Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU008042 |
| Korean Unigene Clone | IRAU-27-G02 | |
| Original Clone | IRAL-04-H14 | |
| Vector | pOTB7 | |
| Gene | ITGAL | |
| Gene Description | integrin subunit alpha L | |
| Clone sequence size | 4673 (bp) | |
| Fullness | F | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 4673 |
| Sequence | GCCAAAGGGCATGATCATTTTCCTCTTTCACCCTGTCTAGGTTGC CAGCAAATCCCACGGGCCTCCTGACGCTGCCCCTGGGGCCACAGG TCCCTCGAGTGCTGGAAGGATGAAGGATTCCTGCATCACTGTGAT GGCCATGGCGCTGCTGTCTGGGTTCTTTTTCTTCGCGCCGGCCTC GAGCTACAACCTGGACGTGCGGGGCGCGCGGAGCTTCTCCCCACC GCGCGCCGGGAGGCACTTTGGATACCGCGTCCTGCAGGTCGGAAA CGGGGTCATCGTGGGAGCTCCAGGGGAGGGGAACAGCACAGGAAG CCTCTATCAGTGCCAGTCGGGCACAGGACACTGCCTGCCAGTCAC CCTGAGAGGTTCCAACTATACCTCCAAGTACTTGGGAATGACCTT GGCAACAGACCCCACAGATGGAAGCATTTTGTTTGCTGCTGTTCA GTTTTCCACAAGCTACAAAACAGAATTTGATTTCTCAGATTATGT TAAACGGAAGGACCCTGATGCTCTGCTGAAGCATGTAAAGCACAT GTTGCTGTTGACCAATACCTTTGGTGCCATCAATTATGTCGCGAC AGAGGTGTTCCGGGAGGAGCTGGGGGCCCGGCCAGATGCCACCAA AGTGCTTATCATCATCACGGATGGGGAGGCCACTGACAGTGGCAA CATCGATGCGGCCAAAGACATCATCCGCTACATCATCGGGATTGG AAAGCATTTTCAGACCAAGGAGAGTCAGGAGACCCTCCACAAATT TGCATCAAAACCCGCGAGCGAGTTTGTGAAAATTCTGGACACATT TGAGAAGCTGAAAGATCTATTCACTGAGCTGCAGAAGAAGATCTA TGTCATTGAGGGCACAAGCAAACAGGACCTGACTTCCTTCAACAT GGAGCTGTCCTCCAGCGGCATCAGTGCTGACCTCAGCAGGGGCCA TGCAGTCGTGGGGGCAGTAGGAGCCAAGGACTGGGCTGGGGGCTT TCTTGACCTGAAGGCAGACCTGCAGGATGACACATTTATTGGGAA TGAACCATTGACACCAGAAGTGAGAGCAGGCTATTTGGGTTACAC CGTGACCTGGCTGCCCTCCCGGCAAAAGACTTCGTTGCTGGCCTC GGGAGCCCCTCGATACCAGCACATGGGCCGAGTGCTGCTGTTCCA AGAGCCACAGGGCGGAGGACACTGGAGCCAGGTCCAGACAATCCA TGGGACCCAGATTGGCTCTTATTTCGGTGGGGAGCTGTGTGGCGT CGACGTGGACCAAGATGGGGAGACAGAGCTGCTGCTGATTGGTGC CCCACTGTTCTATGGGGAGCAGAGAGGAGGCCGGGTGTTTATCTA CCAGAGAAGACAGTTGGGGTTTGAAGAAGTCTCAGAGCTGCAGGG GGACCCCGGCTACCCACTCGGGCGGTTTGGAGAAGCCATCACTGC TCTGACAGACATCAACGGCGATGGGCTGGTAGACGTGGCTGTGGG GGCCCCTCTGGAGGAGCAGGGGGCTGTGTACATCTTCAATGGGAG GCACGGGGGGCTTAGTCCCCAGCCAAGTCAGCGGATAGAAGGGAC CCAAGTGCTCTCAGGAATTCAGTGGTTTGGACGCTCCATCCATGG GGTGAAGGACCTTGAAGGGGATGGCTTGGCAGATGTGGCTGTGGG GGCTGAGAGCCAGATGATCGTGCTGAGCTCCCGGCCCGTGGTGGA TATGGTCACCCTGATGTCCTTCTCTCCAGCTGAGATCCCAGTGCA TGAAGTGGAGTGCTCCTATTCAACCAGTAACAAGATGAAAGAAGG AGTTAATATCACAATCTGTTTCCAGATCAAGTCTCTCATCCCCCA GTTCCAAGGCCGCCTGGTTGCCAATCTCACTTACACTCTGCAGCT GGATGGCCACCGGACCAGAAGACGGGGGTTGTTCCCAGGAGGGAG ACATGAACTCAGAAGGAATATAGCTGTCACCACCAGCATGTCATG CACTGACTTCTCATTTCATTTCCCGGTATGTGTTCAAGACCTCAT CTCCCCCATCAATGTTTCCCTGAATTTCTCTCTTTGGGAGGAGGA AGGGACACCGAGGGACCAAAGGGCGGGCAAGGACATACCGCCCAT CCTGAGACCCTCCCTGCACTCGGAAACCTGGGAGATCCCTTTTGA GAAGAACTGTGGGGAGGACAAGAAGTGTGAGGCAAACTTGAGAGT GTCCTTCTCTCCTGCAAGATCCAGAGCCCTGCGTCTAACTGCTTT TGCCAGCCTCTCTGTGGAGCTGAGCCTGAGTAACTTGGAAGAAGA TGCTTACTGGGTCCAGCTGGACCTGCACTTCCCCCCGGGACTCTC CTTCCGCAAGGTGGAGATGCTGAAGCCCCATAGCCAGATACCTGT GAGCTGCGAGGAGCTTCCTGAAGAGTCCAGGCTTCTGTCCAGGGC ATTATCTTGCAATGTGAGCTCTCCCATCTTCAAAGCAGGCCACTC GGTTGCTCTGCAGATGATGTTTAATACACTGGTAAACAGCTCCTG GGGGGACTCGGTTGAATTGCACGCCAATGTGACCTGTAACAATGA GGACTCAGACCTCCTGGAGGACAACTCAGCCACTACCATCATCCC CATCCTGTACCCCATCAACATCCTCATCCAGGACCAAGAAGACTC CACACTCTATGTCAGTTTCACCCCCAAAGGCCCCAAGATCCACCA AGTCAAGCACATGTACCAGGTGAGGATCCAGCCTTCCATCCACGA CCACAACATACCCACCCTGGAGGCTGTGGTTGGGGTGCCACAGCC TCCCAGCGAGGGGCCCATCACACACCAGTGGAGCGTGCAGATGGA GCCTCCCGTGCCCTGCCACTATGAGGATCTGGAGAGGCTCCCGGA TGCAGCTGAGCCTTGTCTCCCCGGAGCCCTGTTCCGCTGCCCTGT TGTCTTCAGGCAGGAGATCCTCGTCCAAGTGATCGGGACTCTGGA GCTGGTGGGAGAGATCGAGGCCTCTTCCATGTTCAGCCTCTGCAG CTCCCTCTCCATCTCCTTCAACAGCAGCAAGCATTTCCACCTCTA TGGCAGCAACGCCTCCCTGGCCCAGGTTGTCATGAAGGTTGACGT GGTGTATGAGAAGCAGATGCTCTACCTCTACGTGCTGAGCGGCAT CGGGGGGCTGCTGCTGCTGCTGCTCATTTTCATAGTGCTGTACAA GGTTGGTTTCTTCAAACGGAACCTGAAGGAGAAGATGGAGGCTGG CAGAGGTGTCCCGAATGGAATCCCTGCAGAAGACTCTGAGCAGCT GGCATCTGGGCAAGAGGCTGGGGATCCCGGCTGCCTGAAGCCCCT CCATGAGAAGGACTCTGAGAGTGGTGGTGGCAAGGACTGAGTCCA GGCCTGTGAGGTGCAGAGTGCCCAGAACTGGACTCAGGATGCCCA GGGCCACTCTGCCTCTGCCTGCATTCTGCCGTGTGCCCTCGGGCG AGTCACTGCCTCTCCCTGGCCCTCAGTTTCCCTATCTCGAACATG GAACTCATTCCTGCCTGTCTCCTTTGCAGGCTCATAGGGAAGACC TGCTGAGGGACCAGCCAAGAGGGCTGCAAAAGTGAGGGCTTGTCA TTACCAGACGGTTCACCAGCCTCTCTTGGTTTCCTTCCTTGGAAG AGAATGTCTGATCTAAATGTGGAGAAACTGTAGTCTCAGGACCTA GGGATGTTCTGGCCCTCACCCCTGCCCTGGGATGTCCACAGATGC CTCCACCCCCCAGAACCTGTCCTTGCACACTCCCCTGCACTGGAG TCCAGTCTCTTCTGCTGGCAGAAAGCAAATGTGACCTGTGTCACT ACGTGACTGTGGCACACGCCTTGTTCTTGGCCAAAGACCAAATTC CTTGGCATGCCTTCCAGCACCCTGCAAAATGAGACCCTCGTGGCC TTCCCCAGCCTCTTCTAGAGCCGTGATGCCTCCCTGTTGAAGCTC TGGTGACACCAGCCTTTCTCCCAGGCCAGGCTCCTTCCTGTCTTC CTGCATTCACCCAGACAGCTCCCTCTGCCTGAACCTTCCATCTCG CCACCCCTCCTTCCTTGACCAGCAGATCCCAGCTCACGTCACACT TGGTTGGGTCCTCACATCTTTCACACTTCCACCAGCCTGCACTAC TCCCTCAAAGCACACGTCATGTTTCTTCATCCGGCAGCCTGGATG TTTTTTCCCTGTTTAATGATTGACGTACTTAGCAGCTATCTCTCA GTGAACTGTGAGGGTAAAGGCTATACTTGTCTTGTTCACCTTGGG ATGATGCCTCATGATATGTCAGGGCGTGGGACATCTAGTAGGTGC TTGACATAATTTCACTGAATTAATGACAGAGCCAGTGGGAAGATA CAGAAAAAGAGGGGCTGGGCTGGGCGCGGTGGTTCACGCCTGTAA TCCCAGCACTTTGGGAGGCCAAGGAGGGTGGATCACCTGAGGTCA GGAGTTAGAGGCCAGCCTGGCGAAACCCCATCTCTACTAAAAATA CAAAATCCAGGCGTGGTGGCACACACCTGTAGTCCCAGCTACTCA GGAGGTTGAGGTAGGAGAATTGCTTGAACCTGGGAGGTGGAGGTT GCAGTGAGCCAAGATTGCGCCATTGCACTCCAGCCTGGGCAACAC AGCGAGACTCCGTCTCAAGGAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 16 | |||||||||||
| Location | 16p11.2 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_001114380 | |||||||||||
| KEGG Genes | 3683 | ||||||||||||
| GeneCard | ITGAL |
| sequence | sequence of CDS | ATGAAGGATTCCTGCATCACTGTGATGGCCATGGCGCTGCTGTCTGGGTTCTTTTTCTTCGCGCCGGCCTCGAGCTACAACCTGGACGTGCGGGGCGCGCGGAGCTTCTCCCCACCGCGCGCCGGGAGGCACTTTGGATACCGCGTCCTGCAGGTCGGAAACGGGGTCATCGTGGGAGCTCCAGGGGAGGGGAACAGCACAGGAAGCCTCTATCAGTGCCAGTCGGGCACAGGACACTGCCTGCCAGTCACCCTGAGAGGTTCCAACTATACCTCCAAGTACTTGGGAATGACCTTGGCAACAGACCCCACAGATGGAAGCATTTTGTTTGCTGCTGTTCAGTTTTCCACAAGCTACAAAACAGAATTTGATTTCTCAGATTATGTTAAACGGAAGGACCCTGATGCTCTGCTGAAGCATGTAAAGCACATGTTGCTGTTGACCAATACCTTTGGTGCCATCAATTATGTCGCGACAGAGGTGTTCCGGGAGGAGCTGGGGGCCCGGCCAGATGCCACCAAAGTGCTTATCATCATCACGGATGGGGAGGCCACTGACAGTGGCAACATCGATGCGGCCAAAGACATCATCCGCTACATCATCGGGATTGGAAAGCATTTTCAGACCAAGGAGAGTCAGGAGACCCTCCACAAATTTGCATCAAAACCCGCGAGCGAGTTTGTGAAAATTCTGGACACATTTGAGAAGCTGAAAGATCTATTCACTGAGCTGCAGAAGAAGATCTATGTCATTGAGGGCACAAGCAAACAGGACCTGACTTCCTTCAACATGGAGCTGTCCTCCAGCGGCATCAGTGCTGACCTCAGCAGGGGCCATGCAGTCGTGGGGGCAGTAGGAGCCAAGGACTGGGCTGGGGGCTTTCTTGACCTGAAGGCAGACCTGCAGGATGACACATTTATTGGGAATGAACCATTGACACCAGAAGTGAGAGCAGGCTATTTGGGTTACACCGTGACCTGGCTGCCCTCCCGGCAAAAGACTTCGTTGCTGGCCTCGGGAGCCCCTCGATACCAGCACATGGGCCGAGTGCTGCTGTTCCAAGAGCCACAGGGCGGAGGACACTGGAGCCAGGTCCAGACAATCCATGGGACCCAGATTGGCTCTTATTTCGGTGGGGAGCTGTGTGGCGTCGACGTGGACCAAGATGGGGAGACAGAGCTGCTGCTGATTGGTGCCCCACTGTTCTATGGGGAGCAGAGAGGAGGCCGGGTGTTTATCTACCAGAGAAGACAGTTGGGGTTTGAAGAAGTCTCAGAGCTGCAGGGGGACCCCGGCTACCCACTCGGGCGGTTTGGAGAAGCCATCACTGCTCTGACAGACATCAACGGCGATGGGCTGGTAGACGTGGCTGTGGGGGCCCCTCTGGAGGAGCAGGGGGCTGTGTACATCTTCAATGGGAGGCACGGGGGGCTTAGTCCCCAGCCAAGTCAGCGGATAGAAGGGACCCAAGTGCTCTCAGGAATTCAGTGGTTTGGACGCTCCATCCATGGGGTGAAGGACCTTGAAGGGGATGGCTTGGCAGATGTGGCTGTGGGGGCTGAGAGCCAGATGATCGTGCTGAGCTCCCGGCCCGTGGTGGATATGGTCACCCTGATGTCCTTCTCTCCAGCTGAGATCCCAGTGCATGAAGTGGAGTGCTCCTATTCAACCAGTAACAAGATGAAAGAAGGAGTTAATATCACAATCTGTTTCCAGATCAAGTCTCTCATCCCCCAGTTCCAAGGCCGCCTGGTTGCCAATCTCACTTACACTCTGCAGCTGGATGGCCACCGGACCAGAAGACGGGGGTTGTTCCCAGGAGGGAGACATGAACTCAGAAGGAATATAGCTGTCACCACCAGCATGTCATGCACTGACTTCTCATTTCATTTCCCGGTATGTGTTCAAGACCTCATCTCCCCCATCAATGTTTCCCTGAATTTCTCTCTTTGGGAGGAGGAAGGGACACCGAGGGACCAAAGGGCGGGCAAGGACATACCGCCCATCCTGAGACCCTCCCTGCACTCGGAAACCTGGGAGATCCCTTTTGAGAAGAACTGTGGGGAGGACAAGAAGTGTGAGGCAAACTTGAGAGTGTCCTTCTCTCCTGCAAGATCCAGAGCCCTGCGTCTAACTGCTTTTGCCAGCCTCTCTGTGGAGCTGAGCCTGAGTAACTTGGAAGAAGATGCTTACTGGGTCCAGCTGGACCTGCACTTCCCCCCGGGACTCTCCTTCCGCAAGGTGGAGATGCTGAAGCCCCATAGCCAGATACCTGTGAGCTGCGAGGAGCTTCCTGAAGAGTCCAGGCTTCTGTCCAGGGCATTATCTTGCAATGTGAGCTCTCCCATCTTCAAAGCAGGCCACTCGGTTGCTCTGCAGATGATGTTTAATACACTGGTAAACAGCTCCTGGGGGGACTCGGTTGAATTGCACGCCAATGTGACCTGTAACAATGAGGACTCAGACCTCCTGGAGGACAACTCAGCCACTACCATCATCCCCATCCTGTACCCCATCAACATCCTCATCCAGGACCAAGAAGACTCCACACTCTATGTCAGTTTCACCCCCAAAGGCCCCAAGATCCACCAAGTCAAGCACATGTACCAGGTGAGGATCCAGCCTTCCATCCACGACCACAACATACCCACCCTGGAGGCTGTGGTTGGGGTGCCACAGCCTCCCAGCGAGGGGCCCATCACACACCAGTGGAGCGTGCAGATGGAGCCTCCCGTGCCCTGCCACTATGAGGATCTGGAGAGGCTCCCGGATGCAGCTGAGCCTTGTCTCCCCGGAGCCCTGTTCCGCTGCCCTGTTGTCTTCAGGCAGGAGATCCTCGTCCAAGTGATCGGGACTCTGGAGCTGGTGGGAGAGATCGAGGCCTCTTCCATGTTCAGCCTCTGCAGCTCCCTCTCCATCTCCTTCAACAGCAGCAAGCATTTCCACCTCTATGGCAGCAACGCCTCCCTGGCCCAGGTTGTCATGAAGGTTGACGTGGTGTATGAGAAGCAGATGCTCTACCTCTACGTGCTGAGCGGCATCGGGGGGCTGCTGCTGCTGCTGCTCATTTTCATAGTGCTGTACAAGGTTGGTTTCTTCAAACGGAACCTGAAGGAGAAGATGGAGGCTGGCAGAGGTGTCCCGAATGGAATCCCTGCAGAAGACTCTGAGCAGCTGGCATCTGGGCAAGAGGCTGGGGATCCCGGCTGCCTGAAGCCCCTCCATGAGAAGGACTCTGAGAGTGGTGGTGGCAAGGACTGA |
| sequence of protein | MKDSCITVMAMALLSGFFFFAPASSYNLDVRGARSFSPPRAGRHFGYRVLQVGNGVIVGAPGEGNSTGSLYQCQSGTGHCLPVTLRGSNYTSKYLGMTLATDPTDGSILFAAVQFSTSYKTEFDFSDYVKRKDPDALLKHVKHMLLLTNTFGAINYVATEVFREELGARPDATKVLIIITDGEATDSGNIDAAKDIIRYIIGIGKHFQTKESQETLHKFASKPASEFVKILDTFEKLKDLFTELQKKIYVIEGTSKQDLTSFNMELSSSGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIGNEPLTPEVRAGYLGYTVTWLPSRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDVDQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLGFEEVSELQGDPGYPLGRFGEAITALTDINGDGLVDVAVGAPLEEQGAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIHGVKDLEGDGLADVAVGAESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKMKEGVNITICFQIKSLIPQFQGRLVANLTYTLQLDGHRTRRRGLFPGGRHELRRNIAVTTSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPILRPSLHSETWEIPFEKNCGEDKKCEANLRVSFSPARSRALRLTAFASLSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTCNNEDSDLLEDNSATTIIPILYPINILIQDQEDSTLYVSFTPKGPKIHQVKHMYQVRIQPSIHDHNIPTLEAVVGVPQPPSEGPITHQWSVQMEPPVPCHYEDLERLPDAAEPCLPGALFRCPVVFRQEILVQVIGTLELVGEIEASSMFSLCSSLSISFNSSKHFHLYGSNASLAQVVMKVDVVYEKQMLYLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEAGRGVPNGIPAEDSEQLASGQEAGDPGCLKPLHEKDSESGGGKD | |
| Database link | RefSeq | NM_001114380 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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