Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU003383 |
| Korean Unigene Clone | IRAT-37-B11 | |
| Original Clone | IRAK-12-D10 | |
| Vector | pCMV-SPORT6 | |
| Gene | IGF1R | |
| Gene Description | insulin like growth factor 1 receptor | |
| Clone sequence size | 3270 (bp) | |
| Fullness | P | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \33,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 3270 |
| Sequence | GTTTTGTTTAAACTGTCCGAGTTACTGATGTCATTTTGTTTTTGT TTTATGTAGGTAGCTTTTAAGTAGAAAACACTAACAGTGTAGTGC CCATCATAGCAAATGCTTCAGAAACACCTCAATAAAAGAGAAAAC TTGGCTTGTGTGATGGTGCAGTCATTTTACTGGACCAACCCACCC ACCTTGACTATACCAAGGCATCATCTATCCACAGTTCTAGCCTAA CTTCATGCTGATTTCTCTGCCTCTTGATTTTTCTCTGTGTGTTCC AAATAATCTTAAGCTGAGTTGTGGCATTTTCCATGCAACCTCCTT CTGCCAGCAGCTCACACTGCTTGAAGTCATATGAACCACTGAGGC ACATCATGGAATTGATGTGAGCATTAAGACGTTCTCCCACACAGC CCTTCCCTGAGGCAGCAGGAGCTGGTGTGTACTGGAGACACTGTT GAACTTGATCAAGACCCAGACCACCCCAGGTCTCCTTCGTGGGAT GTCATGACGTTTGACATACCTTTGGAACGAGCCTCCTCCTTGGAA GATGGAAGACCGTGTTCGTGGCCGACCTGGCCTCTCCTGGCCTGT TTCTTAAGATGCGGAGTCACATTTCAATGGTACGAAAAGTGGCTT CGTAAAATAGAAGAGCAGTCACTGTGGAACTACCAAATGGCGAGA TGCTCGGTGCACATTGGGGTGCTTTGGGATAAAAGATTTATGAGC CAACTATTCTCTGGCACCAGATTCTAGGCCAGTTTGTTCCACTGA AGCTTTTCCCACAGCAGTCCACCTCTGCAGGCTGGCAGCCGAATG GCTTGCCAGTGGCTCTGTGGCAAGATCACACTGAGATCGATGGGT GAGAAGGCTAGGATGCTTGTCTAGTGTTCTTAGCTGTCACGTTGG CTCCTTCCAGGGTGGCCAGACGGTGTTGGCCACTCCCTTCTAAAA CACAGGCGCCCTCCTGGTGACAGTGACCCGCCGTGGTATGCCTTG GCCCATTCCAGCAGTCCCAGTTATGCATTTCAAGTTTGGGGTTTG TTCTTTTCGTTAATGTTCCTCTGTGTTGTCAGCTGTCTTCATTTC CTGGGCTAAGCAGCATTGGGAGATGTGGACCAGAGATCCACTCCT TAAGAACCAGTGGCGAAAGACACTTTCTTTCTTCACTCTGAAGTA GCTGGTGGTACAAATGAGAACTTCAAGAGAGGATGTTATTTAGAC TGAACCTCTGTTGCCAGAGATGCTGAAGATACAGACCTTGGACAG GTCAGAGGGTTTCATTTTTGGCCTTCATCTTAGATGACTGGTTGC GTCATTTGGAGAAGTGAGTGCTCCTTGATGGTGGAATGACCGGGT GGTGGGTACAGAACCATTGTCACAGGGATCCTGGCACAGAGAAGA GTTACGAGCAGCAGGGTGCAGGGCTTGGAAGGAATGTGGGCAAGG TTTTGAACTTGATTGTTCTTGAAGCTATCAGACCACATCGAGGCT CAGCAGTCATCCGTGGGCATTTGGTTTCAACAAAGAAACCTAACA TCCTACTCTGGAAACTGATCTCGGAGTTAAGGCGAATTGTTCAAG AACACAAACTACATCGCACTCGTCAGTTGTCAGTTCTGGGGCATG ACTTTAGCGTTTTGTTTCTGCGAGAACATAACGATCACTCATTTT TATGTCCCACGTGTGTGTGTCCGCATCTTTCTGGTCAACATTGTT TTAACTAGTCACTCATTAGCGTTTTCAATAGGGCTCTTAAGTCCA GTAGATTACGGGTAGTCAGTTGACGAAGATCTGGTTTACAAGAAC TAATTAAATGTTTCATTGCATTTTTGTAAGAACAGAATAATTTTA TAAAATGTTTGTAGTTTATAATTGCCGAAAATAATTTAAAGACAC TTTTTTTTTCTCTGTGTGTGCAAATGTGTGTTTGTGATCCATTTT TTTTTTTTTTTTAGGACACCTGTTTACTAGCTAGCTTTACAATAT GCCAAAAAAGGATTTCTCCCTGACCCCATCCGTGGTTCACCCTCT TTTCCCCCCATGCTTTTTGCCCTAGTTTATAACAAAGGAATGATG ATGATTTAAAAAGTAGTTCTGTATCTTCAGTATCTTGGTCTTCCA GAACCCTCTGGTTGGGAAGGGGATCATTTTTTACTGGTCATTTCC CTTTGGAGTGTAGCTACTTTAACAGATGGAAAGAACCTCATTGGC CATGGAAACAGCCGAGGTGTTGGAGCCCAGCAGTGCATGGCACCG TTCGGCATCTGGCTTGATTGGTCTGGCTGCCGTCATTGTCAGCAC AGTGCCATGGACATGGGAAGACTTGACTGCACAGCCAATGGTTTT CATGATGATTACAGCATACACAGTGATCACATAAACGATGACAGC TATGGGGCACACAGGCCATTTGCTTACATGCCTCGTATCATGATT GATTACTGCTTTGTTAGAACACAGAAGAGACCCTATTTTATTTAA GGCAGAACCCCGAAGATACGTATTTCCAATACAGAAAAGAATTTT TAATAAAAACTATAACATACACAAAAATTGGTTTTAAAGTTGACT CCACTTCCTCTAACTCCAGTGGATTGTTGGCCATGTCTCCCCAAC TCCACAATATCTCTATCATGGGAAACACCTGGGGTTTTTGCGCTA CATAGGAGAAAGATCTGGAAACTATTTGGGTTTTGTTTTCAACTT TTCATTTGGATGTTTGGCGTTGCACACACACATCCACCGGTGGAA GAGACGCCCGGTGAAAACACCTGTCTGCTTTCTAAGCCAGTGAGG TTGAGGTGAGAGGTTTGCCAGAGTTTGTCTACCTCTGGGTATCCC TTTGTCTGGGATAAAAAAAATCAAACCAGAAGGCGGGATGGAATG GATGCACCGCAAATAATGCATTTTCTGAGTTTTCTTGTTAAAAAA AAATTTTTTTTAAGTAAGAAAAAAAAAGGTAATAACATGGCCAAT TTGTTACATAAAATGACTTTCTGTGTATAAATTATTCCTAAAAAA TCCTGTTTATATAAAAAATCAGTAGATGAAAAAAATTTCAAAATG TTTTTGTATATTCTGTTGTAAGAATTTATTCCTGTTATTGCGATA TACTCTGGATTCTTTACATAATGGAAAAAAGAAACTGTCTATTTT GAATGGCTGAAGCTAAGGCAACGTTAGTTTCTCTTACTCTGCTTT TTTCTAGTAAAGTACTACATGGTTTAAGTTAAATAAAATAATTCT GTATGCAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 15 | |||||||||||
| Location | 15q26.3 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_001291858 | |||||||||||
| KEGG Genes | 3480 | ||||||||||||
| GeneCard | IGF1R |
| sequence | sequence of CDS | ATGAAGTCTGGCTCCGGAGGAGGGTCCCCGACCTCGCTGTGGGGGCTCCTGTTTCTCTCCGCCGCGCTCTCGCTCTGGCCGACGAGTGGAGAAATCTGCGGGCCAGGCATCGACATCCGCAACGACTATCAGCAGCTGAAGCGCCTGGAGAACTGCACGGTGATCGAGGGCTACCTCCACATCCTGCTCATCTCCAAGGCCGAGGACTACCGCAGCTACCGCTTCCCCAAGCTCACGGTCATTACCGAGTACTTGCTGCTGTTCCGAGTGGCTGGCCTCGAGAGCCTCGGAGACCTCTTCCCCAACCTCACGGTCATCCGCGGCTGGAAACTCTTCTACAACTACGCCCTGGTCATCTTCGAGATGACCAATCTCAAGGATATTGGGCTTTACAACCTGAGGAACATTACTCGGGGGGCCATCAGGATTGAGAAAAATGCTGACCTCTGTTACCTCTCCACTGTGGACTGGTCCCTGATCCTGGATGCGGTGTCCAATAACTACATTGTGGGGAATAAGCCCCCAAAGGAATGTGGGGACCTGTGTCCAGGGACCATGGAGGAGAAGCCGATGTGTGAGAAGACCACCATCAACAATGAGTACAACTACCGCTGCTGGACCACAAACCGCTGCCAGAAAATGTGCCCAAGCACGTGTGGGAAGCGGGCGTGCACCGAGAACAATGAGTGCTGCCACCCCGAGTGCCTGGGCAGCTGCAGCGCGCCTGACAACGACACGGCCTGTGTAGCTTGCCGCCACTACTACTATGCCGGTGTCTGTGTGCCTGCCTGCCCGCCCAACACCTACAGGTTTGAGGGCTGGCGCTGTGTGGACCGTGACTTCTGCGCCAACATCCTCAGCGCCGAGAGCAGCGACTCCGAGGGGTTTGTGATCCACGACGGCGAGTGCATGCAGGAGTGCCCCTCGGGCTTCATCCGCAACGGCAGCCAGAGCATGTACTGCATCCCTTGTGAAGGTCCTTGCCCGAAGGTCTGTGAGGAAGAAAAGAAAACAAAGACCATTGATTCTGTTACTTCTGCTCAGATGCTCCAAGGATGCACCATCTTCAAGGGCAATTTGCTCATTAACATCCGACGGGGGAATAACATTGCTTCAGAGCTGGAGAACTTCATGGGGCTCATCGAGGTGGTGACGGGCTACGTGAAGATCCGCCATTCTCATGCCTTGGTCTCCTTGTCCTTCCTAAAAAACCTTCGCCTCATCCTAGGAGAGGAGCAGCTAGAAGGGAATTACTCCTTCTACGTCCTCGACAACCAGAACTTGCAGCAACTGTGGGACTGGGACCACCGCAACCTGACCATCAAAGCAGGGAAAATGTACTTTGCTTTCAATCCCAAATTATGTGTTTCCGAAATTTACCGCATGGAGGAAGTGACGGGGACTAAAGGGCGCCAAAGCAAAGGGGACATAAACACCAGGAACAACGGGGAGAGAGCCTCCTGTGAAAGTGACGTCCTGCATTTCACCTCCACCACCACGTCGAAGAATCGCATCATCATAACCTGGCACCGGTACCGGCCCCCTGACTACAGGGATCTCATCAGCTTCACCGTTTACTACAAGGAAGCACCCTTTAAGAATGTCACAGAGTATGATGGGCAGGATGCCTGCGGCTCCAACAGCTGGAACATGGTGGACGTGGACCTCCCGCCCAACAAGGACGTGGAGCCCGGCATCTTACTACATGGGCTGAAGCCCTGGACTCAGTACGCCGTTTACGTCAAGGCTGTGACCCTCACCATGGTGGAGAACGACCATATCCGTGGGGCCAAGAGTGAGATCTTGTACATTCGCACCAATGCTTCAGTTCCTTCCATTCCCTTGGACGTTCTTTCAGCATCGAACTCCTCTTCTCAGTTAATCGTGAAGTGGAACCCTCCCTCTCTGCCCAACGGCAACCTGAGTTACTACATTGTGCGCTGGCAGCGGCAGCCTCAGGACGGCTACCTTTACCGGCACAATTACTGCTCCAAAGACAAAATCCCCATCAGGAAGTATGCCGACGGCACCATCGACATTGAGGAGGTCACAGAGAACCCCAAGACTGAGGTGTGTGGTGGGGAGAAAGGGCCTTGCTGCGCCTGCCCCAAAACTGAAGCCGAGAAGCAGGCCGAGAAGGAGGAGGCTGAATACCGCAAAGTCTTTGAGAATTTCCTGCACAACTCCATCTTCGTGCCCAGACCTGAAAGGAAGCGGAGAGATGTCATGCAAGTGGCCAACACCACCATGTCCAGCCGAAGCAGGAACACCACGGCCGCAGACACCTACAACATCACCGACCCGGAAGAGCTGGAGACAGAGTACCCTTTCTTTGAGAGCAGAGTGGATAACAAGGAGAGAACTGTCATTTCTAACCTTCGGCCTTTCACATTGTACCGCATCGATATCCACAGCTGCAACCACGAGGCTGAGAAGCTGGGCTGCAGCGCCTCCAACTTCGTCTTTGCAAGGACTATGCCCGCAGAAGGAGCAGATGACATTCCTGGGCCAGTGACCTGGGAGCCAAGGCCTGAAAACTCCATCTTTTTAAAGTGGCCGGAACCTGAGAATCCCAATGGATTGATTCTAATGTATGAAATAAAATACGGATCACAAGTTGAGGATCAGCGAGAATGTGTGTCCAGACAGGAATACAGGAAGTATGGAGGGGCCAAGCTAAACCGGCTAAACCCGGGGAACTACACAGCCCGGATTCAGGCCACATCTCTCTCTGGGAATGGGTCGTGGACAGATCCTGTGTTCTTCTATGTCCAGGCCAAAAGATATGAAAACTTCATCCATCTGATCATCGCTCTGCCCGTCGCTGTCCTGTTGATCGTGGGAGGGTTGGTGATTATGCTGTACGTCTTCCATAGAAAGAGAAATAACAGCAGGCTGGGGAATGGAGTGCTGTATGCCTCTGTGAACCCGGAGTACTTCAGCGCTGCTGATGTGTACGTTCCTGATGAGTGGGAGGTGGCTCGGGAGAAGATCACCATGAGCCGGGAACTTGGGCAGGGGTCGTTTGGGATGGTCTATGAAGGAGTTGCCAAGGGTGTGGTGAAAGATGAACCTGAAACCAGAGTGGCCATTAAAACAGTGAACGAGGCCGCAAGCATGCGTGAGAGGATTGAGTTTCTCAACGAAGCTTCTGTGATGAAGGAGTTCAATTGTCACCATGTGGTGCGATTGCTGGGTGTGGTGTCCCAAGGCCAGCCAACACTGGTCATCATGGAACTGATGACACGGGGCGATCTCAAAAGTTATCTCCGGTCTCTGAGGCCAGAAATGGAGAATAATCCAGTCCTAGCACCTCCAAGCCTGAGCAAGATGATTCAGATGGCCGGAGAGATTGCAGACGGCATGGCATACCTCAACGCCAATAAGTTCGTCCACAGAGACCTTGCTGCCCGGAATTGCATGGTAGCCGAAGATTTCACAGTCAAAATCGGAGATTTTGGTATGACGCGAGATATCTATGAGACAGACTATTACCGGAAAGGAGGGAAAGGGCTGCTGCCCGTGCGCTGGATGTCTCCTGAGTCCCTCAAGGATGGAGTCTTCACCACTTACTCGGACGTCTGGTCCTTCGGGGTCGTCCTCTGGGAGATCGCCACACTGGCCGAGCAGCCCTACCAGGGCTTGTCCAACGAGCAAGTCCTTCGCTTCGTCATGGAGGGCGGCCTTCTGGACAAGCCAGACAACTGTCCTGACATGCTGTTTGAACTGATGCGCATGTGCTGGCAGTATAACCCCAAGATGAGGCCTTCCTTCCTGGAGATCATCAGCAGCATCAAAGAGGAGATGGAGCCTGGCTTCCGGGAGGTCTCCTTCTACTACAGCGAGGAGAACAAGCTGCCCGAGCCGGAGGAGCTGGACCTGGAGCCAGAGAACATGGAGAGCGTCCCCCTGGACCCCTCGGCCTCCTCGTCCTCCCTGCCACTGCCCGACAGACACTCAGGACACAAGGCCGAGAACGGCCCCGGCCCTGGGGTGCTGGTCCTCCGCGCCAGCTTCGACGAGAGACAGCCTTACGCCCACATGAACGGGGGCCGCAAGAACGAGCGGGCCTTGCCGCTGCCCCAGTCTTCGACCTGCTGA |
| sequence of protein | MKSGSGGGSPTSLWGLLFLSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLHILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIFEMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGDLCPGTMEEKPMCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENNECCHPECLGSCSAPDNDTACVACRHYYYAGVCVPACPPNTYRFEGWRCVDRDFCANILSAESSDSEGFVIHDGECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNLLINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRLILGEEQLEGNYSFYVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTRNNGERASCESDVLHFTSTTTSKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDGQDACGSNSWNMVDVDLPPNKDVEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSEILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDGYLYRHNYCSKDKIPIRKYADGTIDIEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKVFENFLHNSIFVPRPERKRRDVMQVANTTMSSRSRNTTAADTYNITDPEELETEYPFFESRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPGNYTARIQATSLSGNGSWTDPVFFYVQAKRYENFIHLIIALPVAVLLIVGGLVIMLYVFHRKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTYSDVWSFGVVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLEIISSIKEEMEPGFREVSFYYSEENKLPEPEELDLEPENMESVPLDPSASSSSLPLPDRHSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC | |
| Database link | RefSeq | NM_001291858 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
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