Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU004066 |
| Korean Unigene Clone | IRAT-44-C10 | |
| Original Clone | IRAK-49-N09 | |
| Vector | pCMV-SPORT6 | |
| Gene | CD4 | |
| Gene Description | CD4 molecule | |
| Clone sequence size | 3084 (bp) | |
| Fullness | F | |
| Mutation | 1223,1541 | |
| Amino acid - mutation | AGT(S)-> AGC(S),TGT(C)-> TGC(C) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 3084 |
| Sequence | CTGGGCTCCTGGTTGCAGAGCTCCAAGTCCTCACACAGATACGCC TGTTTGAGAAGCAGCGGGCAAGAAAGACGCAAGCCCAGAGGCCCT GCCATTTCTGTGGGCTCAGGTCCCTACTGGCTCAGGCCCCTGCCT CCCTCGGCAAGGCCACAATGAACCGGGGAGTCCCTTTTAGGCACT TGCTTCTGGTGCTGCAACTGGCGCTCCTCCCAGCAGCCACTCAGG GAAAGAAAGTGGTGCTGGGCAAAAAAGGGGATACAGTGGAACTGA CCTGTACAGCTTCCCAGAAGAAGAGCATACAATTCCACTGGAAAA ACTCCAACCAGATAAAGATTCTGGGAAATCAGGGCTCCTTCTTAA CTAAAGGTCCATCCAAGCTGAATGATCGCGCTGACTCAAGAAGAA GCCTTTGGGACCAAGGAAACTTTCCCCTGATCATCAAGAATCTTA AGATAGAAGACTCAGATACTTACATCTGTGAAGTGGAGGACCAGA AGGAGGAGGTGCAATTGCTAGTGTTCGGATTGACTGCCAACTCTG ACACCCACCTGCTTCAGGGGCAGAGCCTGACCCTGACCTTGGAGA GCCCCCCTGGTAGTAGCCCCTCAGTGCAATGTAGGAGTCCAAGGG GTAAAAACATACAGGGGGGGAAGACCCTCTCCGTGTCTCAGCTGG AGCTCCAGGATAGTGGCACCTGGACATGCACTGTCTTGCAGAACC AGAAGAAGGTGGAGTTCAAAATAGACATCGTGGTGCTAGCTTTCC AGAAGGCCTCCAGCATAGTCTATAAGAAAGAGGGGGAACAGGTGG AGTTCTCCTTCCCACTCGCCTTTACAGTTGAAAAGCTGACGGGCA GTGGCGAGCTGTGGTGGCAGGCGGAGAGGGCTTCCTCCTCCAAGT CTTGGATCACCTTTGACCTGAAGAACAAGGAAGTGTCTGTAAAAC GGGTTACCCAGGACCCTAAGCTCCAGATGGGCAAGAAGCTCCCGC TCCACCTCACCCTGCCCCAGGCCTTGCCTCAGTATGCTGGCTCTG GAAACCTCACCCTGGCCCTTGAAGCGAAAACAGGAAAGTTGCATC AGGAAGTGAACCTGGTGGTGATGAGAGCCACTCAGCTCCAGAAAA ATTTGACCTGTGAGGTGTGGGGACCCACCTCCCCTAAGCTGATGC TGAGCTTGAAACTGGAGAACAAGGAGGCAAAGGTCTCGAAGCGGG AGAAGGCGGTGTGGGTGCTGAACCCTGAGGCGGGGATGTGGCAGT GTCTGCTGAGTGACTCGGGACAGGTCCTGCTGGAATCCAACATCA AGGTTCTGCCCACATGGTCCACCCCGGTGCAGCCAATGGCCCTGA TTGTGCTGGGGGGCGTCGCCGGCCTCCTGCTTTTCATTGGGCTAG GCATCTTCTTCTGTGTCAGGTGCCGGCACCGAAGGCGCCAAGCAG AGCGGATGTCTCAGATCAAGAGACTCCTCAGTGAGAAGAAGACCT GCCAGTGCCCTCACCGGTTTCAGAAGACATGTAGCCCCATTTGAG GCACGAGGCCAGGCAGATCCCACTTGCAGCCTCCCCAGGTGTCTG CCCCGCGTTTCCTGCCTGCGGACCAGATGAATGTAGCAGATCCCA GGCCTCTGGCCTCCTGTTCGCCTCCTCTACAATTTGCCATTGTTT CTCCTGGGTTAGGCCCCGGCTTCACTGGTTGAGTGTTGCTCTCTA GTTTCCAGAGGCTTAATCACACCGTCCTCCACGCCATTTCCTTTT CCTTCAAGCCTAGCCCTTCTCTCATTATTTCTCTCTGACCCTCTC CCCACTGCTCATTTGGATCCCAGGGGAGTGTTCAGGGCCAGCCCT GGCTGGCATGGAGGGTGAGGCTGGGTGTCTGGAAGCATGGAGCAT GGGACTGTTCTTTTACAAGACAGGACCCTGGGACCACAGAGGGCA GGAGCTTGCACGAAATCACACAGCCAAGCCAGTCAAGGATGGATG CAGATCCAGAGGTTTCTGGCAGCCAGTACCTCCTGCCCCATGCTG CCCGCTTCTCACCCTATGTGGGTGGGGCCACAGACTCACATCCTG ACCTTGCACAAACAGCCCCTCTGGACACAGCCCCATGTACACGGC CTCAAGGGATGTCTCACATCCTCTGTCTATTTGAGACTTAGAAAA ATCCTACAAGGCTGGCAGTGACAGAACTAAGATGATCATCTCCAG TTTATAGACCAGAACCAGAGCTCAGAGAGGCTAGATGATTGATTA CCAAGTGCCGGACTAGCAAGTGCTGGAGTCGGGACTAACCCAGGT CCCTTGTCCCAAGTTCCACTGCTGCCTCTTGAATGCAGGGACAAA TGCCACACGGCTCTCACCAGTGGCTAGTGGTGGGTACTCAATGTG TACTTTTGGGTTCACAGAAGCACAGCACCCATGGGAAGGGTCCAT CTCAGAGAATTTACGAGCAGGGATGAAGGCCTCCCTGTCTAAAAT CCCTCCTTCATCCCCCGCTGGTGGCAGAATCTGTTACCAGAGGAC AAAGCCTTTGGCTCTTCTAATCAGAGTGCAAGCTGGGAGCACAGG CACTGCAGGAGAGAATGCCCAGTGACCAGTCACTGACCCTGTGCA GAACCTCCTGGAAGCGAGCTTTGCTGGGAGAGGGGGTAGCTAGCC TGAGAGGGAACCCTCCAAGGGACCTCAAAGGTGATTGTGCCAGGC TCTGCGCCTGCCCCACACCCTCCCTTACCCTCCTCCAGACCATTC AGGACACAGGGAAATCAGGGTTACAAATCTTCTTGATCCACTTCT CTCAGGATCCCCTCTCTTCCTACCCTTCCTCACCACTTCCCTCAG TCCCAACTCCTTTTCCCTATTTCCTTCTCCTCCTGTCTTTAAAGC CTGCCTCTTCCAGGAAGACCCCCCTATTGCTGCTGGGGCTCCCCA TTTGCTTACTTTGCATTTGTGCCCACTCTCCACCCCTGCTCCCCT GAGCTGAAATAAAAATACAATAAACTTACTATAAAGATAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 12 | |||||||||||
| Location | 12p13.31 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_000616 | |||||||||||
| KEGG Genes | 920 | ||||||||||||
| GeneCard | CD4 |
| sequence | sequence of CDS | ATGAACCGGGGAGTCCCTTTTAGGCACTTGCTTCTGGTGCTGCAACTGGCGCTCCTCCCAGCAGCCACTCAGGGAAAGAAAGTGGTGCTGGGCAAAAAAGGGGATACAGTGGAACTGACCTGTACAGCTTCCCAGAAGAAGAGCATACAATTCCACTGGAAAAACTCCAACCAGATAAAGATTCTGGGAAATCAGGGCTCCTTCTTAACTAAAGGTCCATCCAAGCTGAATGATCGCGCTGACTCAAGAAGAAGCCTTTGGGACCAAGGAAACTTTCCCCTGATCATCAAGAATCTTAAGATAGAAGACTCAGATACTTACATCTGTGAAGTGGAGGACCAGAAGGAGGAGGTGCAATTGCTAGTGTTCGGATTGACTGCCAACTCTGACACCCACCTGCTTCAGGGGCAGAGCCTGACCCTGACCTTGGAGAGCCCCCCTGGTAGTAGCCCCTCAGTGCAATGTAGGAGTCCAAGGGGTAAAAACATACAGGGGGGGAAGACCCTCTCCGTGTCTCAGCTGGAGCTCCAGGATAGTGGCACCTGGACATGCACTGTCTTGCAGAACCAGAAGAAGGTGGAGTTCAAAATAGACATCGTGGTGCTAGCTTTCCAGAAGGCCTCCAGCATAGTCTATAAGAAAGAGGGGGAACAGGTGGAGTTCTCCTTCCCACTCGCCTTTACAGTTGAAAAGCTGACGGGCAGTGGCGAGCTGTGGTGGCAGGCGGAGAGGGCTTCCTCCTCCAAGTCTTGGATCACCTTTGACCTGAAGAACAAGGAAGTGTCTGTAAAACGGGTTACCCAGGACCCTAAGCTCCAGATGGGCAAGAAGCTCCCGCTCCACCTCACCCTGCCCCAGGCCTTGCCTCAGTATGCTGGCTCTGGAAACCTCACCCTGGCCCTTGAAGCGAAAACAGGAAAGTTGCATCAGGAAGTGAACCTGGTGGTGATGAGAGCCACTCAGCTCCAGAAAAATTTGACCTGTGAGGTGTGGGGACCCACCTCCCCTAAGCTGATGCTGAGTTTGAAACTGGAGAACAAGGAGGCAAAGGTCTCGAAGCGGGAGAAGGCGGTGTGGGTGCTGAACCCTGAGGCGGGGATGTGGCAGTGTCTGCTGAGTGACTCGGGACAGGTCCTGCTGGAATCCAACATCAAGGTTCTGCCCACATGGTCCACCCCGGTGCAGCCAATGGCCCTGATTGTGCTGGGGGGCGTCGCCGGCCTCCTGCTTTTCATTGGGCTAGGCATCTTCTTCTGTGTCAGGTGCCGGCACCGAAGGCGCCAAGCAGAGCGGATGTCTCAGATCAAGAGACTCCTCAGTGAGAAGAAGACCTGCCAGTGTCCTCACCGGTTTCAGAAGACATGTAGCCCCATTTGA |
| sequence of protein | MNRGVPFRHLLLVLQLALLPAATQGKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGSFLTKGPSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKEEVQLLVFGLTANSDTHLLQGQSLTLTLESPPGSSPSVQCRSPRGKNIQGGKTLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVVLAFQKASSIVYKKEGEQVEFSFPLAFTVEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRATQLQKNLTCEVWGPTSPKLMLSLKLENKEAKVSKREKAVWVLNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQPMALIVLGGVAGLLLFIGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHRFQKTCSPI | |
| Database link | RefSeq | NM_000616 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, Aug 2010] |
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