Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU003362 |
| Korean Unigene Clone | IRAT-37-A02 | |
| Original Clone | IRAK-12-O19 | |
| Vector | pCMV-SPORT6 | |
| Gene | NOD1 | |
| Gene Description | nucleotide binding oligomerization domain containing 1 | |
| Clone sequence size | 4422 (bp) | |
| Fullness | F | |
| Mutation | 1419,1869 | |
| Amino acid - mutation | CGC(R)-> CGT(R),CGC(R)-> CAC(H) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 4422 |
| Sequence | CCCGGCCCCGGCGTCCCCGGACCATGGCGCTCTCCGGGCTCTTCT CTAGCTCTCAGCGGCTGCGAAGTCTGTAAACCTGGTGGCCAAGTG ATTGTAAGTCAGGAGACTTTCCTTCGGTTTCTGCCTTTGATGGCA AGAGGTGGAGATTGTGGCGGCGATTACAGAAAACGTCTGGGAAGA CAAGTTGCTGTTTTTATGGGAATCGCAGGCTTGGAAGAGACAGAA GCAATTCCAGAAATAAATTGGAAATTGAAGATTTAAACAATGTTG TTTTAAAACATTCTAACTTCAAAGAATGATGCCAGAAACTTAAAA AGGGGCTGCGCAGAGTAGCAGGGGCCCTGGAGGGCGCGGCCTGAA TCCTGATTGCCCTTCTGCTGAGAGGACACACGCAGCTGAAGATGA ATTTGGGAAAAGTAGCCGCTTGCTACTTTAACTATGGAAGAGCAG GGCCACAGTGAGATGGAAATAATCCCATCAGAGTCTCACCCCCAC ATTCAATTACTGAAAAGCAATCGGGAACTTCTGGTCACTCACATC CGCAATACTCAGTGTCTGGTGGACAACTTGCTGAAGAATGACTAC TTCTCGGCCGAAGATGCGGAGATTGTGTGTGCCTGCCCCACCCAG CCTGACAAGGTCCGCAAAATTCTGGACCTGGTACAGAGCAAGGGC GAGGAGGTGTCCGAGTTCTTCCTCTACTTGCTCCAGCAACTCGCA GATGCCTACGTGGACCTCAGGCCTTGGCTGCTGGAGATCGGCTTC TCCCCTTCCCTGCTCACTCAGAGCAAAGTCGTGGTCAACACTGAC CCAGTGAGCAGGTATACCCAGCAGCTGCGACACCATCTGGGCCGT GACTCCAAGTTCGTGCTGTGCTATGCCCAGAAGGAGGAGCTGCTG CTGGAGGAGATCTACATGGACACCATCATGGAGCTGGTTGGCTTC AGCAATGAGAGCCTGGGCAGCCTGAACAGCCTGGCCTGCCTCCTG GACCACACCACCGGCATCCTCAATGAGCAGGGTGAGACCATCTTC ATCCTGGGTGATGCTGGGGTGGGCAAGTCCATGCTGCTACAGCGG CTGCAGAGCCTCTGGGCCACGGGCCGGCTAGACGCAGGGGTCAAA TTCTTCTTCCACTTTCGCTGCCGCATGTTCAGCTGCTTCAAGGAA AGTGACAGGCTGTGTCTGCAGGACCTGCTCTTCAAGCACTACTGC TACCCAGAGCGGGACCCCGAGGAGGTGTTTGCCTTCCTGCTGCGC TTCCCCCACGTGGCCCTCTTCACCTTCGATGGCCTGGACGAGCTG CACTCGGACTTGGACCTGAGCCGTGTGCCTGACAGCTCCTGCCCC TGGGAGCCTGCCCACCCCCTGGTCTTGCTGGCCAACCTGCTCAGT GGGAAGCTGCTCAAGGGGGCTAGCAAGCTGCTCACAGCCCGCACA GGCATCGAGGTCCCGCGCCAGTTCCTGCGGAAGAAGGTGCTTCTC CGGGGCTTCTCCCCCAGCCACCTGCGCGCCTATGCCAGGAGGATG TTCCCCGAGCGGGCCCTGCAGGACCGCCTGCTGAGCCAGCTGGAG GCCAACCCCAACCTCTGCAGCCTGTGCTCTGTGCCCCTCTTCTGC TGGATCATCTTCCGGTGCTTCCAGCACTTCCGTGCTGCCTTTGAA GGCTCACCACAGCTGCCCGACTGCACGATGACCCTGACAGATGTC TTCCTCCTGGTCACTGAGGTCCATCTGAACAGGATGCAGCCCAGC AGCCTGGTGCAGCGGAACACACACAGCCCAGTGGAGACCCTCCAC GCCGGCCGGGACACTCTGTGCTCGCTGGGGCAGGTGGCCCACCGG GGCATGGAGAAGAGCCTCTTTGTCTTCACCCAGGAGGAGGTGCAG GCCTCCGGGCTGCAGGAGAGAGACATGCAGCTGGGCTTCCTGCGG GCTTTGCCGGAGCTGGGCCCCGGGGGTGACCAGCAGTCCTATGAG TTTTTCCACCTCACCCTCCAGGCCTTCTTTACAGCCTTCTTCCTC GTGCTGGACGACAGGGTGGGCACTCAGGAGCTGCTCAGGTTCTTC CAGGAGTGGATGCCCCCTGCGGGGGCAGCGACCACGTCCTGCTAT CCTCCCTTCCTCCCGTTCCAGTGCCTGCAGGGCAGTGGTCCGGCG CGGGAAGACCTCTTCAAGAACAAGGATCACTTCCAGTTCACCAAC CTCTTCCTGTGCGGGCTGTTGTCCAAAGCCAAACAGAAACTCCTG CGGCATCTGGTGCCCGCGGCAGCCCTGAGGAGAAAGCGCAAGGCC CTGTGGGCACACCTGTTTTCCAGCCTGCGGGGCTACCTGAAGAGC CTGCCCCGCGTTCAGGTCGAAAGCTTCAACCAGGTGCAGGCCATG CCCACGTTCATCTGGATGCTGCGCTGCATCTACGAGACACAGAGC CAGAAGGTGGGGCAGCTGGCGGCCAGGGGCATCTGCGCCAACTAC CTCAAGCTGACCTACTGCAACGCCTGCTCGGCCGACTGCAGCGCC CTCTCCTTCGTCCTGCATCACTTCCCCAAGCGGCTGGCCCTAGAC CTAGACAACAACAATCTCAACGACTACGGCGTGCGGGAGCTGCAG CCCTGCTTCAGCCGCCTCACTGTTCTCAGACTCAGCGTAAACCAG ATCACTGACGGTGGGGTAAAGGTGCTAAGCGAAGAGCTGACCAAA TACAAAATTGTGACCTATTTGGGTTTATACAACAACCAGATCACC GATGTCGGAGCCAGGTACGTCACCAAAATCCTGGATGAATGCAAA GGCCTCACGCATCTTAAACTGGGAAAAAACAAAATAACAAGTGAA GGAGGGAAGTATCTCGCCCTGGCTGTGAAGAACAGCAAATCAATC TCTGAGGTTGGGATGTGGGGCAATCAAGTTGGGGATGAAGGAGCA AAAGCCTTCGCAGAGGCTCTGCGGAACCACCCCAGCTTGACCACC CTGAGTCTTGCGTCCAACGGCATCTCCACAGAAGGAGGAAAGAGC CTTGCGAGGGCCCTGCAGCAGAACACGTCTCTAGAAATACTGTGG CTGACCCAAAATGAACTCAACGATGAAGTGGCAGAGAGTTTGGCA GAAATGTTGAAAGTCAACCAGACGTTAAAGCATTTATGGCTTATC CAGAATCAGATCACAGCTAAGGGGACTGCCCAGCTGGCAGATGCG TTACAGAGCAACACTGGCATAACAGAGATTTGCCTAAATGGAAAC CTGATAAAACCAGAGGAGGCCAAAGTCTATGAAGATGAGAAGCGG ATTATCTGTTTCTGAGAGGATGCTTTCCTGTTCATGGGGTTTTTG CCCTGGAGCCTCAGCAGCAAATGCCACTCTGGGCAGTCTTTTGTG TCAGTGTCTTAAAGGGGCCTGCGCAGGCGGGACTATCAGGAGTCC ACTGCCTCCATGATGCAAGCCAGCTTCCTGTGCAGAAGGTCTGGT CGGCAAACTCCCTAAGTACCCGCTACAATTCTGCAGAAAAAGAAT GTGTCTTGCGAGCTGTTGTAGTTACAGTAAATACACTGTGAAGAG ACTTTATTGCCTATTATAATTATTTTTATCTGAAGCTAGAGGAAT AAAGCTGTGAGCAAACAGAGGAGGCCAGCCTCACCTCATTCCAAC ACCTGCCATAGGGACCAACGGGAGCGAGTTGGTCACCGCTCTTTT CATTGAAGAGTTGAGGATGTGGCACAAAGTTGGTGCCAAGCTTCT TGAATAAAACGTGTTTGATGGATTAGTATTATACCTGAAATATTT TCTTCCTTCTCAGCACTTTCCCATGTATTGATACTGGTCCCACTT CACAGCTGGAGACACCGGAGTATGTGCAGTGTGGGATTTGACTCC TCCAAGGTTTTGTGGAAAGTTAATGTCAAGGAAAGGATGCACCAC GGGCTTTTAATTTTAATCCTGGAGTCTCACTGTCTGCTGGCAAAG ATAGAGAATGCCCTCAGCTCTTAGCTGGTCTAAGAATGACGATGC CTTCAAAATGCTGCTTCCACTCAGGGCTTCTCCTCTGCTAGGCTA CCCTCCTCTAGAAGGCTGAGTACCATGGGCTACAGTGTCTGGCCT TGGGAAGAAGTGATTCTGTCCCTCCAAAGAAATAGGGCATGGCTT GCCCCTGTGGCCCTGGCATCCAAATGGCTGCTTTTGTCTCCCTTA CCTCGTGAAGAGGGGAAGTCTCTTCCTGCCTCCCAAGCAGCTGAA GGGTGACTAAACGGGCGCCAAGACTCAGGGGATCGGCTGGGAACT GGGCCAGCAGAGCATGTTGGACACCCCCCACCATGGTGGGCTTGT GGTGGCTGCTCCATGAGGGTGGGGGTGATACTACTAGATCACTTG TCCTCTTGCCAGCTCATTTGTTAATAAAATACTGAAAACACTAAA AAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 7 | |||||||||||
| Location | 7p14.3 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_006092 | |||||||||||
| KEGG Genes | 10392 | ||||||||||||
| GeneCard | NOD1 |
| sequence | sequence of CDS | ATGGAAGAGCAGGGCCACAGTGAGATGGAAATAATCCCATCAGAGTCTCACCCCCACATTCAATTACTGAAAAGCAATCGGGAACTTCTGGTCACTCACATCCGCAATACTCAGTGTCTGGTGGACAACTTGCTGAAGAATGACTACTTCTCGGCCGAAGATGCGGAGATTGTGTGTGCCTGCCCCACCCAGCCTGACAAGGTCCGCAAAATTCTGGACCTGGTACAGAGCAAGGGCGAGGAGGTGTCCGAGTTCTTCCTCTACTTGCTCCAGCAACTCGCAGATGCCTACGTGGACCTCAGGCCTTGGCTGCTGGAGATCGGCTTCTCCCCTTCCCTGCTCACTCAGAGCAAAGTCGTGGTCAACACTGACCCAGTGAGCAGGTATACCCAGCAGCTGCGACACCATCTGGGCCGTGACTCCAAGTTCGTGCTGTGCTATGCCCAGAAGGAGGAGCTGCTGCTGGAGGAGATCTACATGGACACCATCATGGAGCTGGTTGGCTTCAGCAATGAGAGCCTGGGCAGCCTGAACAGCCTGGCCTGCCTCCTGGACCACACCACCGGCATCCTCAATGAGCAGGGTGAGACCATCTTCATCCTGGGTGATGCTGGGGTGGGCAAGTCCATGCTGCTACAGCGGCTGCAGAGCCTCTGGGCCACGGGCCGGCTAGACGCAGGGGTCAAATTCTTCTTCCACTTTCGCTGCCGCATGTTCAGCTGCTTCAAGGAAAGTGACAGGCTGTGTCTGCAGGACCTGCTCTTCAAGCACTACTGCTACCCAGAGCGGGACCCCGAGGAGGTGTTTGCCTTCCTGCTGCGCTTCCCCCACGTGGCCCTCTTCACCTTCGATGGCCTGGACGAGCTGCACTCGGACTTGGACCTGAGCCGCGTGCCTGACAGCTCCTGCCCCTGGGAGCCTGCCCACCCCCTGGTCTTGCTGGCCAACCTGCTCAGTGGGAAGCTGCTCAAGGGGGCTAGCAAGCTGCTCACAGCCCGCACAGGCATCGAGGTCCCGCGCCAGTTCCTGCGGAAGAAGGTGCTTCTCCGGGGCTTCTCCCCCAGCCACCTGCGCGCCTATGCCAGGAGGATGTTCCCCGAGCGGGCCCTGCAGGACCGCCTGCTGAGCCAGCTGGAGGCCAACCCCAACCTCTGCAGCCTGTGCTCTGTGCCCCTCTTCTGCTGGATCATCTTCCGGTGCTTCCAGCACTTCCGTGCTGCCTTTGAAGGCTCACCACAGCTGCCCGACTGCACGATGACCCTGACAGATGTCTTCCTCCTGGTCACTGAGGTCCATCTGAACAGGATGCAGCCCAGCAGCCTGGTGCAGCGGAACACACGCAGCCCAGTGGAGACCCTCCACGCCGGCCGGGACACTCTGTGCTCGCTGGGGCAGGTGGCCCACCGGGGCATGGAGAAGAGCCTCTTTGTCTTCACCCAGGAGGAGGTGCAGGCCTCCGGGCTGCAGGAGAGAGACATGCAGCTGGGCTTCCTGCGGGCTTTGCCGGAGCTGGGCCCCGGGGGTGACCAGCAGTCCTATGAGTTTTTCCACCTCACCCTCCAGGCCTTCTTTACAGCCTTCTTCCTCGTGCTGGACGACAGGGTGGGCACTCAGGAGCTGCTCAGGTTCTTCCAGGAGTGGATGCCCCCTGCGGGGGCAGCGACCACGTCCTGCTATCCTCCCTTCCTCCCGTTCCAGTGCCTGCAGGGCAGTGGTCCGGCGCGGGAAGACCTCTTCAAGAACAAGGATCACTTCCAGTTCACCAACCTCTTCCTGTGCGGGCTGTTGTCCAAAGCCAAACAGAAACTCCTGCGGCATCTGGTGCCCGCGGCAGCCCTGAGGAGAAAGCGCAAGGCCCTGTGGGCACACCTGTTTTCCAGCCTGCGGGGCTACCTGAAGAGCCTGCCCCGCGTTCAGGTCGAAAGCTTCAACCAGGTGCAGGCCATGCCCACGTTCATCTGGATGCTGCGCTGCATCTACGAGACACAGAGCCAGAAGGTGGGGCAGCTGGCGGCCAGGGGCATCTGCGCCAACTACCTCAAGCTGACCTACTGCAACGCCTGCTCGGCCGACTGCAGCGCCCTCTCCTTCGTCCTGCATCACTTCCCCAAGCGGCTGGCCCTAGACCTAGACAACAACAATCTCAACGACTACGGCGTGCGGGAGCTGCAGCCCTGCTTCAGCCGCCTCACTGTTCTCAGACTCAGCGTAAACCAGATCACTGACGGTGGGGTAAAGGTGCTAAGCGAAGAGCTGACCAAATACAAAATTGTGACCTATTTGGGTTTATACAACAACCAGATCACCGATGTCGGAGCCAGGTACGTCACCAAAATCCTGGATGAATGCAAAGGCCTCACGCATCTTAAACTGGGAAAAAACAAAATAACAAGTGAAGGAGGGAAGTATCTCGCCCTGGCTGTGAAGAACAGCAAATCAATCTCTGAGGTTGGGATGTGGGGCAATCAAGTTGGGGATGAAGGAGCAAAAGCCTTCGCAGAGGCTCTGCGGAACCACCCCAGCTTGACCACCCTGAGTCTTGCGTCCAACGGCATCTCCACAGAAGGAGGAAAGAGCCTTGCGAGGGCCCTGCAGCAGAACACGTCTCTAGAAATACTGTGGCTGACCCAAAATGAACTCAACGATGAAGTGGCAGAGAGTTTGGCAGAAATGTTGAAAGTCAACCAGACGTTAAAGCATTTATGGCTTATCCAGAATCAGATCACAGCTAAGGGGACTGCCCAGCTGGCAGATGCGTTACAGAGCAACACTGGCATAACAGAGATTTGCCTAAATGGAAACCTGATAAAACCAGAGGAGGCCAAAGTCTATGAAGATGAGAAGCGGATTATCTGTTTCTGA |
| sequence of protein | MEEQGHSEMEIIPSESHPHIQLLKSNRELLVTHIRNTQCLVDNLLKNDYFSAEDAEIVCACPTQPDKVRKILDLVQSKGEEVSEFFLYLLQQLADAYVDLRPWLLEIGFSPSLLTQSKVVVNTDPVSRYTQQLRHHLGRDSKFVLCYAQKEELLLEEIYMDTIMELVGFSNESLGSLNSLACLLDHTTGILNEQGETIFILGDAGVGKSMLLQRLQSLWATGRLDAGVKFFFHFRCRMFSCFKESDRLCLQDLLFKHYCYPERDPEEVFAFLLRFPHVALFTFDGLDELHSDLDLSRVPDSSCPWEPAHPLVLLANLLSGKLLKGASKLLTARTGIEVPRQFLRKKVLLRGFSPSHLRAYARRMFPERALQDRLLSQLEANPNLCSLCSVPLFCWIIFRCFQHFRAAFEGSPQLPDCTMTLTDVFLLVTEVHLNRMQPSSLVQRNTRSPVETLHAGRDTLCSLGQVAHRGMEKSLFVFTQEEVQASGLQERDMQLGFLRALPELGPGGDQQSYEFFHLTLQAFFTAFFLVLDDRVGTQELLRFFQEWMPPAGAATTSCYPPFLPFQCLQGSGPAREDLFKNKDHFQFTNLFLCGLLSKAKQKLLRHLVPAAALRRKRKALWAHLFSSLRGYLKSLPRVQVESFNQVQAMPTFIWMLRCIYETQSQKVGQLAARGICANYLKLTYCNACSADCSALSFVLHHFPKRLALDLDNNNLNDYGVRELQPCFSRLTVLRLSVNQITDGGVKVLSEELTKYKIVTYLGLYNNQITDVGARYVTKILDECKGLTHLKLGKNKITSEGGKYLALAVKNSKSISEVGMWGNQVGDEGAKAFAEALRNHPSLTTLSLASNGISTEGGKSLARALQQNTSLEILWLTQNELNDEVAESLAEMLKVNQTLKHLWLIQNQITAKGTAQLADALQSNTGITEICLNGNLIKPEEAKVYEDEKRIICF | |
| Database link | RefSeq | NM_006092 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is involved in apoptotic signaling, LRRs participate in protein-protein interactions, and mutations in the NBD may affect the process of oligomerization and subsequent function of the LRR domain. This protein is an intracellular pattern-recognition receptor (PRR) that initiates inflammation in response to a subset of bacteria through the detection of bacterial diaminopimelic acid. Multiple alternatively spliced transcript variants differring in the 5' UTR have been described, but the full-length nature of these variants has not been determined. [provided by RefSeq, Oct 2009] |
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