Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU010251 |
| Korean Unigene Clone | IRAU-50-G03 | |
| Original Clone | IRAL-14-G21 | |
| Vector | pOTB7 | |
| Gene | IL1RN | |
| Gene Description | interleukin 1 receptor antagonist | |
| Clone sequence size | 1707 (bp) | |
| Fullness | F | |
| Mutation | 241 | |
| Amino acid - mutation | GCT(A)-> GCC(A) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 1707 |
| Sequence | GGAAGACCTCCTGTCCTATCAGGCCCTCCCCATGGCTTTAGAGAC GATCTGCCGACCCTCTGGGAGAAAATCCAGCAAGATGCAAGCCTT CAGAATCTGGGATGTTAACCAGAAGACCTTCTATCTGAGGAACAA CCAACTAGTTGCCGGATACTTGCAAGGACCAAATGTCAATTTAGA AGAAAAGATAGATGTGGTACCCATTGAGCCTCATGCTCTGTTCTT GGGAATCCATGGAGGGAAGATGTGCCTGTCCTGTGTCAAGTCTGG TGATGAGACCAGACTCCAGCTGGAGGCAGTTAACATCACTGACCT GAGCGAGAACAGAAAGCAGGACAAGCGCTTCGCCTTCATCCGCTC AGACAGTGGCCCCACCACCAGTTTTGAGTCTGCCGCCTGCCCCGG TTGGTTCCTCTGCACAGCGATGGAAGCTGACCAGCCCGTCAGCCT CACCAATATGCCTGACGAAGGCGTCATGGTCACCAAATTCTACTT CCAGGAGGACGAGTAGTACTGCCCAGGCCTGCCTGTTCCCATTCT TGCATGGCAAGGACTGCAGGGACTGCCAGTCCCCCTGCCCCAGGG CTCCCGGCTATGGGGGCACTGAGGACCAGCCATTGAGGGGTGGAC CCTCAGAAGGCGTCACAACAACCTGGTCACAGGACTCTGCCTCCT CTTCAACTGACCAGCCTCCATGCTGCCTCCAGAATGGTCTTTCTA ATGTGTGAATCAGAGCACAGCAGCCCCTGCACAAAGCCCTTCCAT GTCGCCTCTGCATTCAGGATCAAACCCCGACCACCTGCCCAACCT GCTCTCCTCTTGCCACTGCCTCTTCCTCCCTCATTCCACCTTCCC ATGCCCTGGATCCATCAGGCCACTTGATGACCCCCAACCAAGTGG CTCCCACACCCTGTTTTACAAAAAAGAAAAGACCAGTCCATGAGG GAGGTTTTTAAGGGTTTGTGGAAAATGAAAATTAGGATTTCATGA TTTTTTTTTTTCAGTCCCCGTGAAGGAGAGCCCTTCATTTGGAGA TTATGTTCTTTCGGGGAGAGGCTGAGGACTTAAAATATTCCTGCA TTTGTGAAATGATGGTGAAAGTAAGTGGTAGCTTTTCCCTTCTTT TTCTTCTTTTTTTGTGATGTCCCAACTTGTAAAAATTAAAAGTTA TGGTACTATGTTAGCCCCATAATTTTTTTTTTCCTTTTAAAACAC TTCCATAATCTGGACTCCTCTGTCCAGGCACTGCTGCCCAGCCTC CAAGCTCCATCTCCACTCCAGATTTTTTACAGCTGCCTGCAGTAC TTTACCTCCTATCAGAAGTTTCTCAGCTCCCAAGGCTCTGAGCAA ATGTGGCTCCTGGGGGTTCTTTCTTCCTCTGCTGAAGGAATAAAT TGCTCCTTGACATTGTAGAGCTTCTGGCACTTGGAGACTTGTATG AAAGATGGCTGTGCCTCTGCCTGTCTCCCCCACCAGGCTGGGAGC TCTGCAGAGCAGGAAACATGACTCGTATATGTCTCAGGTCCCTGC AGGGCCAAGCACCTAGCCTCGCTCTTGGCAGGTACTCAGCGAATG AATGCTGTATATGTTGGGTGCAAAGTTCCCTACTTCCTGTGACTT CAGCTCTGTTTTACAATAAAATCTTGAAAATGCCTAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 2 | |||||||||||
| Location | 2q14.2 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_000577 | |||||||||||
| KEGG Genes | 3557 | ||||||||||||
| GeneCard | IL1RN |
| sequence | sequence of CDS | ATGGCTTTAGAGACGATCTGCCGACCCTCTGGGAGAAAATCCAGCAAGATGCAAGCCTTCAGAATCTGGGATGTTAACCAGAAGACCTTCTATCTGAGGAACAACCAACTAGTTGCTGGATACTTGCAAGGACCAAATGTCAATTTAGAAGAAAAGATAGATGTGGTACCCATTGAGCCTCATGCTCTGTTCTTGGGAATCCATGGAGGGAAGATGTGCCTGTCCTGTGTCAAGTCTGGTGATGAGACCAGACTCCAGCTGGAGGCAGTTAACATCACTGACCTGAGCGAGAACAGAAAGCAGGACAAGCGCTTCGCCTTCATCCGCTCAGACAGTGGCCCCACCACCAGTTTTGAGTCTGCCGCCTGCCCCGGTTGGTTCCTCTGCACAGCGATGGAAGCTGACCAGCCCGTCAGCCTCACCAATATGCCTGACGAAGGCGTCATGGTCACCAAATTCTACTTCCAGGAGGACGAGTAG |
| sequence of protein | MALETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE | |
| Database link | RefSeq | NM_000577 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jan 2016] |
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