Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU007266 |
| Korean Unigene Clone | IRAU-19-F06 | |
| Original Clone | IRAL-11-M13 | |
| Vector | pOTB7 | |
| Gene | CDKN2D | |
| Gene Description | cyclin dependent kinase inhibitor 2D | |
| Clone sequence size | 1146 (bp) | |
| Fullness | F | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 1146 |
| Sequence | GGCGAGGAGGAGGGAGGGCCGCCAGTGTCGACATGCTGCTGGAGG AGGTTCGCGCCGGCGACCGGCTGAGTGGGGCGGCGGCCCGGGGCG ACGTGCAGGAGGTGCGCCGCCTTCTGCACCGCGAGCTGGTGCATC CCGACGCCCTCAACCGCTTCGGCAAGACGGCGCTGCAGGTCATGA TGTTTGGCAGCACCGCCATCGCCCTGGAGCTGCTGAAGCAAGGTG CCAGCCCCAATGTCCAGGACACCTCCGGTACCAGTCCAGTCCATG ACGCAGCCCGCACTGGATTCCTGGACACCCTGAAGGTCCTAGTGG AGCACGGGGCTGATGTCAACGTGCCTGATGGCACCGGGGCACTTC CAATCCATCTGGCAGTTCAAGAGGGTCACACTGCTGTGGTCAGCT TTCTGGCAGCTGAATCTGATCTCCATCGCAGGGACGCCAGGGGTC TCACACCCTTGGAGCTGGCACTGCAGAGAGGGGCTCAGGACCTCG TGGACATCCTGCAGGGCCACATGGTGGCCCCGCTGTGATCTGGGG TCACCCTCTCCAGCAAGAGAACCCCGTGGGGTTATGTATCAGAAG AGAGGGGAAGAAACACTTTCTCTTCTTGTTTCTCCTGCCCACTGC TGCAGTAGGGGAGGAGCACAGTTTGTGGCTTATAGGTGTTGGTTT TGGGGGTGTGAGTGTTTGGGGGACGTTTCTCATTTGTTTTTCTCA CTCCTTTTGGTGTGTTGGACAGAGAAGGGCTCCTGCAGGCCACAG CCACCTAAACGGTTCAGTTTCTTCTGCGCCTCAGGCTGCTGGGGC CTCAGACGAGACCCAAGGGCAGAGCATTTAAGAGTGAAGTCATGA CCTCCAGGGAGCCTAGAAGCTGGTGGCCTTGGCCGGCTGTGCTCA GAGACCTGAAGTGTGCACGTTGCTTCAGGCATGGGGGGTGGGGGG AGCGTCCCAAATCAATAAGAAGGTAGAATGAGTTATGAGTTATTC ATATTCTGTTGGAAGCTTGTTTTCCAGTCTCTTGTACAGCGTTTT AAAAGAAATGGATTCTATTTATTATGCTTTATTGGAAAAAATGTT GTAATAATTTAATGTTTTTACCCATTAAATTAAGACTTGTGCATG ATCAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 19 | |||||||||||
| Location | 19p13 | ||||||||||||
| Strand |
|
||||||||||||
| Database links | RefSeq | NM_079421 | |||||||||||
| KEGG Genes | 1032 | ||||||||||||
| GeneCard | CDKN2D |
| sequence | sequence of CDS | ATGCTGCTGGAGGAGGTTCGCGCCGGCGACCGGCTGAGTGGGGCGGCGGCCCGGGGCGACGTGCAGGAGGTGCGCCGCCTTCTGCACCGGGAGCTGGTGCATCCCGACGCCCTCAACCGCTTCGGCAAGACGGCGCTGCAGGTCATGATGTTTGGCAGCACCGCCATCGCCCTGGAGCTGCTGAAGCAAGGTGCCAGCCCCAATGTCCAGGACACCTCCGGTACCAGTCCAGTCCATGACGCAGCCCGCACTGGATTCCTGGACACCCTGAAGGTCCTAGTGGAGCACGGGGCTGATGTCAACGTGCCTGATGGCACCGGGGCACTTCCAATCCATCTGGCAGTTCAAGAGGGTCACACTGCTGTGGTCAGCTTTCTGGCAGCTGAATCTGATCTCCATCGCAGGGACGCCAGGGGTCTCACACCCTTGGAGCTGGCACTGCAGAGAGGGGCTCAGGACCTCGTGGACATCCTGCAGGGCCACATGGTGGCCCCGCTGTGA |
| sequence of protein | MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL | |
| Database link | RefSeq | NM_079421 |
| UniProt | ||
| CCDS |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
|
| Disease | Summary |
| The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008] |
|
|||||||||||
