCCTGCCCCGCGCCAAACTCCCGGCCAGCTCAAGGTTCATACTTTGGAAACAAAAGAGCTTATGCAGAAAACACAGTTGCATCAAATTTTACTTTTGGTGCAAGCTCATCTTCTGCACGAGATACTAATTATCCTCAAACACTTAAAACTCCATTGTCTACTGGAAATCCTCAGAGATCAGGTTATAAGAGCTGGACACCACAAGTGGGATATTCAGCTTCATCCTCATCTGCGATTTCTGCACACTCCCCATCAGTTATTGTAGCTGTTGTAGAAGGGAGAGGACTTGCCAGAGGTGAAATAGGAATGGCAAGTATTGATTTAAAAAACCCCCAAATTATACTATCCCAGTTTGCAGACAACACAACATATGCAAAGGTGATCACTAAACTTAAAATTTTATCACCTTTGGAAATAATAATGTCAAATACTGCTTGTGCTGTGGGGAATTCCACCAAGTTGTTCACTCTGATCACAGAAAATTTCAAGAATGTTAATTTCACTACTATCCAAAGGAAATACTTCAATGAAACAAAAGGATTAGAGTACATTGAACAGTTATGCATAGCAGAATTCAGCACTGTCCTAATGGAGGTTCAGTCCAAGTATTACTGCCTTGCAGCTGTTGCAGCTTTGTTAAAATATGTTGAATTTATTCAAAATTCAGTTTATGCACCAAAATCACTGAAGATTTGTTTCCAGGGTAGTGAACAGACAGCCATGATAGATTCATCATCAGCCCAAAACCTTGAATTGTTAATTAATAATCAAGACTATAGGAATAATCACACTCTCTTTGGTGTTCTAAATTATACTAAGACTCCTGGAGGGAGTAGACGACTTCGTTCTAATATATTAGAGCCTCTAGTTGATATTGAAACCATTAACATGAGATTAGATTGTGTTCAAGAACTACTTCAAGATGAGGAACTATTTTTTGGACTTCAATCAGTTATATCAAGATTTCTTGATACAGAGCAGCTTCTTTCTGTTTTAGTCCAAATTCCAAAGCAAGACACGGTCAATGCTGCTGAATCAAAGATAACAAATTTAATATACTTAAAACATACCTTGGAACTTGTGGATCCTTTAAAGATTGCTATGAAGAACTGTAACACACCTTTATTAAGAGCTTACTATGGTTCCTTGGAAGACAAGAGGTTTGGAATCATACTTGAAAAGATTAAAACAGTAATTAATGATGATGCAAGATACATGAAAGGATGCCTAAACATGAGGACTCAGAAGTGCTATGCAGTGAGGTCTAACATAAATGAATTTCTTGACATAGCAAGAAGAACATACACAGAGATTGTAGATGACATAGCAGGAATGATATCACAACTTGGAGAAAAATATAGTCTACCTTTAAGGACAAGTTTTAGCTCTGCTCGAGGATTTTTCATCCAGATGACTACAGATTGTATAGCCCTACCTAGTGATCAACTTCCTTCAGAATTTATTAAGATTTCTAAAGTGAAAAATTCTTACAGCTTTACATCAGCAGATTTAATTAAAATGAATGAAAGATGCCAAGAATCTTTGAGAGAAATCTATCACATGACTTATATGATAGTGTGCAAACTGCTTAGTGAGATTTATGAACATATTCATTGCTTATATAAACTATCTGACACTGTGTCAATGCTGGATATGCTACTGTCATTTGCTCATGCCTGCACTCTTTCTGACTATGTTCGACCAGAATTTACTGATACTTTAGCAATCAAACAGGGATGGCATCCTATTCTTGAAAAAATATCTGCGGAAAAACCTATTGCCAACAATACCTATGTTACAGAAGGGAGTAATTTTTTGATCATAACTGGACCAAACATGAGTGGAAAATCCACATATTTAAAACAGATTGCTCTTTGTCAGATTATGGCCCAGATTGGATCATATGTTCCAGCAGAATATTCTTCCTTTAGAATTGCTAAACAGATTTTTACAAGAATTAGTACTGATGATGATATCGAAACAAATTCATCAACATTTATGAAAGAAATGAAAGAGATAGCATATATTCTACATAATGCTAATGACAAATCGCTCATATTAATTGATGAACTTGGCAGAGGTACTAATACGGAAGAAGGTATTGGCATTTGTTATGCTGTTTGTGAATATCTACTGAGCTTAAAGGCATTTACACTGTTTGCTACACATTTCCTGGAACTATGCCATATTGATGCCCTGTATCCTAATGTAGAAAACATGCATTTTGAAGTTCAACATGTAAAGAATACCTCAAGAAATAAAGAAGCAATTTTGTATACCTACAAACTTTCTAAGGGACTCACAGAAGAGAAAAATTATGGATTAAAAGCTGCAGAGGTGTCATCACTTCCACCATCAATTGTCTTGGATGCCAAGGAAATCACAACTCAAATTACGAGACAAATTTTGCAAAACCAAAGGAGTACCCCTGAGATGGAAAGACAGAGAGCTGTGTACCATCTAGCCACTAGGCTTGTTCAAACTGCTCGAAACTCTCAATTGGATCCAGACAGTTTACGAATATATTTAAGTAACCTCAAGAAGAAGTACAAAGAAGATTTTCCCAGGACTGAACAAGTTCCAGAAAAGACTGAAGAATAA |
| sequence of protein | MLRPEISSTSPSAPAVSPSSGETRSPQGPRYNFGLQETPQSRPSVQVVSASTCPGTSGAAGDRSSSSSSLPCPAPNSRPAQGSYFGNKRAYAENTVASNFTFGASSSSARDTNYPQTLKTPLSTGNPQRSGYKSWTPQVGYSASSSSAISAHSPSVIVAVVEGRGLARGEIGMASIDLKNPQIILSQFADNTTYAKVITKLKILSPLEIIMSNTACAVGNSTKLFTLITENFKNVNFTTIQRKYFNETKGLEYIEQLCIAEFSTVLMEVQSKYYCLAAVAALLKYVEFIQNSVYAPKSLKICFQGSEQTAMIDSSSAQNLELLINNQDYRNNHTLFGVLNYTKTPGGSRRLRSNILEPLVDIETINMRLDCVQELLQDEELFFGLQSVISRFLDTEQLLSVLVQIPKQDTVNAAESKITNLIYLKHTLELVDPLKIAMKNCNTPLLRAYYGSLEDKRFGIILEKIKTVINDDARYMKGCLNMRTQKCYAVRSNINEFLDIARRTYTEIVDDIAGMISQLGEKYSLPLRTSFSSARGFFIQMTTDCIALPSDQLPSEFIKISKVKNSYSFTSADLIKMNERCQESLREIYHMTYMIVCKLLSEIYEHIHCLYKLSDTVSMLDMLLSFAHACTLSDYVRPEFTDTLAIKQGWHPILEKISAEKPIANNTYVTEGSNFLIITGPNMSGKSTYLKQIALCQIMAQIGSYVPAEYSSFRIAKQIFTRISTDDDIETNSSTFMKEMKEIAYILHNANDKSLILIDELGRGTNTEEGIGICYAVCEYLLSLKAFTLFATHFLELCHIDALYPNVENMHFEVQHVKNTSRNKEAILYTYKLSKGLTEEKNYGLKAAEVSSLPPSIVLDAKEITTQITRQILQNQRSTPEMERQRAVYHLATRLVQTARNSQLDPDSLRIYLSNLKKKYKEDFPRTEQVPEKTEE | |
| Database link | RefSeq | NM_002440 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. [provided by RefSeq, Aug 2011] |
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