Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU011546 |
| Korean Unigene Clone | IRAU-64-C02 | |
| Original Clone | IRAL-28-J03 | |
| Vector | pOTB7 | |
| Gene | DLK1 | |
| Gene Description | delta like non-canonical Notch ligand 1 | |
| Clone sequence size | 1568 (bp) | |
| Fullness | F | |
| Mutation | 766,982 | |
| Amino acid - mutation | ATT(I)-> ATC(I),AGC(S)-> AAC(N) | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 1568 |
| Sequence | GCGCAGCGCGCAGCCCGGTGCAGCCCTGGCTTTCCCCTCGCTGCG CGCCCGCGCCCCCTTTCGCGTCCGCAACCAGAAGCCCAGTGCGGC GCCAGGAGCCGGACCCGCGCCCGCACCGCTCCCGGGACCGCGACC CCGGCCGCCCAGAGATGACCGCGACCGAAGCCCTCCTGCGCGTCC TCTTGCTCCTGCTGGCTTTCGGCCACAGCACCTATGGGGCTGAAT GCTTCCCGGCCTGCAACCCCCAAAATGGATTCTGCGAGGATGACA ATGTTTGCAGGTGCCAGCCTGGCTGGCAGGGTCCCCTTTGTGACC AGTGCGTGACCTCTCCCGGCTGCCTTCACGGACTCTGTGGAGAAC CCGGGCAGTGCATTTGCACCGACGGCTGGGACGGGGAGCTCTGTG ATAGAGATGTTCGGGCCTGCTCCTCGGCCCCCTGTGCCAACAACG GGACCTGCGTGAGCCTGGACGATGGCCTCTATGAATGCTCCTGTG CCCCCGGGTACTCGGGAAAGGACTGCCAGAAAAAGGACGGGCCCT GTGTGATCAACGGCTCCCCCTGCCAGCACGGAGGCACCTGCGTGG ATGATGAGGGCCGGGCCTCCCATGCCTCCTGCCTGTGCCCCCCTG GCTTCTCAGGCAATTTCTGCGAGATCGTGGCCAACAGCTGCACCC CCAACCCATGCGAGAACGACGGCGTCTGCACTGACATCGGGGGCG ACTTCCGCTGCCGGTGCCCAGCCGGCTTCATCGACAAGACCTGCA GCCGCCCGGTGACCAACTGCGCCAGCAGCCCGTGCCAGAACGGGG GCACCTGCCTGCAGCACACCCAGGTGAGCTACGAGTGTCTGTGCA AGCCCGAGTTCACAGGTCTCACCTGTGTCAAGAAGCGCGCGCTGA GCCCCCAGCAGGTCACCCGTCTGCCCAACGGCTATGGGCTGGCCT ACCGCCTGACCCCTGGGGTGCACGAGCTGCCGGTGCAGCAGCCGG AGCACCGCATCCTGAAGGTGTCCATGAAAGAGCTCAACAAGAAAA CCCCTCTCCTCACCGAGGGCCAGGCCATCTGCTTCACCATCCTGG GCGTGCTCACCAGCCTGGTGGTGCTGGGCACTGTGGGTATCGTCT TCCTCAACAAGTGCGAGACCTGGGTGTCCAACCTGCGCTACAACC ACATGCTGCGGAAGAAGAAGAACCTGCTGCTTCAGTACAACAGCG GGGAGGACCTGGCCGTCAACATCATCTTCCCCGAGAAGATCGACA TGACCACCTTCAGCAAGGAGGCCGGCGACGAGGAGATCTAAGCAG CGTTCCCACAGCCCCCTCTAGATTCTTGGAGTTCCTCAGAGCTTA CTATACGCGGTCTGTCCTAATCTTTGTGGTGTTCGCTATCTCTTG TGTCAAATCTGGTGAACGCTACGCTTACATATATTGTCTTTGTGC TGCTGTGTGACAAACGCAATGCAAAAACAATCCTCTTTCTCTCTC TTAATGCATGATACAGAATAATAATAAGAATTTCATCTTTAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 14 | |||||||||||
| Location | 14q32 | ||||||||||||
| Strand |
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| Database links | RefSeq | NM_003836 | |||||||||||
| KEGG Genes | 8788 | ||||||||||||
| GeneCard | DLK1 |
| sequence | sequence of CDS | ATGACCGCGACCGAAGCCCTCCTGCGCGTCCTCTTGCTCCTGCTGGCTTTCGGCCACAGCACCTATGGGGCTGAATGCTTCCCGGCCTGCAACCCCCAAAATGGATTCTGCGAGGATGACAATGTTTGCAGGTGCCAGCCTGGCTGGCAGGGTCCCCTTTGTGACCAGTGCGTGACCTCTCCCGGCTGCCTTCACGGACTCTGTGGAGAACCCGGGCAGTGCATTTGCACCGACGGCTGGGACGGGGAGCTCTGTGATAGAGATGTTCGGGCCTGCTCCTCGGCCCCCTGTGCCAACAACAGGACCTGCGTGAGCCTGGACGATGGCCTCTATGAATGCTCCTGTGCCCCCGGGTACTCGGGAAAGGACTGCCAGAAAAAGGACGGGCCCTGTGTGATCAACGGCTCCCCCTGCCAGCACGGAGGCACCTGCGTGGATGATGAGGGCCGGGCCTCCCATGCCTCCTGCCTGTGCCCCCCTGGCTTCTCAGGCAATTTCTGCGAGATCGTGGCCAACAGCTGCACCCCCAACCCATGCGAGAACGACGGCGTCTGCACTGACATTGGGGGCGACTTCCGCTGCCGGTGCCCAGCCGGCTTCATCGACAAGACCTGCAGCCGCCCGGTGACCAACTGCGCCAGCAGCCCGTGCCAGAACGGGGGCACCTGCCTGCAGCACACCCAGGTGAGCTACGAGTGTCTGTGCAAGCCCGAGTTCACAGGTCTCACCTGTGTCAAGAAGCGCGCGCTGAGCCCCCAGCAGGTCACCCGTCTGCCCAGCGGCTATGGGCTGGCCTACCGCCTGACCCCTGGGGTGCACGAGCTGCCGGTGCAGCAGCCGGAGCACCGCATCCTGAAGGTGTCCATGAAAGAGCTCAACAAGAAAACCCCTCTCCTCACCGAGGGCCAGGCCATCTGCTTCACCATCCTGGGCGTGCTCACCAGCCTGGTGGTGCTGGGCACTGTGGGTATCGTCTTCCTCAACAAGTGCGAGACCTGGGTGTCCAACCTGCGCTACAACCACATGCTGCGGAAGAAGAAGAACCTGCTGCTTCAGTACAACAGCGGGGAGGACCTGGCCGTCAACATCATCTTCCCCGAGAAGATCGACATGACCACCTTCAGCAAGGAGGCCGGCGACGAGGAGATCTAA |
| sequence of protein | MTATEALLRVLLLLLAFGHSTYGAECFPACNPQNGFCEDDNVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDGWDGELCDRDVRACSSAPCANNGTCVSLDDGLYECSCAPGYSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCLCPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRCPAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLCKPEFTGLTCVKKRALSPQQVTRLPSGYGLAYRLTPGVHELPVQQPEHRILKVSMKELNKKTPLLTEGQAICFTILGVLTSLVVLGTVGIVFLNKCETWVSNLRYNHMLRKKKNLLLQYNSGEDLAVNIIFPEKIDMTTFSKEAGDEEI | |
| Database link | RefSeq | NM_003836 |
| UniProt | ||
| CCDS |
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Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
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| Disease | Summary |
| This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal. [provided by RefSeq, Nov 2015] |
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