Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU004550 |
| Korean Unigene Clone | IRAT-49-D02 | |
| Original Clone | IRAK-62-G21 | |
| Vector | pCMV-SPORT6 | |
| Gene | TNNC1 | |
| Gene Description | troponin C1, slow skeletal and cardiac type | |
| Clone sequence size | 764 (bp) | |
| Fullness | F | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 764 |
| Sequence | GTGAGCCGCCAGCATGGATGACATCTACAAGGCTGCGGTAGAGCA GCTGACAGAAGAGCAGAAAAATGAGTTCAAGGCAGCCTTCGACAT CTTCGTGCTGGGCGCTGAGGATGGCTGCATCAGCACCAAGGAGCT GGGCAAGGTGATGAGGATGCTGGGCCAGAACCCCACCCCTGAGGA GCTGCAGGAGATGATCGATGAGGTGGACGAGGACGGCAGCGGCAC GGTGGACTTTGATGAGTTCCTGGTCATGATGGTTCGGTGCATGAA GGACGACAGCAAAGGGAAATCTGAGGAGGAGCTGTCTGACCTCTT CCGCATGTTTGACAAAAATGCTGATGGCTACATCGACCTGGATGA GCTGAAGATAATGCTGCAGGCTACAGGCGAGACCATCACGGAGGA CGACATCGAGGAGCTCATGAAGGACGGAGACAAGAACAACGACGG CCGCATCGACTATGATGAGTTCCTGGAGTTCATGAAGGGTGTGGA GTAGATGCTGACCTTCACCCAGAGCTGCCTATGCCCAGCCTCCAA CTCCAGCTGAGTCCTGGGGTTGGGGAGGGGGTCGGGGTCCCAGGA CCTGAGCCTGGCCATGTCCTCAACCCCAAATCCCCCGACTCCCTC CCCAGATCTGTCCTGGGGGATGCAAATAAAGCCTGCTCTCCCAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 3 | |||||||||||
| Location | 3p21.1 | ||||||||||||
| Strand |
|
||||||||||||
| Database links | RefSeq | NM_003280 | |||||||||||
| KEGG Genes | 7134 | ||||||||||||
| GeneCard | TNNC1 |
| sequence | sequence of CDS | ATGGATGACATCTACAAGGCTGCGGTAGAGCAGCTGACAGAAGAGCAGAAAAATGAGTTCAAGGCAGCCTTCGACATCTTCGTGCTGGGCGCTGAGGATGGCTGCATCAGCACCAAGGAGCTGGGCAAGGTGATGAGGATGCTGGGCCAGAACCCCACCCCTGAGGAGCTGCAGGAGATGATCGATGAGGTGGACGAGGACGGCAGCGGCACGGTGGACTTTGATGAGTTCCTGGTCATGATGGTTCGGTGCATGAAGGACGACAGCAAAGGGAAATCTGAGGAGGAGCTGTCTGACCTCTTCCGCATGTTTGACAAAAATGCTGATGGCTACATCGACCTGGATGAGCTGAAGATAATGCTGCAGGCTACAGGCGAGACCATCACGGAGGACGACATCGAGGAGCTCATGAAGGACGGAGACAAGAACAACGACGGCCGCATCGACTATGATGAGTTCCTGGAGTTCATGAAGGGTGTGGAGTAG |
| sequence of protein | MDDIYKAAVEQLTEEQKNEFKAAFDIFVLGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRCMKDDSKGKSEEELSDLFRMFDKNADGYIDLDELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGVE | |
| Database link | RefSeq | NM_003280 |
| UniProt | ||
| CCDS |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
|
| Disease | Summary |
| Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008] |
|
|||||||||||
