Human cDNA
| Basic Informations | Advanced Informations |
| Clone information |
Clone ID | hMU012363 |
| Korean Unigene Clone | IRAU-72-G03 | |
| Original Clone | IRAL-34-A12 | |
| Vector | pOTB7 | |
| Gene | FASLG | |
| Gene Description | Fas ligand | |
| Clone sequence size | 1805 (bp) | |
| Fullness | F | |
| Mutation | - | |
| Amino acid - mutation | - | |
| Price | \77,000 (부가세 포함가) |
| Clone information |
5' end sequenced Length | 1805 |
| Sequence | CAGGGTCCCGTCCTTGACACCTCAGCCTCTACAGGACTGAGAAGA AGTAAAACCGTTTGCTGGGGCTGGCCTGACTCACCAGCTGCCATG CAGCAGCCCTTCAATTACCCATATCCCCAGATCTACTGGGTGGAC AGCAGTGCCAGCTCTCCCTGGGCCCCTCCAGGCACAGTTCTTCCC TGTCCAACCTCTGTGCCCAGAAGGCCTGGTCAAAGGAGGCCACCA CCACCACCGCCACCGCCACCACTACCACCTCCGCCGCCGCCGCCA CCACTGCCTCCACTACCGCTGCCACCCCTGAAGAAGAGAGGGAAC CACAGCACAGGCCTGTGTCTCCTTGTGATGTTTTTCATGGTTCTG GTTGCCTTGGTAGGATTGGGCCTGGGGATGTTTCAGCTCTTCCAC CTACAGAAGGAGCTGGCAGAACTCCGAGAGTCTACCAGCCAGATG CACACAGCATCATCTTTGGAGAAGCAAATAGGCCACCCCAGTCCA CCCCCTGAAAAAAAGGAGCTGAGGAAAGTGGCCCATTTAACAGGC AAGTCCAACTCAAGGTCCATGCCTCTGGAATGGGAAGACACCTAT GGAATTGTCCTGCTTTCTGGAGTGAAGTATAAGAAGGGTGGCCTT GTGATCAATGAAACTGGGCTGTACTTTGTATATTCCAAAGTATAC TTCCGGGGTCAATCTTGCAACAACCTGCCCCTGAGCCACAAGGTC TACATGAGGAACTCTAAGTATCCCCAGGATCTGGTGATGATGGAG GGGAAGATGATGAGCTACTGCACTACTGGGCAGATGTGGGCCCGC AGCAGCTACCTGGGGGCAGTGTTCAATCTTACCAGTGCTGATCAT TTATATGTCAACGTATCTGAGCTCTCTCTGGTCAATTTTGAGGAA TCTCAGACGTTTTTCGGCTTATATAAGCTCTAAGAGAAGCACTTT GGGATTCTTTCCATTATGATTCTTTGTTACAGGCACCGAGAATGT TGTATTCAGTGAGGGTCTTCTTACATGCATTTGAGGTCAAGTAAG AAGACATGAACCAAGTGGACCTTGAGACCACAGGGTTCAAAATGT CTGTAGCTCCTCAACTCACCTAATGTTTATGAGCCAGACAAATGG AGGAATATGACGGAAGAACATAGAACTCTGGGCTGCCATGTGAAG AGGGAGAAGCATGAAAAAGCAGCTACCAGGTGTTCTACACTCATC TTAGTGCCTGAGAGTATTTAGGCAGATTGAAAAGGACACCTTTTA ACTCACCTCTCAAGGTGGGCCTTGCTACCTCAAGGGGGACTGTCT TTCAGATACATGGTTGTGACCTGAGGATTTAAGGGATGGAAAAGG AAGACTAGAGGCTTGCATAATAAGCTAAAGAGGCTGAAAGAGGCC AATGCCCCACTGGCAGCATCTTCACTTCTAAATGCATATCCTGAG CCATCGGTGAAACTAACAGATAAGCAAGAGAGATGTTTTGGGGAC TCATTTCATTCCTAACACAGCATGTGTATTTCCAGTGCAATTGTA GGGGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATGACTAAAG AGAGAATGTAGATATTGTGAAGTACATATTAGGAAAATATGGGTT GCATTTGGTCAAGATTTTGAATGCTTCCTGACAATCAACTCTAAT AGTGCTTAAAAATCATTGATTGTCAGCTACTAATGATGTTTTCCT ATAATATAATAAATATTTATGTAGATGTGCATTTTTGTGAAATGA AAACATGTAATAAAAAGTATATGTTAGGATACAAAAAAAAAAAAA AAAAA |
| vector name | |
| vector source | |
| enzyme site(DNA insert) | |
| sequencing primer | |
| vector sequence | |
| Gene Location | Chromosome | 1 | |||||||||||
| Location | 1q23 | ||||||||||||
| Strand |
|
||||||||||||
| Database links | RefSeq | NM_000639 | |||||||||||
| KEGG Genes | 356 | ||||||||||||
| GeneCard | FASLG |
| sequence | sequence of CDS | ATGCAGCAGCCCTTCAATTACCCATATCCCCAGATCTACTGGGTGGACAGCAGTGCCAGCTCTCCCTGGGCCCCTCCAGGCACAGTTCTTCCCTGTCCAACCTCTGTGCCCAGAAGGCCTGGTCAAAGGAGGCCACCACCACCACCGCCACCGCCACCACTACCACCTCCGCCGCCGCCGCCACCACTGCCTCCACTACCGCTGCCACCCCTGAAGAAGAGAGGGAACCACAGCACAGGCCTGTGTCTCCTTGTGATGTTTTTCATGGTTCTGGTTGCCTTGGTAGGATTGGGCCTGGGGATGTTTCAGCTCTTCCACCTACAGAAGGAGCTGGCAGAACTCCGAGAGTCTACCAGCCAGATGCACACAGCATCATCTTTGGAGAAGCAAATAGGCCACCCCAGTCCACCCCCTGAAAAAAAGGAGCTGAGGAAAGTGGCCCATTTAACAGGCAAGTCCAACTCAAGGTCCATGCCTCTGGAATGGGAAGACACCTATGGAATTGTCCTGCTTTCTGGAGTGAAGTATAAGAAGGGTGGCCTTGTGATCAATGAAACTGGGCTGTACTTTGTATATTCCAAAGTATACTTCCGGGGTCAATCTTGCAACAACCTGCCCCTGAGCCACAAGGTCTACATGAGGAACTCTAAGTATCCCCAGGATCTGGTGATGATGGAGGGGAAGATGATGAGCTACTGCACTACTGGGCAGATGTGGGCCCGCAGCAGCTACCTGGGGGCAGTGTTCAATCTTACCAGTGCTGATCATTTATATGTCAACGTATCTGAGCTCTCTCTGGTCAATTTTGAGGAATCTCAGACGTTTTTCGGCTTATATAAGCTCTAA |
| sequence of protein | MQQPFNYPYPQIYWVDSSASSPWAPPGTVLPCPTSVPRRPGQRRPPPPPPPPPLPPPPPPPPLPPLPLPPLKKRGNHSTGLCLLVMFFMVLVALVGLGLGMFQLFHLQKELAELRESTSQMHTASSLEKQIGHPSPPPEKKELRKVAHLTGKSNSRSMPLEWEDTYGIVLLSGVKYKKGGLVINETGLYFVYSKVYFRGQSCNNLPLSHKVYMRNSKYPQDLVMMEGKMMSYCTTGQMWARSSYLGAVFNLTSADHLYVNVSELSLVNFEESQTFFGLYKL | |
| Database link | RefSeq | NM_000639 |
| UniProt | ||
| CCDS |
|
||||||||||||||||||||||||||||||||||||||||||
|
Gene Ontology Provided by GOA (www.ebi.ac.uk/GOA)
|
| Disease | Summary |
| This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014] |
|
|||||||||||
