Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU004762 |
| Korean Unigene Clone | IRAT-51-E10 | |
| Original Clone | IRAK-64-G23 | |
| Vector | pCMV-SPORT6 | |
| Gene | PARP1 | |
| Gene Description | poly(ADP-ribose) polymerase 1 | |
| Clone sequence size | 3677 (bp) | |
| Fullness | F | |
| Mutation | 405,1014,2448 | |
| Amino acid - mutation | GAC(D)-> GAT(D),GCT(A)-> GCC(A),GTG(V)-> GCG(A) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 3677 |
| Sequence | CGGTGGCCGGTGCGGCGTGTTCGGTGGCGGCTCTGGCCGCTCAGG CGCCTGCGGCTGGGTGAGCGCACGCGAGGCGGCGAGGCGGCAGCG TGTTTCTAGGTCGTGGCGTCGGGCTTCCGGAGCTTTGCCGGCAGC TAGGGGAGGATGGCGGAGTCTTCGGATAAGCTCTATCGAGTCGAG TACGCCAAGAGCGGGCGCGCCTCTTGCAAGAAATGCAGCGAGAGC ATCCCCAAGGACTCGCTCCGGATGGCCATCATGGTGCAGTCGCCC ATGTTTGATGGAAAAGTCCCACACTGGTACCACTTCTCCTGCTTC TGGAAGGTGGGCCACTCCATCCGGCACCCTGACGTTGAGGTGGAT GGGTTCTCTGAGCTTCGGTGGGATGATCAGCAGAAAGTCAAGAAG ACAGCGGAAGCTGGAGGAGTGACAGGCAAAGGCCAGGATGGAATT GGTAGCAAGGCAGAGAAGACTCTGGGTGACTTTGCAGCAGAGTAT GCCAAGTCCAACAGAAGTACGTGCAAGGGGTGTATGGAGAAGATA GAAAAGGGCCAGGTGCGCCTGTCCAAGAAGATGGTGGACCCGGAG AAGCCACAGCTAGGCATGATTGACCGCTGGTACCATCCAGGCTGC TTTGTCAAGAACAGGGAGGAGCTGGGTTTCCGGCCCGAGTACAGT GCGAGTCAGCTCAAGGGCTTCAGCCTCCTTGCTACAGAGGATAAA GAAGCCCTGAAGAAGCAGCTCCCAGGAGTCAAGAGTGAAGGAAAG AGAAAAGGCGATGAGGTGGATGGAGTGGATGAAGTGGCGAAGAAG AAATCTAAAAAAGAAAAAGACAAGGATAGTAAGCTTGAAAAAGCC CTAAAGGCTCAGAACGACCTGATCTGGAACATCAAGGACGAGCTA AAGAAAGTGTGTTCAACTAATGACCTGAAGGAGCTACTCATCTTC AACAAGCAGCAAGTGCCTTCTGGGGAGTCGGCGATCTTGGACCGA GTAGCCGATGGCATGGTGTTCGGTGCCCTCCTTCCCTGCGAGGAA TGCTCGGGTCAGCTGGTCTTCAAGAGCGATGCCTATTACTGCACT GGGGACGTCACTGCCTGGACCAAGTGTATGGTCAAGACACAGACA CCCAACCGGAAGGAGTGGGTAACCCCAAAGGAATTCCGAGAAATC TCTTACCTCAAGAAATTGAAGGTTAAAAAACAGGACCGTATATTC CCCCCAGAAACCAGCGCCTCCGTGGCGGCCACGCCTCCGCCCTCC ACAGCCTCGGCTCCTGCTGCTGTGAACTCCTCTGCTTCAGCAGAT AAGCCATTATCCAACATGAAGATCCTGACTCTCGGGAAGCTGTCC CGGAACAAGGATGAAGTGAAGGCCATGATTGAGAAACTCGGGGGG AAGTTGACGGGGACGGCCAACAAGGCTTCCCTGTGCATCAGCACC AAAAAGGAGGTGGAAAAGATGAATAAGAAGATGGAGGAAGTAAAG GAAGCCAACATCCGAGTTGTGTCTGAGGACTTCCTCCAGGACGTC TCCGCCTCCACCAAGAGCCTTCAGGAGTTGTTCTTAGCGCACATC TTGTCCCCTTGGGGGGCAGAGGTGAAGGCAGAGCCTGTTGAAGTT GTGGCCCCAAGAGGGAAGTCAGGGGCTGCGCTCTCCAAAAAAAGC AAGGGCCAGGTCAAGGAGGAAGGTATCAACAAATCTGAAAAGAGA ATGAAATTAACTCTTAAAGGAGGAGCAGCTGTGGATCCTGATTCT GGACTGGAACACTCTGCGCATGTCCTGGAGAAAGGTGGGAAGGTC TTCAGTGCCACCCTTGGCCTGGTGGACATCGTTAAAGGAACCAAC TCCTACTACAAGCTGCAGCTTCTGGAGGACGACAAGGAAAACAGG TATTGGATATTCAGGTCCTGGGGCCGTGTGGGTACGGTGATCGGT AGCAACAAACTGGAACAGATGCCGTCCAAGGAGGATGCCATTGAG CACTTCATGAAATTATATGAAGAAAAAACCGGGAACGCTTGGCAC TCCAAAAATTTCACGAAGTATCCCAAAAAGTTCTACCCCCTGGAG ATTGACTATGGCCAGGATGAAGAGGCAGTGAAGAAGCTGACAGTA AATCCTGGCACCAAGTCCAAGCTCCCCAAGCCAGTTCAGGACCTC ATCAAGATGATCTTTGATGTGGAAAGTATGAAGAAAGCCATGGTG GAGTATGAGATCGACCTTCAGAAGATGCCCTTGGGGAAGCTGAGC AAAAGGCAGATCCAGGCCGCATACTCCATCCTCAGTGAGGTCCAG CAGGCGGTGTCTCAGGGCAGCAGCGACTCTCAGATCCTGGATCTC TCAAATCGCTTTTACACCCTGATCCCCCACGACTTTGGGATGAAG AAGCCTCCGCTCCTGAACAATGCAGACAGTGTGCAGGCCAAGGCG GAAATGCTTGACAACCTGCTGGACATCGAGGTGGCCTACAGTCTG CTCAGGGGAGGGTCTGATGATAGCAGCAAGGATCCCATCGATGTC AACTATGAGAAGCTCAAAACTGACATTAAGGTGGTTGACAGAGAT TCTGAAGAAGCCGAGATCATCAGGAAGTATGTTAAGAACACTCAT GCAACCACACACAATGCGTATGACTTGGAAGTCATCGATATCTTT AAGATAGAGCGTGAAGGCGAATGCCAGCGTTACAAGCCCTTTAAG CAGCTTCATAACCGAAGATTGCTGTGGCACGGGTCCAGGACCACC AACTTTGCTGGGATCCTGTCCCAGGGTCTTCGGATAGCCCCGCCT GAAGCGCCCGTGACAGGCTACATGTTTGGTAAAGGGATCTATTTC GCTGACATGGTCTCCAAGAGTGCCAACTACTGCCATACGTCTCAG GGAGACCCAATAGGCTTAATCCTGTTGGGAGAAGTTGCCCTTGGA AACATGTATGAACTGAAGCACGCTTCACATATCAGCAAGTTACCC AAGGGCAAGCACAGTGTCAAAGGTTTGGGCAAAACTACCCCTGAT CCTTCAGCTAACATTAGTCTGGATGGTGTAGACGTTCCTCTTGGG ACCGGGATTTCATCTGGTGTGAATGACACCTCTCTACTATATAAC GAGTACATTGTCTATGATATTGCTCAGGTAAATCTGAAGTATCTG CTGAAACTGAAATTCAATTTTAAGACCTCCCTGTGGTAATTGGGA GAGGTAGCCGAGTCACACCCGGTGGCTCTGGTATGAATTCACCCG AAGCGCTTCTGCACCAACTCACCTGGCCGCTAAGTTGCTGATGGG TAGTACCTGTACTAAACCACCTCAGAAAGGATTTTACAGAAACGT GTTAAAGGTTTTCTCTAACTTCTCAAGTCCCTTGTTTTGTGTTGT GTCTGTGGGGAGGGGTTGTTTTGGGGTTGTTTTTGTTTTTTCTTG CCAGGTAGATAAAACTGACATAGAGAAAAGGCTGGAGAGAGATTC TGTTGCATAGACTAGTCCTATGGAAAAAACCAAGCTTCGTTAGAA TGTCTGCCTTACTGGTTTCCCCAGGGAAGGAAAAATACACTTCCA CCCTTTTTTCTAAGTGTTCGTCTTTAGTTTTGATTTTGGAAAGAT GTTAAGCATTTATTTTTAGTTAAAAATAAAAACTAATTTCATACT ATTTAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 1 | |||||||||||
| Location | 1q41-q42 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_001618 | |||||||||||
| KEGG Genes | 142 | ||||||||||||
| GeneCard | PARP1 |
| sequence | sequence of CDS | ATGGCGGAGTCTTCGGATAAGCTCTATCGAGTCGAGTACGCCAAGAGCGGGCGCGCCTCTTGCAAGAAATGCAGCGAGAGCATCCCCAAGGACTCGCTCCGGATGGCCATCATGGTGCAGTCGCCCATGTTTGATGGAAAAGTCCCACACTGGTACCACTTCTCCTGCTTCTGGAAGGTGGGCCACTCCATCCGGCACCCTGACGTTGAGGTGGATGGGTTCTCTGAGCTTCGGTGGGATGACCAGCAGAAAGTCAAGAAGACAGCGGAAGCTGGAGGAGTGACAGGCAAAGGCCAGGATGGAATTGGTAGCAAGGCAGAGAAGACTCTGGGTGACTTTGCAGCAGAGTATGCCAAGTCCAACAGAAGTACGTGCAAGGGGTGTATGGAGAAGATAGAAAAGGGCCAGGTGCGCCTGTCCAAGAAGATGGTGGACCCGGAGAAGCCACAGCTAGGCATGATTGACCGCTGGTACCATCCAGGCTGCTTTGTCAAGAACAGGGAGGAGCTGGGTTTCCGGCCCGAGTACAGTGCGAGTCAGCTCAAGGGCTTCAGCCTCCTTGCTACAGAGGATAAAGAAGCCCTGAAGAAGCAGCTCCCAGGAGTCAAGAGTGAAGGAAAGAGAAAAGGCGATGAGGTGGATGGAGTGGATGAAGTGGCGAAGAAGAAATCTAAAAAAGAAAAAGACAAGGATAGTAAGCTTGAAAAAGCCCTAAAGGCTCAGAACGACCTGATCTGGAACATCAAGGACGAGCTAAAGAAAGTGTGTTCAACTAATGACCTGAAGGAGCTACTCATCTTCAACAAGCAGCAAGTGCCTTCTGGGGAGTCGGCGATCTTGGACCGAGTAGCTGATGGCATGGTGTTCGGTGCCCTCCTTCCCTGCGAGGAATGCTCGGGTCAGCTGGTCTTCAAGAGCGATGCCTATTACTGCACTGGGGACGTCACTGCCTGGACCAAGTGTATGGTCAAGACACAGACACCCAACCGGAAGGAGTGGGTAACCCCAAAGGAATTCCGAGAAATCTCTTACCTCAAGAAATTGAAGGTTAAAAAACAGGACCGTATATTCCCCCCAGAAACCAGCGCCTCCGTGGCGGCCACGCCTCCGCCCTCCACAGCCTCGGCTCCTGCTGCTGTGAACTCCTCTGCTTCAGCAGATAAGCCATTATCCAACATGAAGATCCTGACTCTCGGGAAGCTGTCCCGGAACAAGGATGAAGTGAAGGCCATGATTGAGAAACTCGGGGGGAAGTTGACGGGGACGGCCAACAAGGCTTCCCTGTGCATCAGCACCAAAAAGGAGGTGGAAAAGATGAATAAGAAGATGGAGGAAGTAAAGGAAGCCAACATCCGAGTTGTGTCTGAGGACTTCCTCCAGGACGTCTCCGCCTCCACCAAGAGCCTTCAGGAGTTGTTCTTAGCGCACATCTTGTCCCCTTGGGGGGCAGAGGTGAAGGCAGAGCCTGTTGAAGTTGTGGCCCCAAGAGGGAAGTCAGGGGCTGCGCTCTCCAAAAAAAGCAAGGGCCAGGTCAAGGAGGAAGGTATCAACAAATCTGAAAAGAGAATGAAATTAACTCTTAAAGGAGGAGCAGCTGTGGATCCTGATTCTGGACTGGAACACTCTGCGCATGTCCTGGAGAAAGGTGGGAAGGTCTTCAGTGCCACCCTTGGCCTGGTGGACATCGTTAAAGGAACCAACTCCTACTACAAGCTGCAGCTTCTGGAGGACGACAAGGAAAACAGGTATTGGATATTCAGGTCCTGGGGCCGTGTGGGTACGGTGATCGGTAGCAACAAACTGGAACAGATGCCGTCCAAGGAGGATGCCATTGAGCACTTCATGAAATTATATGAAGAAAAAACCGGGAACGCTTGGCACTCCAAAAATTTCACGAAGTATCCCAAAAAGTTCTACCCCCTGGAGATTGACTATGGCCAGGATGAAGAGGCAGTGAAGAAGCTGACAGTAAATCCTGGCACCAAGTCCAAGCTCCCCAAGCCAGTTCAGGACCTCATCAAGATGATCTTTGATGTGGAAAGTATGAAGAAAGCCATGGTGGAGTATGAGATCGACCTTCAGAAGATGCCCTTGGGGAAGCTGAGCAAAAGGCAGATCCAGGCCGCATACTCCATCCTCAGTGAGGTCCAGCAGGCGGTGTCTCAGGGCAGCAGCGACTCTCAGATCCTGGATCTCTCAAATCGCTTTTACACCCTGATCCCCCACGACTTTGGGATGAAGAAGCCTCCGCTCCTGAACAATGCAGACAGTGTGCAGGCCAAGGTGGAAATGCTTGACAACCTGCTGGACATCGAGGTGGCCTACAGTCTGCTCAGGGGAGGGTCTGATGATAGCAGCAAGGATCCCATCGATGTCAACTATGAGAAGCTCAAAACTGACATTAAGGTGGTTGACAGAGATTCTGAAGAAGCCGAGATCATCAGGAAGTATGTTAAGAACACTCATGCAACCACACACAATGCGTATGACTTGGAAGTCATCGATATCTTTAAGATAGAGCGTGAAGGCGAATGCCAGCGTTACAAGCCCTTTAAGCAGCTTCATAACCGAAGATTGCTGTGGCACGGGTCCAGGACCACCAACTTTGCTGGGATCCTGTCCCAGGGTCTTCGGATAGCCCCGCCTGAAGCGCCCGTGACAGGCTACATGTTTGGTAAAGGGATCTATTTCGCTGACATGGTCTCCAAGAGTGCCAACTACTGCCATACGTCTCAGGGAGACCCAATAGGCTTAATCCTGTTGGGAGAAGTTGCCCTTGGAAACATGTATGAACTGAAGCACGCTTCACATATCAGCAAGTTACCCAAGGGCAAGCACAGTGTCAAAGGTTTGGGCAAAACTACCCCTGATCCTTCAGCTAACATTAGTCTGGATGGTGTAGACGTTCCTCTTGGGACCGGGATTTCATCTGGTGTGAATGACACCTCTCTACTATATAACGAGTACATTGTCTATGATATTGCTCAGGTAAATCTGAAGTATCTGCTGAAACTGAAATTCAATTTTAAGACCTCCCTGTGGTAA |
| sequence of protein | MAESSDKLYRVEYAKSGRASCKKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDDQQKVKKTAEAGGVTGKGQDGIGSKAEKTLGDFAAEYAKSNRSTCKGCMEKIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATEDKEALKKQLPGVKSEGKRKGDEVDGVDEVAKKKSKKEKDKDSKLEKALKAQNDLIWNIKDELKKVCSTNDLKELLIFNKQQVPSGESAILDRVADGMVFGALLPCEECSGQLVFKSDAYYCTGDVTAWTKCMVKTQTPNRKEWVTPKEFREISYLKKLKVKKQDRIFPPETSASVAATPPPSTASAPAAVNSSASADKPLSNMKILTLGKLSRNKDEVKAMIEKLGGKLTGTANKASLCISTKKEVEKMNKKMEEVKEANIRVVSEDFLQDVSASTKSLQELFLAHILSPWGAEVKAEPVEVVAPRGKSGAALSKKSKGQVKEEGINKSEKRMKLTLKGGAAVDPDSGLEHSAHVLEKGGKVFSATLGLVDIVKGTNSYYKLQLLEDDKENRYWIFRSWGRVGTVIGSNKLEQMPSKEDAIEHFMKLYEEKTGNAWHSKNFTKYPKKFYPLEIDYGQDEEAVKKLTVNPGTKSKLPKPVQDLIKMIFDVESMKKAMVEYEIDLQKMPLGKLSKRQIQAAYSILSEVQQAVSQGSSDSQILDLSNRFYTLIPHDFGMKKPPLLNNADSVQAKVEMLDNLLDIEVAYSLLRGGSDDSSKDPIDVNYEKLKTDIKVVDRDSEEAEIIRKYVKNTHATTHNAYDLEVIDIFKIEREGECQRYKPFKQLHNRRLLWHGSRTTNFAGILSQGLRIAPPEAPVTGYMFGKGIYFADMVSKSANYCHTSQGDPIGLILLGEVALGNMYELKHASHISKLPKGKHSVKGLGKTTPDPSANISLDGVDVPLGTGISSGVNDTSLLYNEYIVYDIAQVNLKYLLKLKFNFKTSLW | |
| Database link | RefSeq | NM_001618 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008] |
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